I was thinking of ordering some along with an order for Boladrol but while Google'ing epistane I came across this article from Ergo-log.com
Wrong steroid in IBE’s Epistane
There’s something not quite right about IBE’s designer supplement Epistane. According to an article by Japanese doping hunters working for Mitsubishi Chemical Medience Corporation, published in Drug Testing & Analysis, at least one batch of the preparation contains a different steroid from the one listed on the label.
Epistane is supposed to contain the designer steroid 17alpha-methyl 2alpha,3alpha-epithio 5alpha-androstane-17-beta-ol. This steroid goes by the names of 17alpha-methylepithiostanol or methylepithiostanol. In 2007 methylepithiostanol appeared on the grey market.
When we looked it up in Julius Vida’s steroids bible Androgens and Anabolic Agents (1969) we found impressive data based on animal studies, which you can see below. The upper steroid is methylepithiostanol, which is what Epistane is supposed to contain.
VP = effect on the prostate; SV = effect on the sperm vesicles; LA = effect on the sphincter muscle. VP and SV are markers for masculinising side effects; LA is a marker for the desired muscle building effect. The values are compared with methyl testosterone, which was adjusted to 100.
As you can see, methylepithiostanol is a fantastic oral steroid with few side effects and a huge anabolic effect. So it’s a shame that it’s not in Epistane. At least, it’s not in Lot 105284 of IBE’s Epistane. Instead, the researchers found 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane 17beta-ol in the capsules. The difference is in the spatial position of the sulphur atom: In the steroid that the researchers found the sulphur atom hangs at the bottom of the steroid skeleton. But Epistane should contain a compound in which the sulphur atom is at the top of the steroid skeleton.
The performance of the steroid in Epistane is shown in the second row of the table above, and it’s not very impressive.
The researchers are not 100% sure of their case. They used NMR to find out whether they were dealing with 17alpha-methyl 2alpha,3alpha-epithio 5alpha-androstane-17beta-ol, or with 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane-17beta-ol. The Japanese used data from a 1975 study to interpret the results of their own measurements. But if the older study is not correct, the Japanese study isn’t either.
What’s more, the researchers found another substance in the capsules as well: the designer steroid 17alpha-methyl 5alpha-androst-2-en-17beta-ol. You may know this steroid under another name: madol, DMT, desoxymethyl testosterone or PheraPlex. This steroid’s performance is shown at the bottom of the table above. It’s just as good as methylepithiostanol.
The researchers think that madol is released when methylepithiostanol is manufactured. In the human body methylepithiostanol is converted into madol. The researchers gave human subjects IBE's Epistane, and found no traces of methylepithiostanol in their urine – but they did find madol. [This conversion apparently did not go so well in the rodents that Vida used – Ed.] So the contamination isn’t that bad.
According to the values from the table in Vida, it seems that madol may be even stronger than methylepithiostanol. So even if they take the wrong Epistane, users still stand to grow.
A modest discussion on the Japanese publication has arisen on bodybuilding.com. See here.
Whether the other Epistane products on the market, like Havoc, Epithin-E, Methyl-E, Hemaguno, Oxydrol, Kryptonite, Epidrol, Hemobolin, Epi-Max, Epiotren, CynergE, E-Stane, SuprEmacy, Jacked and Spawn, also contain the wrong methylepithiostanol it’s not possible to say on the basis of this research.
Source:
Drug Test Anal. 2009 Nov; 1(11-12): 518-25.
More:
Black market steroids: orals ok, injectables definitely not ok 30.08.2009
Dietary supplements containing sibutramine claim victims 19.04.2009
Lab test: Gaspari’s Orastan-A contains wrong steroids 05.01.2009
StarCaps diet pills contain diuretic bumetanide 04.11.2008
Weight loss supplement Anabolic Burner contains clenbuterol 28.10.2008
Lab tests: Furaguno and Oxyguno 24.09.2008
Methoxy-TST = Methoxy-TRN 22.09.2008
Anybody still using Epistane? If so what type results did you get? Better, same, or less than what you can get from 50-60mg/day of Anavar or T-Bol? Basically is it worth it?
Thanks
Wrong steroid in IBE’s Epistane
There’s something not quite right about IBE’s designer supplement Epistane. According to an article by Japanese doping hunters working for Mitsubishi Chemical Medience Corporation, published in Drug Testing & Analysis, at least one batch of the preparation contains a different steroid from the one listed on the label.
Epistane is supposed to contain the designer steroid 17alpha-methyl 2alpha,3alpha-epithio 5alpha-androstane-17-beta-ol. This steroid goes by the names of 17alpha-methylepithiostanol or methylepithiostanol. In 2007 methylepithiostanol appeared on the grey market.
When we looked it up in Julius Vida’s steroids bible Androgens and Anabolic Agents (1969) we found impressive data based on animal studies, which you can see below. The upper steroid is methylepithiostanol, which is what Epistane is supposed to contain.
VP = effect on the prostate; SV = effect on the sperm vesicles; LA = effect on the sphincter muscle. VP and SV are markers for masculinising side effects; LA is a marker for the desired muscle building effect. The values are compared with methyl testosterone, which was adjusted to 100.
As you can see, methylepithiostanol is a fantastic oral steroid with few side effects and a huge anabolic effect. So it’s a shame that it’s not in Epistane. At least, it’s not in Lot 105284 of IBE’s Epistane. Instead, the researchers found 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane 17beta-ol in the capsules. The difference is in the spatial position of the sulphur atom: In the steroid that the researchers found the sulphur atom hangs at the bottom of the steroid skeleton. But Epistane should contain a compound in which the sulphur atom is at the top of the steroid skeleton.
The performance of the steroid in Epistane is shown in the second row of the table above, and it’s not very impressive.
The researchers are not 100% sure of their case. They used NMR to find out whether they were dealing with 17alpha-methyl 2alpha,3alpha-epithio 5alpha-androstane-17beta-ol, or with 17alpha-methyl 2beta,3beta-epithio 5alpha-androstane-17beta-ol. The Japanese used data from a 1975 study to interpret the results of their own measurements. But if the older study is not correct, the Japanese study isn’t either.
What’s more, the researchers found another substance in the capsules as well: the designer steroid 17alpha-methyl 5alpha-androst-2-en-17beta-ol. You may know this steroid under another name: madol, DMT, desoxymethyl testosterone or PheraPlex. This steroid’s performance is shown at the bottom of the table above. It’s just as good as methylepithiostanol.
The researchers think that madol is released when methylepithiostanol is manufactured. In the human body methylepithiostanol is converted into madol. The researchers gave human subjects IBE's Epistane, and found no traces of methylepithiostanol in their urine – but they did find madol. [This conversion apparently did not go so well in the rodents that Vida used – Ed.] So the contamination isn’t that bad.
According to the values from the table in Vida, it seems that madol may be even stronger than methylepithiostanol. So even if they take the wrong Epistane, users still stand to grow.
A modest discussion on the Japanese publication has arisen on bodybuilding.com. See here.
Whether the other Epistane products on the market, like Havoc, Epithin-E, Methyl-E, Hemaguno, Oxydrol, Kryptonite, Epidrol, Hemobolin, Epi-Max, Epiotren, CynergE, E-Stane, SuprEmacy, Jacked and Spawn, also contain the wrong methylepithiostanol it’s not possible to say on the basis of this research.
Source:
Drug Test Anal. 2009 Nov; 1(11-12): 518-25.
More:
Black market steroids: orals ok, injectables definitely not ok 30.08.2009
Dietary supplements containing sibutramine claim victims 19.04.2009
Lab test: Gaspari’s Orastan-A contains wrong steroids 05.01.2009
StarCaps diet pills contain diuretic bumetanide 04.11.2008
Weight loss supplement Anabolic Burner contains clenbuterol 28.10.2008
Lab tests: Furaguno and Oxyguno 24.09.2008
Methoxy-TST = Methoxy-TRN 22.09.2008
Anybody still using Epistane? If so what type results did you get? Better, same, or less than what you can get from 50-60mg/day of Anavar or T-Bol? Basically is it worth it?
Thanks