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Acetate and Enanthate Esters and Oral Bioavailabilty

K80

New member
Newbies
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Jun 13, 2008
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Hi fellas,

I'm in the process of planning my next cycle and it will be the first in which I intend to include orals, but my understanding of biochemistry is extremely limited (as you will see :) ) so I have quick question for the more learned - Does the addition of certain esters effect the bioavailabilty of methylated compounds? More specifically; is Primo enanthate, taken orally, as effective as Primo acetate?

Cheers guys
 
I beleive in regards to Primobolan (Methenolone) the tabs are the Acetate and the Primo-depot (Inj)
is the enanthate.

I do agree with Vadim though for the most part he is correct Imo.
 
As to me Primo enanthate (taken orally) is more effective then Primo acetate. Either of them is not so effective if taken orally of coz. Take injectible forms!:)
 
Here is a little clip I found just from a quik google search that may help explain better. From wikipedia-
___________________________
Methenolone enanthate, or methenolone enanthate, is a dihydrotestosterone (DHT) based anabolic steroid. It is an ester derivative of methenolone sold commonly under the brand names Primobolan (tablet form) or Primobolan Depot (injectable). When it interacts with the aromatase enzyme it does not form any estrogens. It is used by people who are very susceptible to estrogenic side effects, having lower estrogenic properties than nandrolone. Methenolone, in form of enanthate and acetate, is available as an injection or as an oral respectively. The injection is naturally regarded as having a higher bioavailability. It is an enanthate ester which is quite long-acting. Because it by-passes hepatic breakdown on the first pass, it also has a higher survival rate. The tablets are in a short-lived acetate form. Methenolone is not 17-alpha-alkylated, but 1-methylated for oral bioavailability. This reduces the stress on the liver, but also the availability. It is considered one of the safer steroids, meaning it has few side effects.
 
I know taking 50-100mg of boldenone acetate orally a few hours before training has a hell of a greater affect than at any point on a cycle of boldenone undecylenate at 400mg/wk.

100mg ends up stopping me training due to the insane pump of it.
 
Primobolan tabs are (were) very effective when take orally.
Higher dosages are needed.
It was very popular in the 70's 80's and 90's till the mexican and european scenes died down.
As Bill Roberts said and I quote as it is pretty much well known but forgotten on the new age of bb boards:
Methenolone Acetate

by Bill Roberts - All else being equal, methenolone acetate is an excellent oral steroid drug. Unlike most other orals, it is not 17-alkylated and does not have liver toxicity problems. It is perhaps only half as potent by the oral route as by injection, so dosages need to be high, at least 100 and preferably 200-300 mg per day, but if that can be afforded it is an excellent drug. It is unusual among oral steroids as being Class I, binding well to the androgen receptor.

The problem is that Mexican Primobolan tablets are simply too expensive per milligram, and too few mg per tablet, to be practical for a male bodybuilder. In some European countries, however, 50 mg tablets are available at a reasonable price, and are a good buy for those who can obtain them.

The claim, however, that methenolone acetate tablets help burn fat, as a result of being acetate esters, is purely a myth. The compound has the same LBM-sparing properties when dieting as does injected Primobolan, which is to say, it is quite useful if dosage is sufficient.

For females, dosage should not in my opinion exceed 30 mg/day, and even this may cause irreversible virilization problems. If a woman must try steroids, 5 mg of methenolone acetate twice per day would be a reasonable starting point, if modest results are acceptable.

Methenolone acetate is the chemical name of active ingredient in Primobolan Tablets. Primobolan was a registered trademark of Schering AG in the United States and/or other countries prior to cancellation."


The preferred method would be injection but many still take the tabs when they can get them.

Same with Tren Acetate-many used to "eat" the pellets and get decent gains it was expensive and high dosed but I knew many a guy that got good results taking finaplix pellet sublingually. Huge threads and debates back in the days on UG Bolex Renegade etc.

A guy I knew that did a fed stint for AAS in the late 90's said the main AAS the guys used was fina pellets smuggled in and they all made good gains.

Again the injection route is more cost effective and potent method/means of delivery but they are not inert or ineffective or worthless orally.
 

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