If there were straight answers to everything bodybuilders would be a common occurrence in the general population, nobody would give us a second look.
There's too much individuality when it comes to human bodies. It's not like building an engine where step 1 --> step 2 --> step 3 --> engine works. Some guys do fine with high dosed gear, some don't. Sometimes it has to do with contents of the oil, sometimes it has to do with the individual. We're never going to get scientific studies on the proper way to do this stuff so we just trial and error it, note our findings, and continue forward.