This is Something I have a lot of experience with ,, I have been on an off accutane for years ..
If you want to clear it up completely,, you need to take between .75 and 1 mg per kg (2.2lbs) of bodyweight for 12 weeks,,
so if you weigh 200lbs,, you need 100mg's per day ,,
The Sides are heavy at those doses --- Cracked lips ,, Blood noses ,, Depression,,, so some guys keep it low at around 40mg's per day,, but it is not always completely effective at those doses.
It will affect your liver ,,and your cholesterol levels,, you should have your liver enzymes,, and cholesterol tested every month if you are on accutane and a cycle ..
I have found that Legalon (silymarin) at 400mg's per day keeps my liver in tip top shape ,, even while on accutane dbol and winny.
If you are gonna do accutane ,, it MUST be gelcaps,, Isotretinoin reacts with oxygen and degrades ,, so if it' not in GELCAP it won't be effective