The quote you just posted is an excerpt from a Saudi pilot study of 22 subjects completed in 2006 "Subcutaneous administration of testosterone. A pilot study report" by Abdullah M. Al-Futaisi, Ibrahim S. Al-Zakwani, Abdulaziz M. Almahrezi, and David Morris (1) (see ref link below)
I saw two additional studies that also showed comparable plasma testosterone levels and E2 concentrations however the studies were conducted on a few hypogonadal males with most of the subjects women in M2F transition. There can be no ideal comparison because they were not given daily but rather weekly injections and obviously the female physiology in aromatization of T is going to create far different plasma profiles vs males.
The only thing I found recent, specifically on TRT was with hypogonadal males but unfortunately was conducted using testosterone undecanoate at it's standardized dose of 1000mg (4ml) in caster oil given in a single dose and T levels were tested at one, two, and three months. T remained elevated up to 2 months however was vague what elevated meant. What I want to know is who can put 4cc's subq? That would have to be one thick fat layer.
The ones I referenced in my previous post above (or similar) all used IM administration. At the end of the TU im vs s.c. (subq) study in the above paragraph, the testosterone levels remained similar but when asked, 63% of the male subjects said they preferred IM and those that preferred SubQ was 26% while 11% had no preference. They concluded that while plasma concentration remained similar in most of the subjects, few preferred the SubQ method in terms of convenience. They also noted that at 24hrs post inj, subq had the highest incidence of pain and/or redness at the injection site. But with 4cc's I'm not surprised.
Prudence demands I personally stick with what I know works. If you want to do something where results are rather ambivalent, I say more power to you and if it works for you, it works for you. Excellent. Case closed. But there would have to very compelling benefits for me to move to daily oil injects.
It was interesting this was brought up. I would have liked to see nice benefits with subq. Maybe with TRT on the rise, more studies will be done in the coming years to justify such a shift. Has anyone tried TNE or aqueous micronized suspension subcutaneously? That might be an interesting 4 week experiment with baseline bloodwork, and at 2wk, and 4wk hormone panels. I'll even pitch in if someone wants to give it a go. I only have one amp of aqueous T suspension left that I was planning on using this friday leg day. It will not be subq.
REF:
(1)
Subcutaneous-administration of testosterone (a pilot study report)