Best environment for IGF-1 production

[ShZ]

Hey guys,

Can someone of you please list all the factors that play a role in IGF-1 production? Obviously growth hormone is required. Insulin, thyroid hormones and estrogen also play a role. But what else is required and how much of it? What hinders IGF-1 production? Would be great to have a picture of the perfect environment for it.

Thanks in advance!

 

[ShZ]

Bump

 

[Sevn]

Low total estrogen. High estrogen kills IGF levels, I've seen bloodwork confirming it.


Make sure you test for your TOTAL estrogen levels.

Sent from my SM-G950F using Professional Muscle mobile app

 

[goal245]

Healthy liver if you want to get the most conversion out of you exogenous gh.

Balanced estrogen

and

Don't overthink it

 

[ShZ]

Low total estrogen. High estrogen kills IGF levels, I've seen bloodwork confirming it.


Make sure you test for your TOTAL estrogen levels.

Sent from my SM-G950F using Professional Muscle mobile app

Estrogen really seems to play an important role. Thanks for the answer!

 

[ShZ]

Healthy liver if you want to get the most conversion out of you exogenous gh.

Balanced estrogen

and

Don't overthink it

Yeah definitly.

 

[ShZ]

How much insulin should be present ideally?

 

[ShZ]

Bump

 

[musclemoose]

Low total estrogen. High estrogen kills IGF levels, I've seen bloodwork confirming it.


Make sure you test for your TOTAL estrogen levels.

Sent from my SM-G950F using Professional Muscle mobile app

Agreed. And there is research that arimidex is better for igf-1 levels than the other anti-e's. In studies there was an actual increase in igf-1 on arimidex where as with the other anti-e's igf-1 stayed same or decreased. you can look on the articles forum and ive posted plenty of research there about why arimidex is king of all anti-e's.

"IGF-1 significantly increased during anastrozole treatment (baseline versus 12 weeks, P=0.031)"

https://www.ncbi.nlm.nih.gov/pubmed/11983488

 

[musclemoose]

Healthy liver if you want to get the most conversion out of you exogenous gh.

Balanced estrogen

and

Don't overthink it

Agreed. That is why i take 3g Betain Anhydrous (TMG) every day pre-workout. TMG supports a healthy liver. There are also studies of small increase in igf-1 production.

"Supplementation of betaine at 1.25g twice daily for one week appears to, when exercising in a fasted state, increase IGF-1 (7.8%) and reduce cortisol concentrations (6.1%) and nonsignificantly increase growth hormone (6.1%) relative to placebo."

"Supplementation of betaine at 500mg twice daily over the course of one year was able to fully normalize liver enzymes in three out of seven patients and reduce them by more than 50% in three others, with one nonresponder and the dropouts (before the year the trial lasted) also noting a 38-39% reduction."

 

[musclemoose]

Hey guys,

Can someone of you please list all the factors that play a role in IGF-1 production? Obviously growth hormone is required. Insulin, thyroid hormones and estrogen also play a role. But what else is required and how much of it? What hinders IGF-1 production? Would be great to have a picture of the perfect environment for it.

Thanks in advance!

Magnesium is very important as well. I take 500mg magnesium taurate or citrate daily.

Studies have shown that magnesium intake affects the secretion of total IGF-1 and increase testosterone bioactivity."

https://www.ncbi.nlm.nih.gov/pubmed/21675994