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Full tests of Somastim - New GH by Western-Biotech

sciroxx-lab

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I'll try to explain in clear English the scientific description and terms in the attached document, sorry in advance - my English is not perfect

The first 4 paragraphs are a brief of the manufacturing process

The 5th paragraph discusses the quality assurance testing, and is the most interesting and relevant part to us -

When extracting proteins such as GH they have a tendency to create isomers - what I refer to is that 2 GH molecules or more are folded together, this form of the GH is biologically not active.

The first graph shows a the desired size which confirms the appearance of the product as a monomer (one GH colecule seperated andd biologically active).

The second set of graphs is a HPLC prints of the set of analysis along the manufacturing process. As you may learn from the peak (or actually peaks) the GH when extracted from the bacteria contains several impurities (step1), mostly other proteins, and along the advanced purification process (step2+3) a purity GH of 98%+ is achieved (step4)

Another test which is mentioned is called LAL test, as described by USP/otherPharmacoepial and check the present of toxins and pyrogen to confirm the product is safe for injection, I didn't include it, and is done by another independent lab, there is simply no use to have such equipment in our facility, we just check per batch and pay like 80usd per test.

Now we go to the biological assay tests - these tests are unique to such peptides as GH and also called in vivo tests -
GH is a very delicate molecule. Slight harm in its 3 dimensional structure may harm its biological effect. For instance the the minor change in the slightest angle of the binding are to the receptor may prevent activation of the receptor. A very precise, careful purification process we developed to sustain the GH in its active form, which we confirm by the biological assay test. In our facility we use more advanced biological assay tests - we check the prolifiration of human cells under exposure to the GH in the product. this is currently the ultimate test, as it test directly the interaction of the GH with target receptor and quantifies its direct clinical effect.
When mice are injected with GH there are more factors are involved in their growth, like nutrition, genetic parameters, enviorment influence etc', of course the test tries to isolate the effect of GH by giving similar nutrition etc' to the mice, but as you understand it can't eliminate 100% such conditions.
In the biological assay.

In this Specific test the Somastim was fond to be about 6% more active then Saizen, but he clearly says that the statistical difference is not significant - and as u may see the graphs are quite identical.

This brings us to the serum tests which many relies on as an indication. (GH an IGF1 serum tests)

- Serum GH tests confirm the present and quantity of GH in the product. It's certainly not an indication to its clinical effect. It's a good start as it confirms that what the label declares is there, but it's certainly not the whole picture - it confirms the present of GH in the blood, but it certainly doesn't check biological activity of the GH - it doesn't check the form of the GH (monomers which is the active biological form) and not it's intact 3 dimensional structure)


- IGF1 serum tests clearly gives a valid indication to the clinical effect of the GH, but the results may widely vary as the IGF secretion (mainly in liver, as well as kidneys) depends also on many other factors such as nutrition, other hormonees like sex hormones, stress hormones insulin and glucagon, so the numbers this test brings are not an ultimate measure.

This is the significant of the biological assay in vivo tests
 

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Exactly.. We like all this effort but what's really going to help you is showing some labs of serums and igf done by either a mod or someone of similar stature.. Then wel pay attention to the rest
 
Exactly.. We like all this effort but what's really going to help you is showing some labs of serums and igf done by either a mod or someone of similar stature.. Then wel pay attention to the rest

All the tests in the world will not convince the "HGH connoisseurs" that the product is as good as advertised. As of yet, I have not heard of anyone having the new product in hand, never mind actually performing their own HGH Serum and IGF-1 test. Now before people ask "Aren't you the same guy on another thread proclaiming him the best in the world?" Yes, that be me. But understand, I am also one of the Sciroxx customers who received the Blue Tops that tested in the single digits. I would love to see a Pharm Grade quality generic as compensation.
 
All the tests in the world will not convince the "HGH connoisseurs" that the product is as good as advertised. As of yet, I have not heard of anyone having the new product in hand, never mind actually performing their own HGH Serum and IGF-1 test. Now before people ask "Aren't you the same guy on another thread proclaiming him the best in the world?" Yes, that be me. But understand, I am also one of the Sciroxx customers who received the Blue Tops that tested in the single digits. I would love to see a Pharm Grade quality generic as compensation.[

There's never too much good gh floating around and when the top players have to compete we all win.. So I too hope this plays out well
 
I'm still waiting I'm sure it should be here any day. I'll test asap. I just can't imagine he would even send it if he wasn't confident. It would ruin him in my opinion
 
Better quality copies of the lab tests for your request
 

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I have a feeling this is going to be a huge thread!! Great news on test results!!!
 
What's up with the red lumps at injection site I keep reading about? That is never supposed to happen!
 
So far I've seen a couple of such reports, and we do investigate it, we speculate it stems from deterioration of one of the excipients under heat.
The investigation may take a bit, we test it now on small rabbit which are used in the pharmaceutical industry for this purpose prior human trials.

I assure all the parameters of the GH regarding quality, purity and potency, just like the serum tests so far showed consistently (check the thread on the Somastim) a mess specs tests that members here arrange will prove as well.
 
This is the lab test forum.
It's for results
And facts.

Feedback goes In
The sponsor
Section.
 
Expect new IGf1 tests to be post soon following 4 weeks protocol
 

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