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- Nov 15, 2006
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I'm going to quote macrophage69alpha on this question in regards to estrogen suppression comparisons:
I really doubt any drop in IGF from nolva will do much damage to those following the plans that many use
In regards to cholesterol, this will vary as well, but for the majority I have witnessed, Aromasin is more forgiving on the HDL levels. Arimidex will lower HDL for many, and Letrozole ill murder it...lol.
That being stated Paul Bunyan would be correct in that there is other factors involved in HDL/LDL fluctuations, primarily the type of AAS being used and diet, that will also effect HDL/cholesterol levels.
BMJ
when it comes to this comparison its more about type of estrogen suppression as opposed to "strength". Arimidex is a VERY potent sulfatase inhibitor, which inhibits estrone. It is a moderately strong aromatase inhibitor (weak as compared to aromasin or letrozole). This is fine for women with breast cancer who produce percentage wise very high levels of estrone (the weak estrogen), which can be converted to estradiol (the strong estrogen) via aromatase.
For men this is generally not very good, especially for men on TRT since sulfatase inhibitors have very little effect on exogenous testosterone. Actually its generally not a good thing since it nearly completely eliminates estrone, while still allowing estradiol. If you have a choice as a man, you want estrone (weak estrogen) with near total elimination of estradiol (strong). Aromasin does inhibit sulfatase, though to a lesser extent than the competitive inhibitors (dex and letro). They are both potent aromatase inhibitors and highly suppress estradiol. Since exogenous test converts to estradiol via aromatase, aromasin is much better suited.
I really doubt any drop in IGF from nolva will do much damage to those following the plans that many use
In regards to cholesterol, this will vary as well, but for the majority I have witnessed, Aromasin is more forgiving on the HDL levels. Arimidex will lower HDL for many, and Letrozole ill murder it...lol.
That being stated Paul Bunyan would be correct in that there is other factors involved in HDL/LDL fluctuations, primarily the type of AAS being used and diet, that will also effect HDL/cholesterol levels.
BMJ