" a lot of Tren Ace's benefits come from the fact it prevents de novo lipogensis when in a low/no estrogen environment "[/QUOTE]
Why this brotastic shit gets repeated all over the internet is a mystery to me.
There isn't even a study showing trenbolone inhibiting DNL in bovines, much less in man. This is a brotastic extrapolation based on the fact that inclusion of estrogenic compounds alongside tren enhances weight and fat gain in feedlot heifers.
There are plenty of possibilities other than influencing DNL to explain this. Ever witness a female go through puberty and suddenly gain tits, ass, and possibly even stretch marks on the thighs from the rapid weight - mostly fat - gain? Ever witness a female "lose her curves" when going through menopause without HRT? Yeah, this has dick to do with DNL.
DNL is a major pathway in ruminants. Cows have four stomachs and are built to efficiently convert cellulose into hundreds of pounds of fat and muscle tissue. Sound anything remotely like a human?
DNL is a minor pathway in humans which is rarely relevant to bodybuilders. When you are dieting in a deficit, DNL simply doesn't happen. And shutting down DNL during acute carbohydrate overfeeding - what the rest of the article describes - is asinine. The body switches on DNL when hepatic and muscle glycogen are capped and oxidation rates are at maximum - it is either DNL or hyperglycemia (re: organ damage and death) at that point.