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Stem Cell - Exosome -Regenerative Therapy

Viking55

Active member
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Jan 16, 2010
Messages
806
Aloha PM,

Long and short of it is that, I significantly injured my surgical repaired lumbar spine while surfing in the islands in July. Not a lot of feeling in my feet, legs, with paresthesia. Walking and moving was very difficult and painful. Had back surgery for lumbar spinal stenosis in 2015.

I've been investigating stem cell and exosome therapies, and viewing hundreds of studies and the results are consistently impressive!! Add in some state of the art regenerative and functional medicine protocols, and the results are even more impressive!!

Also, during my lifetime I have incurred so many injuries and trauma to my body, organs, brain, from alcohol, drugs, multiple near death episodes, concussions, etc.

Anyway, I have a comprehensive consult this next week to start the process..I am all in!!

I will keep you all posted on this new journey, which I look forward to...

In health,
V
 
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Thanks. Stem cells are one thing that I think someday might be able to help heart patients like me. Let us know how it goes. It sounds like an expensive therapy. Does your health insurance pay anything toward it or is it all selfpay?
 
Yeah in debating on trying it for my arthritic shoulder..
 
Aloha Maldorf,

Yes, it's all self pay. However, they have a few options on regarding payment. They even have a financing company for a longer term payment plan. Cash discount too.

V
 
Wish you all the best Viking! Please let us know how everything goes, really interested in this.
 
Really interesting stuff. This is something I've kept a close eye on in recent years.

Where is the clinic located and what type of stem cells do they use (umbilical cord, bone marrow, your own fat, etc)?
 
Aloha,

From all the research and studies I have I have viewed, Umbilical cords consistently provide the most potent stem cells. The usual protocol is if you are under 50, bone marrow or adipose tissue.

The umbilical cords this group is using comes out of Utah, thoroughly tested, and from mothers less than 35 years of age, might be 30.

The clinic I will be doing this at is here in the bay area. The Functional Medicine doctor was spot on with his presentation. He also has other modalities he uses to enhance the treatments, light, and different frequencies of energy and sound patterning..

Also, he makes sure that you are dialed with nutrition, sleep, and having an optimal healthy lifestyle.

My treatment regime will consist of a site specific injection under a scope, plus an intravenous injection, and an intranasal application. Going for the full gusto...

At 65 now, I want to do what it takes to heal all the damage I have incurred, and seriously increase my qualities of life.

V
 
Aloha,



From all the research and studies I have I have viewed, Umbilical cords consistently provide the most potent stem cells. The usual protocol is if you are under 50, bone marrow or adipose tissue.



The umbilical cords this group is using comes out of Utah, thoroughly tested, and from mothers less than 35 years of age, might be 30.



The clinic I will be doing this at is here in the bay area. The Functional Medicine doctor was spot on with his presentation. He also has other modalities he uses to enhance the treatments, light, and different frequencies of energy and sound patterning..



Also, he makes sure that you are dialed with nutrition, sleep, and having an optimal healthy lifestyle.



My treatment regime will consist of a site specific injection under a scope, plus an intravenous injection, and an intranasal application. Going for the full gusto...



At 65 now, I want to do what it takes to heal all the damage I have incurred, and seriously increase my qualities of life.



V
Keep us updated please!!! I have heard a lot of good things about stem cells.

First hand experience would be awesome. Good luck Viking.

Sent from my S2 using Tapatalk
 
Im glad you are going to share your results. I hope you do it long term too.

I looked at trying this for a bit, I contacted a hospital and they approved me for treatment but I was concerned it wouldn't do a thing for my heart since the part that is dead is all scar tissue and from what I can find it seems that the only hope might be to directly inject stem cells into the scar tissue of the heart. Most of this is still just experimental.

I was going to take part in a stem cell study here but got turned down because my heart is too thin to inject into. If they inject into my heart it would punch all the way through my heart wall and I would most probably bleed out. I cant remember the cost they quoted me, but it was around $20k I think. Been awhile since I looked at it.
 
Im glad you are going to share your results. I hope you do it long term too.

I looked at trying this for a bit, I contacted a hospital and they approved me for treatment but I was concerned it wouldn't do a thing for my heart since the part that is dead is all scar tissue and from what I can find it seems that the only hope might be to directly inject stem cells into the scar tissue of the heart. Most of this is still just experimental.

I was going to take part in a stem cell study here but got turned down because my heart is too thin to inject into. If they inject into my heart it would punch all the way through my heart wall and I would most probably bleed out. I cant remember the cost they quoted me, but it was around $20k I think. Been awhile since I looked at it.

Stem cells go go every site of inflammation. Rearden mckenna institute is the best place to do it. Its 25k and in panama
 
Sorry to hear about the re-injury. Stem cells aren't going to fix stenosis caused by calcification (bone spurs).

What is the issue now with your back that you're thinking stem cells can help?
 
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Stem Cell Disc Regeneration Study

Aloha,

Yes, rabbits were used for the study..oh well I look like a rabbit anyway..lol

Format: Abstract Send to:
Am J Phys Med Rehabil. 2013 May;92(5):420-9. doi: 10.1097/PHM.0b013e31825f148a.
Human umbilical cord blood-derived mesenchymal stem cells in the cultured rabbit intervertebral disc: a novel cell source for disc repair.
Anderson DG1, Markova D, An HS, Chee A, Enomoto-Iwamoto M, Markov V, Saitta B, Shi P, Gupta C, Zhang Y.
Author information
1
Department of Orthopedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Abstract-

OBJECTIVE:
Back pain associated with symptomatic disc degeneration is a common clinical condition. Intervertebral disc (IVD) cell apoptosis and senescence increase with aging and degeneration. Repopulating the IVD with cells that could produce and maintain extracellular matrix would be an alternative therapy to surgery. The objective of this study was to determine the potential of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) as a novel cell source for disc repair. In this study, we intended to confirm the potential for hUCB-MSCs to differentiate and display a chondrocyte-like phenotype after culturing in micromass and after injection into the rabbit IVD explant culture. We also wanted to confirm hUCB-MSC survival after transplantation into the IVD explant culture.

DESIGN:
This study consisted of micromass cultures and in vitro rabbit IVD explant cultures to assess hUCB-MSC survival and differentiation to display chondrocyte-like phenotype. First, hUCB-MSCs were cultured in micromass and stained with Alcian blue dye. Second, to confirm cell survival, hUCB-MSCs were labeled with an infrared dye and a fluorescent dye before injection into whole rabbit IVD explants (host). IVD explants were then cultured for 4 wks. Cell survival was confirmed by two independent techniques: an imaging system detecting the infrared dye at the organ level and fluorescence microscopy detecting fluorescent dye at the cellular level. Cell viability was assessed by staining the explant with CellTracker green, a membrane-permeant tracer specific for live cells. Human type II collagen gene expression (from the graft) was assessed by polymerase chain reaction.

RESULTS:
We have shown that hUCB-MSCs cultured in micromass are stained blue with Alcian blue dye, which suggests that proteoglycan-rich extracellular matrix is produced. In the cultured rabbit IVD explants, hUCB-MSCs survived for at least 4 wks and expressed the human type II collagen gene, suggesting that the injected hUCB-MSCs are differentiating into a chondrocyte-like lineage.

CONCLUSIONS:
This study demonstrates the ability of hUBC-MSCs to survive and assume a chondrocyte-like phenotype when injected into the rabbit IVD. These data support the potential for hUBC-MSCs as a cell source for disc repair. Further measures of the host response to the injection and studies in animal models are needed before trials in humans.
 
Please keep this updated. I too have spinal stenosis with scoliosis. My spine is very unstable, I was scheduled for stenosis surgery with double fusion to stabilize the spine. All the horror stories on back surgery, I did not go through with it but do still have lots of issues. I am waiting for science to progress enough in this area. I have heard lots of great thing on stem cells for the spine. I hear they now are going directly into the spine with these injections and not near it.
Good luck
 
Aloha,

upeccmi-I've been dealing with progressing spinal instability since I had my surgery for spinal stenosis. It become worse when I got 'blown up' and bent backwards and sideways while surfing in the islands.

The doc who did the laminectomy 3-4-5, and laminotomy 5-S-1 in 2015, told me before the surgery that he may need to fuse me, and would know for sure after he opened me up..He didn't have to, thankfully!

Long and short of it, 3 weeks ago I went to see an ND and had prolotherapy, injections of a dextrose solution in and around 3-4-5-S-1, plus a certain combo of minerals, plus injections of ozone into the same area.

70% improvement. I can walk so much better. Not the same amount of morning and pm stiffness. Pain has decreased a lot.

Normally the treatment protocols call for 3-5 injections.

Check it out-Prolozone Therapy.

V
 
Viking I'm confused. You had surgery for stenosis and then re-injured your back. You didn't state what the re-injury is. The study refers to degenerative disc. You haven't mentioned that about yourself and DD is not an injury, it's something that happens to a lot of people over time. Like I said before, stem cell therapy can't repair stenosis. Viking what else is wrong with your back that you think stem cells might help? BTW, I have had back/spine issues for 33 years, so I feel your pain and I hope that you get the relief you're looking for!!

upeccmi stem cells won't help your stenosis. Stem cells don't dissolve bone (calcification). I read the horror stories online before my first fusion surgery. My spine specialist assured me that the people who have had successful surgery are out living their life, not posting. My fusion surgeries have been incredibly helpful! Don't be afraid to get them if you need to. They're not as debilitating as some make it out to be. If you're healthy and active, you'll do well. You never know the circumstances of those that are complaining...are they inactive, overweight, mind set, did they do PT, was their surgeon a good one, etc.

I have six levels of my spine fused....C3-4 from Ankylosing Spondylitis, C5-T1 mechanically fused and L4-s1 mechanically fused. When I tell people, they always say they would never have known.
 
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Aloha Bio,

Good to hear from you brother:headbang:

The beating I took did not induce new stenosis related issues. As you have stated stem cell and exosome procedures have not reversed spinal stenosis.

Based on my increased lumbar spinal instability issues and my new MRI report which details significant and recent wearing out of the discs, I am going full in with these regenerative protocols.

The surgeon who operated on me in 2015, who was also my doc when I went through a rupture at L-5/S-1, and a previous annular tear at 4-5, told me after the surgery, at some point I will need a fusion. Though my spine presents a unique challenge, as I have no lower stable segment to fuse to..

Anyway, I have nothing to lose, and everything to gain with these procedures.

Consult and comprehensive evaluation tomorrow. Then schedule it asap.

V
 
Viking I'm confused. You had surgery for stenosis and then re-injured your back. You didn't state what the re-injury is. The study refers to degenerative disc. You haven't mentioned that about yourself and DD is not an injury, it's something that happens to a lot of people over time. Like I said before, stem cell therapy can't repair stenosis. Viking what else is wrong with your back that you think stem cells might help? BTW, I have had back/spine issues for 33 years, so I feel your pain and I hope that you get the relief you're looking for!!

upeccmi stem cells won't help your stenosis. Stem cells don't dissolve bone (calcification). I read the horror stories online before my first fusion surgery. My spine specialist assured me that the people who have had successful surgery are out living their life, not posting. My fusion surgeries have been incredibly helpful! Don't be afraid to get them if you need to. They're not as debilitating as some make it out to be. If you're healthy and active, you'll do well. You never know the circumstances of those that are complaining...are they inactive, overweight, mind set, did they do PT, was their surgeon a good one, etc.

I have six levels of my spine fused....C3-4 from Ankylosing Spondylitis, C5-T1 mechanically fused and L4-s1 mechanically fused. When I tell people, they always say they would never have known.


Wow, 6 levels, God bless you!
They wanted to do L 3,4,5 fusion. As you, I hear lots of horror stories and with the lack of pain pills available any longer, I opted to live with the instability. I actually sway and walk drunk due to my back. My pain is low now but I can't over stress the area. When I do physical work, I need to stop after a short time.
 
As you, I hear lots of horror stories and with the lack of pain pills available any longer,

No joke this is. My father is in a lot of bad pain with sciatica now and who knows what in his low back. He went today to see an orthopedic doctor and he didn't do jack shit for my dad. Dad is 81 years old now. No cortisone shot and wouldn't write him a script for opiods. He reported his belief that my father has bad arthritis and told him to go see his family doctor for pain meds. Its like no doctors what to even prescribe it anymore, they are all in fear now of the government/law.
 
Prolozone Therapy

Aloha Maldorf,

Three weeks ago I saw an ND and received 1 series of prolozone injections for my lumbar spine-3-4-5-S-1.

Within 3 days, I was experiencing definite improvement with stability and less pain. Usual protocol is 3-5 prolotherapy injections. Usually a 3-4 week break between each series.

Switching gears to the stem cells and exosomes and additional methods that are utilized to facilitate a better response, in the clinic I've mentioned.

Would not hesitate to add prolozone therapy back in the mix.

V
 
No joke this is. My father is in a lot of bad pain with sciatica now and who knows what in his low back. He went today to see an orthopedic doctor and he didn't do jack shit for my dad. Dad is 81 years old now. No cortisone shot and wouldn't write him a script for opiods. He reported his belief that my father has bad arthritis and told him to go see his family doctor for pain meds. Its like no doctors what to even prescribe it anymore, they are all in fear now of the government/law.

Mal don't stop there. Do some research on spine specialists in and around your area. Pick a couple more and see how they treat him. He needs an MRI to know what's going on. A lot of GP's won't prescribe pain meds. Your dad needs to go to a pain management doctor.

Tell them not to dismiss him because of his age. He's not ready to curl up and die. He needs help to get a better quality of life and HE NEEDS AN MRI!
 

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