caffeine and its effects on urine output

[maza]

Hey boys.
Im not honestly a big water drinker, i have prob one cup of coffee in the morn. kidney function is fine
Now i undertand caffeine can act like a diuretic, but after a cup of coffee i non stop have to go to the toilet every hour to
do a wee for the next 12 hours
And im like thinking i hardly ate much or had much water to drink, where the hell is this urine coming from

Is the water being drawn out from intracelluar or extracelluar muscles/cells/spaces in the body?

In what pathways does caffeine increase diuresis?

Chime in if anyone experiences anything similar

 

[Josefein421]

Chime in if anyone has to pee after taking a substance with a diuretic effect? No, no one here has ever encountered such a phenomenon lol.

First, you admit you dont drink much water. You should worry more about fixing that than the mild diuretic effect of caffeine, which any dehydration would be mitigated by being adequately hydrated.

Second, he body is 60% water. Does the exact mechanism of action really make a difference to you?

Last, I hope it is a European thing or something otherwise an adult male saying he has to "wee" is wild lol.

TLR You're fine. Caffeine makes everyone pee. Drink more water.

 

[Stewie]

The urine is not coming from your muscles directly. It's from blood plasma and interstitial fluid. Caffeine blocks sodium (and water) reabsorption in the proximal tubule and loop of Henle via adenosine receptor blockade. This increases glomerular filtration rate plus inhibition of sodium reabsorption = peeing every hour.

Because you drank little water, your body has less of a buffer, so caffeine triggers a big diuresis wave that lasts as long as the caffeine is in your system. Which is whatever your specific metabolism rate is for caffeine.

What's the fix? Sip 500 +/- mL of water with your coffee/caffeine, this will blunt the pee storm you're pissing away

 

[maza]

The urine is not coming from your muscles directly. It's from blood plasma and interstitial fluid. Caffeine blocks sodium (and water) reabsorption in the proximal tubule and loop of Henle via adenosine receptor blockade. This increases glomerular filtration rate plus inhibition of sodium reabsorption = peeing every hour.

Because you drank little water, your body has less of a buffer, so caffeine triggers a big diuresis wave that lasts as long as the caffeine is in your system. Which is whatever your specific metabolism rate is for caffeine.

What's the fix? Sip 500 +/- mL of water with your coffee/caffeine, this will blunt the pee storm you're pissing away

thank you