Whats tt ? Never heard of it...... I just thought adding a test booster to the Nolva would help things out, sense thats what im trying to do is boost my natural test back up, i would never even think about running just some otc for pct, i just thought that it might aid a little in what im trying to do.... Clomid is not a Must.... from my understanding most people choose nolva over clomid, its stronger on a mg per mg basis, doesnt cause the blurry vision and depression isnt an issue...... Forklift needs to do more research....
Nolva/HCG would certainly work for PCT but in my opinion not as well as aromasin/clomid/HCG. First off, unless you're using a suicidal inhibitor during cycle, you've still got a ton of estrogen floating around in your system. Why not run a suicidal AI during PCT also, all but eliminating the possibility of rebound gyno? Clomid is weaker mg for mg than nolva, you are correct, but clomid stimulates LH/FSH production which quickly elevates natural test production and can help mitigate losses coming off cycle.
Clomiphene Citrate Effects on Testosterone/Estrogen Ratio in Male Hypogonadism
Ahmad Shabsigh, MD 1 , Young Kang, MD 1 , Ridwan Shabsign, MD 1 , Mark Gonzalez, MD 1 , Gary Liberson, MD 1 , Harry Fisch, MD 1 , and Erik Goluboff, MD 1
1 Department of Urology, NY Presbyterian Medical Center, New York, NY, USA
Correspondence to Harry Fisch, MD, 944 Park Ave, New York, NY 10020, USA. Tel: 212-879-0800; Fax: 212-988-1634; E-mail:
[email protected]
Copyright Blackwell Publishing Ltd 2005
ABSTRACT
Aim. Symptomatic late-onset hypogonadism is associated not only with a decline in serum testosterone, but also with a rise in serum estradiol. These endocrine changes negatively affect libido, sexual function, mood, behavior, lean body mass, and bone density. Currently, the most common treatment is exogenous testostosterone therapy. This treatment can be associated with skin irritation, gynecomastia, nipple tenderness, testicular atrophy, and decline in sperm counts. In this study we investigated the efficacy of clomiphene citrate in the treatment of hypogonadism with the objectives of raising endogenous serum testosterone (T) and improving the testosterone/estrogen (T/E) ratio.
Methods. Our cohort consisted of 36 Caucasian men with hypogonadism defined as serum testosterone level less than 300 ng/dL. Each patient was treated with a daily dose of 25 mg clomiphene citrate and followed prospectively. Analysis of baseline and follow-up serum levels of testosterone and estradiol levels were performed.
Results. The mean age was 39 years, and the mean pretreatment testosterone and estrogen levels were 247.6 ± 39.8 ng/dL and 32.3 ± 10.9, respectively. By the first follow-up visit (4–6 weeks), the mean testosterone level rose to 610.0 ± 178.6 ng/dL (P < 0.00001). Moreover, the T/E ratio improved from 8.7 to 14.2 (P < 0.001). There were no side effects reported by the patients.
Conclusions. Low dose clomiphene citrate is effective in elevating serum testosterone levels and improving the testosterone/estadiol ratio in men with hypogonadism. This therapy represents an alternative to testosterone therapy by stimulating the endogenous androgen production pathway. Shabsigh A, Kang Y, Shabsign R, Gonzalez M, Liberson G, Fisch H, and Goluboff E. Clomiphene citrate effects on testosterone/estrogen ratio in male hypogonadism. J Sex Med 2005;2:716–721.
Note the small dosages in the study above...25/mg daily. During PCT it's recommended to go (daily during these weeks) 100/100/100/50/50/50mgs daily. This in conjunction with HCG will cause the fastest rise in natural testosterone production.... Clomid FTW!