• All new members please introduce your self here and welcome to the board:
    http://www.professionalmuscle.com/forums/showthread.php?t=259
Buy Needles And Syringes With No Prescription
M4B Store Banner
worldofroids
Riptropin Store banner
Generation X Bodybuilding Forum
Buy Needles And Syringes With No Prescription
Buy Needles And Syringes With No Prescription
Mysupps Store Banner
IP Gear Store Banner
Anabolic Hormones Store Banner
Ganabol Store Banner
Spend $100 and get bonus needles free at sterile syringes
Professional Muscle Store open now
mckee
PHARMAHGH1
Bruce Labs Store banner
gd
Professional Muscle Store open now
over 5000 supplements on sale at professional muscle store
roids-210x65-48kb-1
granabolic123
napsgear-210x65
advertise1
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
advertise1
PM-Ace-Labs
advertise1
kinglab
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store

Berberine Metformin Don’t Hate

suppdude

Well-known member
Kilo Klub Member
Registered
Joined
May 1, 2016
Messages
1,735
Yes, I know another met berb thread. Different though.

Running metformin, no gi issues, no shits, no bloating, no gas, nothing.

Running berberine, gi issues, shits like you wouldn’t believe, bloating, gas, all the sides.

Running metformin and berberine together, no issues that I can remember.

I switched to berberine due to mike Arnold recommendation. But I’m going to go back to metformin at 1g per day.

I know many get the sides from one of the other, so curious on others thoughts.

Also, if running slin, are you fellas running metformin on slin days or on off days only and only using insulin sensitizers? Slin 5x a week.


Sent from my iPhone using Tapatalk
 

heavyhitter

Featured Member / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Joined
Sep 12, 2004
Messages
7,483
Berberine doesn't bother me any that ive noticed. But metformin absolutely crushes my appetite, I get gassy and bloated beyond belief and it makes it incredibly difficult to eat. Personally when running slin I use it 3-4 days a week for lagging bodyparts and I run insulin sensitizers on off days as well as everyday once I stop the insulin
 

epoxy

Well-known member
Kilo Klub Member
Registered
Joined
Apr 21, 2009
Messages
2,993
Yes, I know another met berb thread. Different though.

Running metformin, no gi issues, no shits, no bloating, no gas, nothing.

Running berberine, gi issues, shits like you wouldn’t believe, bloating, gas, all the sides.

Running metformin and berberine together, no issues that I can remember.

I switched to berberine due to mike Arnold recommendation. But I’m going to go back to metformin at 1g per day.

I know many get the sides from one of the other, so curious on others thoughts.

Also, if running slin, are you fellas running metformin on slin days or on off days only and only using insulin sensitizers? Slin 5x a week.


Sent from my iPhone using Tapatalk

honestly after a year of running berberine i think over time you need to continue using more and more. i ran out a couple months ago due to money constraints at the time and i actually feel much better and less bloated/gassy than i used to - and i didn't see the corrolation until after i stopped it because i was attributing it to other things. moving forward i would likely just stick to metformin because it's cheaper and better.
 

Feeshoils

Member
Registered
Joined
Dec 11, 2012
Messages
177
Ive read a few articles studying the effect that both metformin and berberine have on the gut microbiome.

It's possible that berberine alone might have more of an adverse effect on the microbiome of an individual (more than metformin) or vice versa in your experience.
Everybody has a microbiome that is different due to many factors, hence the bloating, gas and shits that some experience on either metformin or berberine.

Metformin is fine for me in lower doses under 500mg/day any more and ill be strapped to the toilet all day. Berberine however, I can take 2-3g a day with no issues at all. Yet to try them together though.

Very interesting topic!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411811/

https://microbiomemastery.com/microbiome-update-2-berberine-affect-microbiome/


https://www.longecity.org/forum/topic/85835-berberine-gut-flora-and-probiotics/
"Accumulating evidence suggests that the gut microbiota is an important factor in mediating the development of obesity-related metabolic disorders, including type 2 diabetes. Metformin and berberine, two clinically effective drugs for treating diabetes, have recently been shown to exert their actions through modulating the gut microbiota. In this study, we demonstrated that metformin and berberine similarly shifted the overall structure of the gut microbiota in rats. Both drugs showed reverting effects on the high-fat diet-induced structural changes of gut microbiota. The diversity of gut microbiota was significantly reduced by both berberine- and metformin-treatments. Nearest shrunken centroids analysis identified 134 operational taxonomic units (OTUs) responding to the treatments, which showed close associations with the changes of obese phenotypes. Sixty out of the 134 OTUs were decreased by both drugs, while those belonging to putative short-chain fatty acids (SCFA)-producing bacteria, including Allobaculum, Bacteriodes, Blautia, Butyricoccus, and Phascolarctobacterium, were markedly increased by both berberine and, to a lesser extent, metformin. Taken together, our findings suggest that berberine and metformin showed similarity in modulating the gut microbiota, including the enrichment of SCFA-producing bacteria and reduction of microbial diversity, which may contribute to their beneficial effects to the host."
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,747
Yes, I know another met berb thread. Different though.

Running metformin, no gi issues, no shits, no bloating, no gas, nothing.

Running berberine, gi issues, shits like you wouldn’t believe, bloating, gas, all the sides.

Running metformin and berberine together, no issues that I can remember.

I switched to berberine due to mike Arnold recommendation. But I’m going to go back to metformin at 1g per day.

I know many get the sides from one of the other, so curious on others thoughts.

Also, if running slin, are you fellas running metformin on slin days or on off days only and only using insulin sensitizers? Slin 5x a week.


Sent from my iPhone using Tapatalk

What was the basis for Mike suggesting you switch from Metformin to Berberine?
 

suppdude

Well-known member
Kilo Klub Member
Registered
Joined
May 1, 2016
Messages
1,735
What was the basis for Mike suggesting you switch from Metformin to Berberine?



I can’t recall of the top of my head but he used to recommended metformin with his slin protocol then switched to recommending berberine. I believe it was due to mtor and igf along with a few other reasons. It’s in a thread somewhere regarding his protocol.

I believe him and Stewie went back and forth for a while in the thread about the topic.


Sent from my iPhone using Tapatalk
 

joos23

Sponsor Rep
Kilo Klub Member
Registered
Joined
Jan 24, 2009
Messages
2,491
How are you guys using berberine?
 

IronLion2

Banned
Joined
Nov 10, 2017
Messages
1,802
I like using berb far away from my workouts, ASAP in the morning and right before bed, it's my goal to improve AMPK while my body's in a fasted state.
 

nylifter727

Member
Registered
Joined
Jul 24, 2010
Messages
61
I take berberine with my two carb meals which are pre and post. 500mg each time.

I will say I haven't tested my BG with and without taking it and I've been meaning to so I can see how effective it actually is.
 

RamboStallone

Featured Member/Kilo Klub
Featured Member
Kilo Klub Member
Registered
Joined
Jul 2, 2014
Messages
7,233
Yes, I know another met berb thread. Different though.

Running metformin, no gi issues, no shits, no bloating, no gas, nothing.

Running berberine, gi issues, shits like you wouldn’t believe, bloating, gas, all the sides.

Running metformin and berberine together, no issues that I can remember.

I switched to berberine due to mike Arnold recommendation. But I’m going to go back to metformin at 1g per day.

I know many get the sides from one of the other, so curious on others thoughts.

Also, if running slin, are you fellas running metformin on slin days or on off days only and only using insulin sensitizers? Slin 5x a week.


Sent from my iPhone using Tapatalk
Berberine is shit, gave me nothing but issues. On the other hand, Metformin is the real deal, on it now. Works great! It made me more vascular and leaner/fuller as I was getting a bit soft being on just TRT.

I had soo much pain on the toilet with berberine, it felt like shitting hot lava. Major GI issues. Hated it and didn't see the benefits like I do with metformin.
 

roasthawg

New member
Newbies
Joined
Dec 18, 2014
Messages
37
Taking 500mg berberine 3x a day has brought my fbg down from an average of 106 to an average of 90. No unwanted sides for me.

Sent from my SM-G955U using Tapatalk
 

suppdude

Well-known member
Kilo Klub Member
Registered
Joined
May 1, 2016
Messages
1,735
Berberine is shit, gave me nothing but issues. On the other hand, Metformin is the real deal, on it now. Works great! It made me more vascular and leaner/fuller as I was getting a bit soft being on just TRT.

I had soo much pain on the toilet with berberine, it felt like shitting hot lava. Major GI issues. Hated it and didn't see the benefits like I do with metformin.

Yeah I feel ya. From what I've seen, everyone experiences the two differently and one can typically run one or the other due to one of the two giving explosive poos.
 

Staff online

  • Big A
    IFBB PRO/NPC JUDGE/Administrator

Forum statistics

Total page views
513,119,150
Threads
126,089
Messages
2,470,793
Members
156,519
Latest member
Horsemanbaby
Top