AAS impact on lipids- constant, progressive or dose dependent?

[OldManLogan]

Generally speaking, if one keeps a particular AAS dosage long term, is the impact on lipids also the same over time?

So, hypothetically - let’s say someone does a long 20 week cycle, and after the cycle serum concentration is stable at say week 4, and their lipids are affected a certain way, does that effect on lipids stay the same as long as the dosage also stays the same? Or do the lipids continue to worsen or get affected more and more as time goes by, even when the AAS dosages do not change?

 

[Astro95]

Hard to answer because your lipid profile is affected by other variables besides gear. Diet and exercise (cardio) being major drivers as well as supplementation.

 

[neutrino]

Too many variables to provide anywhere near an accurate answer.

-genetics
-stress
-diet
-activity levels (especially cardio)
-type of compounds
-dosage of compounds

But more than likely not. If you are redlining your car, its not like the damage/wear on the engine stops as soon as you redline...it continues to cause damage the whole time that you are redlining. That's why we take bloods at the end of a cycle: to see how bad things got. When you reach serum concentration levels the damage is far from having peaked - it is only the beginning.

 

[OldManLogan]

Too many variables to provide anywhere near an accurate answer.

-genetics
-stress
-diet
-activity levels (especially cardio)
-type of compounds
-dosage of compounds

But more than likely not. If you are redlining your car, its not like the damage/wear on the engine stops as soon as you redline...it continues to cause damage the whole time that you are redlining. That's why we take bloods at the end of a cycle: to see how bad things got. When you reach serum concentration levels the damage is far from having peaked - it is only the beginning.

Actually, you said something that clicked in my head- even removing all the other factors at play- even if you maintain a steady dosage, that dosage by itself is steadily affecting you- so over time- EVEN WITHOUT A DOSAGE INCREASE- it is steady and cumulative wear and tear on your body.

That’s exactly the “a ha!” Moment I was looking for.

 

[Astro95]

Actually, you said something that clicked in my head- even removing all the other factors at play- even if you maintain a steady dosage, that dosage by itself is steadily affecting you- so over time- EVEN WITHOUT A DOSAGE INCREASE- it is steady and cumulative wear and tear on your body.

That’s exactly the “a ha!” Moment I was looking for.

You still didn’t get it. All the other factors help or hurt the lipid profile. You’re still focused only on the aas dosage. The dose could stay the same and good supplementation, nutrition and exercise could completely fix your somewhat skewed lipid profile. Where at the same time the dose could stay the same and all those factors pushed in a negative direction worsen your lipids.

 

[OldManLogan]

You still didn’t get it. All the other factors help or hurt the lipid profile. You’re still focused only on the aas dosage. The dose could stay the same and good supplementation, nutrition and exercise could completely fix your somewhat skewed lipid profile. Where at the same time the dose could stay the same and all those factors pushed in a negative direction worsen your lipids.

Actually I did get it, I understood the other factors piece- I just needed to understand how that one particular vector works by itself.
Very clear on the effects proper supplementation, diet, ancillaries etc all work together for the final combined result.
Thanks for the info!!!

 

[buck]

For me at the same dose and other things being the same my lipid levels stay about the same. Of course as the years go by that can change as the body does not stay the same.

 

[neutrino]

For me at the same dose and other things being the same my lipid levels stay about the same. Of course as the years go by that can change as the body does not stay the same.

genetics baby. Ive never seen my HDL drop below 38 no matter how big of a cycle, how little or much cardio, how good or shitty diet, orals, etc. Yet some people struggle to maintain that level naturally. Its just how it is. Life aint fair and we are all dealt different hands

 

[buck]

genetics baby. Ive never seen my HDL drop below 38 no matter how big of a cycle, how little or much cardio, how good or shitty diet, orals, etc. Yet some people struggle to maintain that level naturally. Its just how it is. Life aint fair and we are all dealt different hands

Back when i was a kid in my 30's and 40's things were different. Now that i am an old man in my 60's. Things are different. My total cholesterol can change up to 20 points. Didn't used to be that way. The highest total cholesterol i have ever has was 159 and the lowest 130. I have away had lower cholesterol. And spent years to no avail trying to get it up as longevity studies point to low cholesterol having shorter life spans. But i have always ate well did some aerobics since the 1970's

 

[neutrino]

Back when i was a kid in my 30's and 40's things were different. Now that i am an old man in my 60's. Things are different. My total cholesterol can change up to 20 points. Didn't used to be that way. The highest total cholesterol i have ever has was 159 and the lowest 130. I have away had lower cholesterol. And spent years to no avail trying to get it up as longevity studies point to low cholesterol having shorter life spans. But i have always ate well did some aerobics since the 1970's

Shit man I'm in my 30s and I feel "old". Calling my age group kids made me feel good

 

[Pheedno]

Every answer is a guess and an anecdotal post mortem of the time spent. Then you have memory of what choices outside of that variable were consumed.
I haven't competed in 15 years. Haven't been above 300mg of test in years. Probably lost 20lbs of tissue over time.
I've had lipids in horrible condition(HDL in teens/LDL 180's) and egfr in bad condition(67) when pushing a dose. Doses up to 2g a week, shit loading, dirty bulking, etc.
My lipids now are in the 70's on LDL and 40's-60's HDL. My egfr is 99 and cystatin C(no one tested that in the early 2000's) is .67
I did come out with a 230 CAC score. How did all that change? Who knows. Genetics, wisdom over time to mitigate a side effect when you see it coming(or opposite), loss of body weight/tissue. ???
Good idea but you'll likely be massaging the topic and not delineating anything from it

 

[drafty_c]

Generally speaking, if one keeps a particular AAS dosage long term, is the impact on lipids also the same over time?

So, hypothetically - let’s say someone does a long 20 week cycle, and after the cycle serum concentration is stable at say week 4, and their lipids are affected a certain way, does that effect on lipids stay the same as long as the dosage also stays the same? Or do the lipids continue to worsen or get affected more and more as time goes by, even when the AAS dosages do not change?

That is a solid question that often gets overlooked in favor of just looking at "peak" numbers. In theory, once your serum levels stabilize, you would expect the impact on HDL and LDL to reach a plateau. However, the biological reality is often more complex because the body isn't a closed system.