HCG everyday on-cycle and TRT - dosage

[Biggerp73]

Anyone take HCG everyday? Ive been doing 500 EOD but yesterday I was reading someone say they did 100 everyday to mimic the natural release.

 

[Swifto]

No, its not needed every day and there is a refractory period where the leydig cell response is impaired after HCG administration for 48-72 hours. So its best dosed twice per week IMO or at most, every other day (EOD).

 

[Kaladryn]

Swifto is correct, remember there is no "natural release" of HCG, LH and FSH are very short-lived pulsatile hormones but HCG stays around unnaturally long. You would have the opposite effect of what you are looking for, I have tried 3x per week many times and it was clearly building up. Little known fact you can google: HCG is immunosuppressive also, I've gotten sick many times (cold/flu) after doing too much of it (we used dumb amounts in the 90s...).

The biologic half-life of LH is 20 minutes, shorter than that of FSH (3–4 hours) and hCG (24 hours).