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New treatments being used for hairloss.
Platelet Rich Plasma therapy (PRP)
Platelet Rich Plasma or PRP is a revolutionary new treatment for hair loss. It is versatile and can be used with hair transplant surgery, or as an independent treatment for thinning hair. Many hair transplant surgeons are already using this technology in their hair replacement surgery, and since the expert presentations to over 400 surgeons at the ISHRS conference in July, many more will soon start using the procedure.
PRP therapy is performed in 3 stages. First, an amount of blood between 60-100ml is taken from the patient and centrifuged. The fraction that contains the most platelets and growth factors is then removed and kept. The platelet rich fraction may be divided and one part lysed to release more growth factors then combined with the other whole-platelet factor. This extra treatment is claimed to increase the effects of PRP therapy, especially for hair loss.
Secondly the scalp is stimulated to activate the wound healing process. This process needs to be activated in order to use the growth factors and platelets that PRP therapy gives. Previously PRP activation needed to be completed with a single needle. 100's of punctures are necessary for the activation step, and so using a single needle was impractical and caused the patient significant amounts of pain. Now, a new product called the Scalproller manufactured by Nanogen is widely used for the activation step. The Scalproller is a microneedle roller that uses 192 unique titanium needles to open the skin to the same depth every time, and as it uses less pressure it causes less pain. As the Scalproller is rolled over the scalp, it saves the surgeon time as well.
The third step in the PRP process is the re-injection of the platelet and growth factor rich fragment into the scalp. This provides high levels of every factor needed for healing and healthy hair growth, the factors are utilised by the stimulated cells, including hair follicles.
The stimulation and access to high concentrations of growth factors has been shown to generate new hair growth, thicken existing hair growth, and make hair transplants grow thicker and healthier. In one case an Alopecia Areata patient was treated, and PRP treatment caused hair regrowth.
These findings were presented at the ISHRS conference along with the launch of Nanogen's Scalproller, and PRP with Scalproller pre-treatment is looking to become widespread as a hair loss treatment.
Written by Toby Cobbledick for Nanogen Hair Loss Research
Extracellular Matrix (“ECM”) ACell Inc.,
Hair Loss Solutions And News / Extracellular Matrix Used on Injured Soldiers : What This Could Mean for Hair Loss Sufferers
Extracellular Matrix Used on Injured Soldiers : What This Could Mean for Hair Loss Sufferers
Posted by Emilie on Tuesday, May 4, 2010
The Daily Mail, a popular British periodical, recently did a feature on the use of extracellular matrix (ECM) products on soldiers injured in Afghanistan. ECM is derived from the porcine membrane of bladder and can be used as a regenerative medicine. The Daily Mail article claims that it has even been used to save soldiers who were so badly injured at war that they risked amputation. In one example, the ECM product was used to repair a massive leg wound; it was able to grow nerves, muscles and ordinary tissue where there had been none. ACell, Inc., a company based in Columbia, Maryland, has developed and refined what they consider, “the next generation of regenerative medicine.”
ACell is just one variety of ECM recently FDA-approved for use in humans. When applied to injured tissue, ACell can stimulate the regeneration of normal tissue. Several pioneering hair transplant surgeons took an early interest in ACell and have been studying possible uses for the product as it relates to hair restoration. Doctors Jerry Cooley and Gary Hitzig released some of the first reports about their findings on whether ACell might be beneficial for strip surgery patients. Unfortunately, at this time, their reports are inconclusive.
Dr. Cole has been following news of ACell since 2007. Now that it is indicated for safe use in humans, he is researching ACell as it relates to his Cole Isolation Technique (CIT) patients. He is currently exploring whether the use of ACell may reduce the appearance of hypopigmentation, the tiny white spotting that some FUE and CIT patients develop when grafts are removed from the donor region. Dr. Cole is hopeful that ACell may help to improve melanocyte stimulation, and to improve the overall appearance of the donor area.
A secondary interest Dr. Cole has in ACell is whether it will stimulate cells left behind when grafts are extracted, and possibly induce the development of new hair growth. The hope is that, through the delivery of ACell to our extraction sites, he will be able to attract and induce hair follicle stem cells to reproduce a re-growth of the extracted follicles. At this time, Dr. Cole has not yet seen any evidence that ACell promotes any new hair growth. The objective going forward is to unlock the specific methods necessary to regenerate hair. Given that ACell has already successfully regenerated muscle, skin, nerves, specific organ tissue, etc., it is reasonable to suspect that it should be able to regenerate hair. The challenge lies in engineering a specific means of delivering the product to the appropriate stem cells.
To read the complete Daily Mail article, click here:
"Magic ‘Pixie Dust’ made from pig bladders helps ‘regrow’ limbs of wounded soldiers"
http://www.dailymail.co.uk/sciencet...-bladders-regrows-limbs-wounded-soldiers.html
"MatriStem MicroMatrix – Regenerative Medicine and Hair Cloning"
**broken link removed**
Another company using ECM Histogen "HSC Trial Shows Continued Significant Hair Growth at One Year Follow-up" halfway down page of the Link
**broken link removed**
Platelet Rich Plasma therapy (PRP)
Platelet Rich Plasma or PRP is a revolutionary new treatment for hair loss. It is versatile and can be used with hair transplant surgery, or as an independent treatment for thinning hair. Many hair transplant surgeons are already using this technology in their hair replacement surgery, and since the expert presentations to over 400 surgeons at the ISHRS conference in July, many more will soon start using the procedure.
PRP therapy is performed in 3 stages. First, an amount of blood between 60-100ml is taken from the patient and centrifuged. The fraction that contains the most platelets and growth factors is then removed and kept. The platelet rich fraction may be divided and one part lysed to release more growth factors then combined with the other whole-platelet factor. This extra treatment is claimed to increase the effects of PRP therapy, especially for hair loss.
Secondly the scalp is stimulated to activate the wound healing process. This process needs to be activated in order to use the growth factors and platelets that PRP therapy gives. Previously PRP activation needed to be completed with a single needle. 100's of punctures are necessary for the activation step, and so using a single needle was impractical and caused the patient significant amounts of pain. Now, a new product called the Scalproller manufactured by Nanogen is widely used for the activation step. The Scalproller is a microneedle roller that uses 192 unique titanium needles to open the skin to the same depth every time, and as it uses less pressure it causes less pain. As the Scalproller is rolled over the scalp, it saves the surgeon time as well.
The third step in the PRP process is the re-injection of the platelet and growth factor rich fragment into the scalp. This provides high levels of every factor needed for healing and healthy hair growth, the factors are utilised by the stimulated cells, including hair follicles.
The stimulation and access to high concentrations of growth factors has been shown to generate new hair growth, thicken existing hair growth, and make hair transplants grow thicker and healthier. In one case an Alopecia Areata patient was treated, and PRP treatment caused hair regrowth.
These findings were presented at the ISHRS conference along with the launch of Nanogen's Scalproller, and PRP with Scalproller pre-treatment is looking to become widespread as a hair loss treatment.
Written by Toby Cobbledick for Nanogen Hair Loss Research
Extracellular Matrix (“ECM”) ACell Inc.,
Hair Loss Solutions And News / Extracellular Matrix Used on Injured Soldiers : What This Could Mean for Hair Loss Sufferers
Extracellular Matrix Used on Injured Soldiers : What This Could Mean for Hair Loss Sufferers
Posted by Emilie on Tuesday, May 4, 2010
The Daily Mail, a popular British periodical, recently did a feature on the use of extracellular matrix (ECM) products on soldiers injured in Afghanistan. ECM is derived from the porcine membrane of bladder and can be used as a regenerative medicine. The Daily Mail article claims that it has even been used to save soldiers who were so badly injured at war that they risked amputation. In one example, the ECM product was used to repair a massive leg wound; it was able to grow nerves, muscles and ordinary tissue where there had been none. ACell, Inc., a company based in Columbia, Maryland, has developed and refined what they consider, “the next generation of regenerative medicine.”
ACell is just one variety of ECM recently FDA-approved for use in humans. When applied to injured tissue, ACell can stimulate the regeneration of normal tissue. Several pioneering hair transplant surgeons took an early interest in ACell and have been studying possible uses for the product as it relates to hair restoration. Doctors Jerry Cooley and Gary Hitzig released some of the first reports about their findings on whether ACell might be beneficial for strip surgery patients. Unfortunately, at this time, their reports are inconclusive.
Dr. Cole has been following news of ACell since 2007. Now that it is indicated for safe use in humans, he is researching ACell as it relates to his Cole Isolation Technique (CIT) patients. He is currently exploring whether the use of ACell may reduce the appearance of hypopigmentation, the tiny white spotting that some FUE and CIT patients develop when grafts are removed from the donor region. Dr. Cole is hopeful that ACell may help to improve melanocyte stimulation, and to improve the overall appearance of the donor area.
A secondary interest Dr. Cole has in ACell is whether it will stimulate cells left behind when grafts are extracted, and possibly induce the development of new hair growth. The hope is that, through the delivery of ACell to our extraction sites, he will be able to attract and induce hair follicle stem cells to reproduce a re-growth of the extracted follicles. At this time, Dr. Cole has not yet seen any evidence that ACell promotes any new hair growth. The objective going forward is to unlock the specific methods necessary to regenerate hair. Given that ACell has already successfully regenerated muscle, skin, nerves, specific organ tissue, etc., it is reasonable to suspect that it should be able to regenerate hair. The challenge lies in engineering a specific means of delivering the product to the appropriate stem cells.
To read the complete Daily Mail article, click here:
"Magic ‘Pixie Dust’ made from pig bladders helps ‘regrow’ limbs of wounded soldiers"
http://www.dailymail.co.uk/sciencet...-bladders-regrows-limbs-wounded-soldiers.html
"MatriStem MicroMatrix – Regenerative Medicine and Hair Cloning"
**broken link removed**
Another company using ECM Histogen "HSC Trial Shows Continued Significant Hair Growth at One Year Follow-up" halfway down page of the Link
**broken link removed**
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