.gif "IP Gear")
- Joined
- Oct 18, 2012
- Messages
- 241
Hi guys. I am researching to do a write up on ipamorelin and need some help working out molecular weight conversions. In a clinical trial conducted on 48 adult males, doses ranged from 4.2nmol/kg up to 140.45nmol/kg which were deemed to be safe. Now that is a far cry from the normal 100mcg up to maximum 500mcg dosing that we usually use. I need help confirming that my calculation is right.
Ipamorelin's molecular weight is 711.853g/mol.
Therefore 1µmol=711.853mcg and 1nmol = 0.711853mcg, correct?
That would mean at 140.45nmol/kg as in the study a 100kg/220lb male would be given a massive dose of up to 10mg (9997.98mcg)
of ipamorelin!
Are my calculations correct? 0.711853mcg x 140.45 x 100kg = 9997.98mcg
What is very interesting is that the study found that a mega dose of ipamorelin can result in a massive release of Growth Hormone up to the entire amount present in the pituitary, whereas other GHRPs like GHRP2/GHRP6 become less effective the higher you go over the 1mcg/KG saturation dose.
Ipamorelin's molecular weight is 711.853g/mol.
Therefore 1µmol=711.853mcg and 1nmol = 0.711853mcg, correct?
That would mean at 140.45nmol/kg as in the study a 100kg/220lb male would be given a massive dose of up to 10mg (9997.98mcg)
of ipamorelin!Are my calculations correct? 0.711853mcg x 140.45 x 100kg = 9997.98mcg
What is very interesting is that the study found that a mega dose of ipamorelin can result in a massive release of Growth Hormone up to the entire amount present in the pituitary, whereas other GHRPs like GHRP2/GHRP6 become less effective the higher you go over the 1mcg/KG saturation dose.
