Can't edit the post anymore, so let me just add:
From "Use of Dinitrophenol in Nutritional Disorders. A Cirtical Survey of Clinical Results" by Tainter et al.
Average intervention = 300mg a day for about 3 months
Burns fat and carbohydrates while sparing protein. Highly effective at "well tolerated" doses.
Back to the topic at hand here: unlike T3 and Clen, DNP does not affect heart rate or blood pressure negatively, which really is a game changer. I assume a lot of people here are hypertensive.
Side note: Yes, the papers are old and most of this is common knowledge now, but at least we have here what many bodybuilding drugs don't have: Long term human studies with an appreciable number of participants and doses that are common in our circles. Can't really say that about a lot of other drugs.
/e
I have also linked this paper in another thread recently. Interesting read.
2,4 Dinitrophenol as Medicine
From "Use of Dinitrophenol in Nutritional Disorders. A Cirtical Survey of Clinical Results" by Tainter et al.
The total amount of the drug being used is astonishing. For instance, during the past year, the Stanford Clinics have supplied to physicians, or to patients on physicians' prescriptions, over 1,200,000 capsules of dinitrophenol of 0.1 gm. each. Since the usual dailv dose is about 3 such capsules and the average duration of treatment about 3 months, this corresponds to 4,500 patients treated with the drug in a year.
Average intervention = 300mg a day for about 3 months
When the drug is taken in adequate dosage, the increased metabolic activity burns extra fat and carbohydrate and thereby reduces body weight.6 It is very interesting that the protein does not seem to be appreciably affected in the combustion process, as indicated by nitrogen excretion. Accordingly, the tissue framework tends to be conserved.7' 8, 14 In a preliminary report on the loss of body weight in obese individuals,6 it was stated that losses of 2 to 3 pounds a week could be obtained with doses of dinitrophenol which were well tolerated.
Burns fat and carbohydrates while sparing protein. Highly effective at "well tolerated" doses.
Since dinitrophenol can increase the tissue metabolism by a direct action on the cells, without producing the sideactions which accompany metabolic stimulation by thyroid,
One of the most striking features of the metabolic stimulation of dinitrophenol is a lack of significant changes in blood pressure or pulse rate, unless therapeutic doses are exceeded." 6 That is, the metabolism may be increased by as much as 50 per cent without demonstrable changes in circulatory activity. This phenomenon is in striking contrast to the effects of thyroid administration, where circulatory changes are a marked feature of the symptomcomplex.
[..]
Patients who have hypertension can be medicated with dinitrophenol like other patients. As they lose weight, the hypertension is usually improved6and the associated symptoms are ameliorated.
Back to the topic at hand here: unlike T3 and Clen, DNP does not affect heart rate or blood pressure negatively, which really is a game changer. I assume a lot of people here are hypertensive.
Side note: Yes, the papers are old and most of this is common knowledge now, but at least we have here what many bodybuilding drugs don't have: Long term human studies with an appreciable number of participants and doses that are common in our circles. Can't really say that about a lot of other drugs.
/e
I have also linked this paper in another thread recently. Interesting read.
2,4 Dinitrophenol as Medicine