Hey guys. I have been doing a lot of searching and have still yet to find a good answer for this question so I thought I would post it here.
I just started researching with a pre-workout insulin protocol similar to Milos/Mike Arnold's protocols (on my rat) and was curious how long I should wait to dose him with CJC/GHRP post insulin pin. I am researching 10IU Humulin R Intramuscularly @ around 10:00 AM and having him start his usual workout protocol @ 11:00 AM, usually ending around 12:30.
From what i have read, it seems that Humulin R IM onset is around 30 mins (seems to be accurate from observing my rat), peak around 2 hours, and 3-4 hours to clear the system
My main concern is insulin's suppression of growth hormone but the only article I could find was this Insulin suppresses growth hormone secretion by rat pituitary cells.
according to my probably flawed math, 0.7nM of insulin is 4065ng/mL or 4065ug/L aka 89IU/L
So .7nM of insulin inhibited Basal GH secretion by approx 50% (after 8 Days straight of exposure to exogenous insulin in a concentration of 4065ug/ml or 89IU/L)
assuming (again yell at me if my math is wrong) the human body has 5.6 L of blood, that would be roughly 500IU of circulating insulin....
Again I am not claiming this math is right and I want someone to check it for me but after reading that is there any reason to think that the doses we are researching with are anywhere close to enough to inhibit GH secretion? Obviously this is only 1 study but if anyone else has any info please chime in!
I just started researching with a pre-workout insulin protocol similar to Milos/Mike Arnold's protocols (on my rat) and was curious how long I should wait to dose him with CJC/GHRP post insulin pin. I am researching 10IU Humulin R Intramuscularly @ around 10:00 AM and having him start his usual workout protocol @ 11:00 AM, usually ending around 12:30.
From what i have read, it seems that Humulin R IM onset is around 30 mins (seems to be accurate from observing my rat), peak around 2 hours, and 3-4 hours to clear the system
My main concern is insulin's suppression of growth hormone but the only article I could find was this Insulin suppresses growth hormone secretion by rat pituitary cells.
according to my probably flawed math, 0.7nM of insulin is 4065ng/mL or 4065ug/L aka 89IU/L
So .7nM of insulin inhibited Basal GH secretion by approx 50% (after 8 Days straight of exposure to exogenous insulin in a concentration of 4065ug/ml or 89IU/L)
assuming (again yell at me if my math is wrong) the human body has 5.6 L of blood, that would be roughly 500IU of circulating insulin....
Again I am not claiming this math is right and I want someone to check it for me but after reading that is there any reason to think that the doses we are researching with are anywhere close to enough to inhibit GH secretion? Obviously this is only 1 study but if anyone else has any info please chime in!