The liver? I dunno. People can get away with a lot of orals anymore. I'm not sure everyone experiences serious damage. A jaundiced liver from alcohol is probably a lot worse.
It's amazing how few cases there are of jaundice etc considering the doses people use, like 100mg of Winny or Var seems not crazy in threads here, no one bats an eye.
Peliosis hepatitis might be more common, we've had a few on this forum, but it may not cause symptoms so undiagnosed. Some of us might have them without knowing.