OXYTOCIN...reduced social anxiety

johnjuanb1 · Apr 7, 2014

Given its ability to break-down social barriers, induce feelings of optimism, increase self-esteem, and build trust, oxytocin is increasingly being seen as something that can help people overcome their social inhibitions and fears. Studies are showing that it may be effective in treating debilitating shyness, or to help people with social anxieties and mood disorders.

Chronic enhancement of brain oxytocin levels causes enduring anti-aggressive and pro-social explorative behavioral effects in male rats.

AuthorsCalcagnoli F, et al. Show all Journal
Horm Behav. 2014 Mar 26. pii: S0018-506X(14)00049-X. doi: 10.1016/j.yhbeh.2014.03.008. [Epub ahead of print]

ABSTRACT

Oxytocin (OXT) has been implicated in the regulation of social behaviors, including intermale offensive aggression. Recently, we showed that acute enhancement of brain OXT levels markedly suppressed offensive aggression and increased social exploration in resident rats confronted with an intruder in their home territory. Moreover, a different responsivity to the exogenous OXTergic manipulation was observed among individuals based on their baseline aggression. In this study we aimed at evaluating the behavioral response to chronically enhancing or attenuating central OXT levels, and at scrutinizing whether the trait-aggression moderates the treatment-induced behavioral changes. To this end, resident male wild-type Groningen rats were continuously (via osmotic minipumps) intracerebroventricularly infused with synthetic OXT or a selective OXT receptor (OXTR) antagonist for 7days. Changes in behavior were assessed performing a resident-intruder test before and at the end of the treatment period, as well as after 7days of withdrawal. Chronic infusion of OXT was found to selectively suppress aggression and enhance social exploration. Chronic blockage of OXTRs instead increased introductory aggressive behavior (i.e. lateral threat), yet without affecting the total duration of the aggression. The magnitude of the anti-aggressive changes correlated positively with the level of baseline aggression. Interestingly, OXT-induced behavioral changes persisted 7days after cessation of the treatment. In conclusion, these findings provide further evidence that enhanced functional activity of the central OXTergic system decreases social offensive aggression while it increases social explorative behavior. The data also indicate that chronically enhancing brain OXT levels may cause enduring anti-aggressive and pro-social explorative behavioral effects.

johnjuanb1 · Apr 7, 2014

PAIN and WOUND HEALING

PAIN and WOUND HEALING

Oxytocin can also be used to heal wounds (through its anti-inflammatory properties). Studies have also shown that a rise in oxytocin levels can relieve pain — everything from headaches, cramps and overall body aches.

johnjuanb1 · Apr 7, 2014

OXYTOCIN CHARACTERISTICS:

- Reduced muscle tension
- Temporarily reduced appetite but increasing appetite with long term use
- Stimulates digestion on full stomach
- Increased urination (diuretic effect)
- Faster healing wounds and reduced inflammation
- Increase in growth hormone
- Stimulates mating
- More social contact between individuals
- Increased boldness and curiosity
- Sleep inducing effect (with high dosages)
- Diminished pain sensation
- Improved learning

Saizen · Apr 7, 2014

What's the dosage?

Capin · Apr 7, 2014

Tequilla also has the ability to break-down social barriers, induce feelings of optimism, increase self-esteem, and build trust, tequilla is increasingly being seen as something that can help people overcome their social inhibitions and fears. Studies are showing that it may be effective in treating debilitating shyness, or to help people with social anxieties and mood disorders.
I prefer Patron Anejo

Capin · Apr 7, 2014

Srry JJ no disrespect intended just had to throw that out there lol

johnjuanb1 · Apr 7, 2014

Capin said:
Srry JJ no disrespect intended just had to throw that out there lol

Tequila has gotten many a man some good poonannie

johnjuanb1 · Apr 7, 2014

Saizen said:
What's the dosage?

Here is a post from another forum. Apparently, oxytocin comes in 10unit tabs, meaning 10mcg. That's 200 doses in a 2mg peptide vial.

"Belmar Pharmacy www.belmarpharmacy.com is a compounding pharmacy in Colorado that offers oxytocin tablets that can actually be absorbed through the gastrointestinal tract. They are able to do this through a patented absorption system. These tablets are pure oxytocin. After a single 10 unit dosage, I felt a sense of calm and relaxation for nearly six hours. These tablets require a physician’s prescription. If you can get your doctor to write a script (print off some of the articles and resources on wwww.oxytocincentral.com for their information), you can order them from Belmar and they’ll ship them directly to you. They can’t ship outside the country so if you live in Canada or New Zealand, you must have them shipped to a friend in the US and then have the friend ship them to you. These tablets are very effective. Taken appropriately, they offer a multitude of benefits. I currently have about 15 clients taking them on an experimental basis. So far, the results are very positive. This is not an inexpensive drug. A one month supply of the 10 IU tablets will cost approximately $70 per month and is not covered by insurance."

Capin · Apr 7, 2014

Seriously this sounds interesting I git a bit edgy, crabby, short tempered when on heavy would this help with that JJ

johnjuanb1 · Apr 7, 2014

Capin said:
Seriously this sounds interesting I git a bit edgy, crabby, short tempered when on heavy would this help with that JJ

Yes, it reduces aggressive behavior and increases empathy.

johnjuanb1 · Apr 7, 2014

OXYTOCIN INTENSIFIES ORGASMS

'Love Hormone' Oxytocin May Intensify Orgasms
04/04/14 11:10 AM ET
By Rachael Rettner, Senior Writer Published: 04/04/2014 05:00pm EST on LiveScience

A dose of the "love hormone" oxytocin may make people's orgasms more intense, a new study from Germany suggests.

In the study, 29 healthy couples who'd been together for at least a year took either an oxytocinnasal spray or a placebo spray before having sex in their home. After intercourse, participants completed a survey about their sexual experience as well as their feelings toward their partner.

Oxytocin had no effect on sex drive or arousal for either men or women, nor did it affect the ability to achieve an erection for men, or vaginal lubrication for women. [11 Interesting Effects of Oxytocin]

But those who took oxytocin before sex — especially men — reported slightly more intense orgasms, as well as greater levels of contentment after sex. In addition, men who took oxytocin said they felt more sexually sated after sex than those who took the placebo.

Some women who took oxytocin reported that they were better able to share their sexual desires and empathize with their partners during sex.

"This field study demonstrates that [oxytocin] may alter specific aspects of sexual experience and partner interactions in healthy couples," the researchers, from Hannover Medical School in Germany, wrote in the March issue of the journal Hormones and Behavior.

Previous studies have suggested that oxytocin plays a role in relationship bonding, and the hormone is known to be released from the brain's pituitary gland during orgasm. But few studies have examined whether higher levels of the hormone affect sexual behavior.

The researchers noted that even though oxytocin seemed to intensify people's orgasms, the effect was rather modest. For example, men who took the hormone rated their contentment after sex about half a point higher (on a six-point scale) than those who took the placebo. This may be because oxytocin is already released during sex, so the effect of additional oxytocin may not be very large, the researchers said.

The researchers also noted the study was small and involved adults who reported no sexual problems. Future studies are needed to confirm the findings and to see whether the hormone may help those with sexual dysfunction, such those as low sexual desire or erectile dysfunction, the researchers said.

bigbumpkin2003 · Apr 7, 2014

I have social anxiety and panic attacks....Benzodiazepine makes my life much more tolerable since my diagnosis

Akamai · Apr 8, 2014

Maybe be reason for pause???

Oxytocin Could Make You Racist, New Study Finds - TIME

Ak

NGL34 · Apr 8, 2014

truth

jack off before a hot date or a before social event--> oxytocin released --> no more anxiety (well at least until the refractory phase is over)

johnjuanb1 · Apr 8, 2014

Akamai said:
Maybe be reason for pause???

Oxytocin Could Make You Racist, New Study Finds - TIME

Ak

Hahaha wtf????

johnjuanb1 · Apr 8, 2014

NGL34 said:
jack off before a hot date or a before social event--> oxytocin released --> no more anxiety (well at least until the refractory phase is over)

Old fuggers can't risk jacking off before a date. It may not get hard again. Guess that's when you take dapoxetine and Avanafil.

johnjuanb1 · Apr 8, 2014

SPONTANEOUS ERECTIONS

Oxytocin--anatomy and functional assignments: a minireview.

AuthorsKiss A, et al. Show all Journal
Endocr Regul. 2005 Sep;39(3):97-105.

ABSTRACT

Oxytocin (OXY) is a very abundant neuropeptide exerting a wide spectrum of central and peripheral effects as neurohormone, neurotransmitter, or neuromodulator. In the central nervous system (CNS), the OXY gene is predominantly expressed in magnocellular neurons in the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei. The magnocellular OXY neurons release their products into the general circulation in the neurohypophysis while the mediocellular OXY neurons secrete elsewhere in the CNS. OXY is also produced in peripheral tissues, e.g., uterus, placenta, amnion, corpus luteum, testis, and heart. OXY is a potent stimulator of spontaneous erections in rats and is involved in ejaculation. The typical actions of peripheral OXY are stimulation of uterine smooth muscle contraction during labor and milk ejection during lactation. OXY acts via the receptor which is a typical class of I G protein-coupled receptor. OXY receptors have also been identified in other tissues, including the kidney, heart, thymus, pancreas, and adipocytes.