We alway see people asking which “fat burner” to use , which works better , which ones stack best with other ones.
So I was thinking about what mechanisms that these different ones use. Like we know that HGH helps release fat to be burned , yohimbine helps to release and oxide fat , L-Carnitine help mobilize fat to be burned as energy , DNP well I’m not really sure exactly how it works , T3 raises metabolism.
Is anyone exactly sure how these compounds work??
What would be the best sup to stack with what??
Yohimbine: Alpha adrenergic 2 receptor antagonist. It blocks this receptor which is found in higher quantities in stubborn fat like low abs, etc.
T3: Increases lipolysis but also protein breakdown and glycogen turn over. Fairly poor compound on it's own but can potentiate the effects of other fat burners by sensitizing adrenergic receptors to stimulants. In higher doses +50 mcg can make you flat, decrease endurance and strength.
HGH: Increases the body's use of fat for energy instead of glucose. It has been shown in studies to increase resting metabolic rate.
Ephedrine or EC stack: Beta adrenergic receptor agonist. Activates beta receptors which increases lipolysis and is a powerful stimulant as well as appetite suppressant, everything you need on a cut. Works great as a pre-workout and makes it easier to eat less.
Clenbuterol: Similar to Ephedrine with the same mechanism of action. It can help you breath easier which is useful if you get shortness of breath from trenbolone. Some people get bad shakes from it, but it's effective. Numbers are thrown around that it can increase your TDEE by 10% but haven't seen any hard data to support that.
DNP: Makes the mitochondria less efficient at producing energy, thereby producing excess energy as heat. At 250 mg, fairly safe compound with mild sides but can kill you at higher doses due to there being no limit on how much heat it will make you produce in excess dosages. Sides are much more apparent past 250 mg and can include fatigue and increased hunger.
My 2 cents:
Caloric deficit is king and 90% of your results will come from your deficit. 20-30% depending on how aggressive you want to be is ideal. Some people push to 40% deficit, but risk of muscle and strength loss is much higher.
Yohimbine is ideal when you are at 12% and under since it works best on stubborn fat.
Ephedrine is a good overall fat burner since it increases TDEE(calories burned daily), decreases appetite making deficit easier, and powerful stimulant to keep your workouts intense even though you are on a deficit and depleted.
DNP is the most potent and potentially dangerous (if used irresponsibly).
T3 is great for lagging energy levels on a cut and at 25-50 mcg can restore energy but it can also increase appetite.
You can stack caffeine with pretty much any one of the fat burners.