Carbs with L-Carnitine a must?

[kscowboy]

Per another thread I started, I am running L-carnitine and having great results with the fat loss. I pin 300mg about 30 minutes before fasted morning cardio and another 300 about 30 minutes before weights in the afternoon. My morning dosage is without any food or carbs and its working but I am reading that it really works better when combined with carbs. Kinda defeats the fasted cardio part but if it works better, im not opposed to it. Do carbs help L-Carnitine work better or is that an old way of thinking? If so any help on the amount or protocol? Thanks for any help

 

[01dragonslayer]

If your protocol includes L-carnitine base injection research indicates that you generally need an insulin spike to effectively transport the L-carn into the skeletal muscle cell. While injecting L-carnitine increases its bioavailability significantly compared to oral at around 18%?? maybe....not too sure but close...it still requires insulin to facilitate its uptake from the blood into the muscle tissue.

 

[Heath82]

Just take a couple of ius of insulin

 

[luki7788]

You don't necessarily need carbs—just take a scoop of EAA (so you have about 2.5-3g of leucine) before your morning dose; the effect will be very similar. If you're familiar with L-carnitine's mechanism of action, you'll know why it works so well.

 

[Sully1234]

Am I the only one who doesn't really "feel" anything from Injectable L Carn?

I can take 500-800mg 30 mins pre workout and the endurance boost if there is not enough for me to notice.

This has happened with Synthetine and my own home made.

 

[Stewie]

Anything that initiates an insulinotropic response, should help shuttle (transport) carnitine.

Be cognizant that you may, or may not be taking something ______<- insert literally any compound– that may bastardize the primary solute protein carrier –OCT's. That was mentioned a time not so long ago in this this thread: https://www.professionalmuscle.com/...s/my-fascination-with-inj-l-carnitine.166391/

Your GLP-1RA-GIP and GH are mostly likely filling the gap without the worries of acute amino acids or carbs/insulin spike. Unless you're hyponatremic. Which would impair that fancy protein transporter –OCT's.

 

[Worldsfastestfatty]

Am I the only one who doesn't really "feel" anything from Injectable L Carn?

I can take 500-800mg 30 mins pre workout and the endurance boost if there is not enough for me to notice.

This has happened with Synthetine and my own home made.

I don't think there's any acute impact of l-carn - as in I don't, from my experience, think you necessarily need to pin it around the workout.

I use it with a substantial carb meal post workout and notice significant endurance increases in the faster cardio session after. Once it's loaded into the muscle it's there until you use it. My log book performance for endurance work confirms this.

 

[Stewie]

Try to get in sufficient amounts of choline enriched foods, e.g., eggs, organ meat, ect. Or you could supplement with choline bitartrate.

Purportedly helps maintain carnitine pools by-way of limiting excretion working in tandem with OCT's transporters. Or so the science says it does to maximize cellular uptake.

 

[kscowboy]

You don't necessarily need carbs—just take a scoop of EAA (so you have about 2.5-3g of leucine) before your morning dose; the effect will be very similar. If you're familiar with L-carnitine's mechanism of action, you'll know why it works so well.

Thanks Luki- so this morning I took 3g of Leucine about 30 minutes before my shot and went to do cardio about 30 minutes after that. Seemed to sweat more today and had good energy and endurance. You mentioned taking EAA but focused on the Leucine so that’s what I took. This seemed to make a difference vs taking nothing. Thanks again!!!

 

[luki7788]

Thanks Luki- so this morning I took 3g of Leucine about 30 minutes before my shot and went to do cardio about 30 minutes after that. Seemed to sweat more today and had good energy and endurance. You mentioned taking EAA but focused on the Leucine so that’s what I took. This seemed to make a difference vs taking nothing. Thanks again!!!

Yes, it was about leucine, it will give an insulin response, so you did everything right

 

[swm1972]

Am I the only one who doesn't really "feel" anything from Injectable L Carn?

I can take 500-800mg 30 mins pre workout and the endurance boost if there is not enough for me to notice.

This has happened with Synthetine and my own home made.

Only thing I have noticed is I sweat more and more easily... I am leaning out though with no real changes to diet.