I've tried to ferret out the best routine since 1970, when I first started reviewing studies performed by physiologist and kinesiologist. If you review all the boards and all the training regimens, you get dizzy. 1 set, 4 sets, drop-sets?
We know that taking test alone without doing any resistance work will increase muscle mass. So we can assume that any level of resistance training will increase the amount of mass the testosterone facilitates.
Another fact we can all agree on is that intermittently changing the weight, reps, sets, and exercises - mixing it up a bit - has a beneficial effect.
So the mantras seem to be - "Don't over-train," (you tear down faster than your protein synthesis can rebuild), "Don't get injured," "Don't overtax your CNS," (another outcome that sets you back), and do at least 1 or 2 sets to about 1 rep short of complete failure.
And, all of this will be influenced by your age, diet, rest, and the amount of gear you are taking. If you look at the physiques of bodybuilders over the last 30 years - yes they have gotten bigger; I think that can be attributed to the development of new supplemental techniques more than training.
Arnold looked good 30 years ago. I met him in Hollywood and he was huge. So, have training techniques advanced appreciably since then? We know there are many more approaches - some very complex. The pros are bigger, but 90% of the people on this board are not pros, they just want to make steady progress.
Trying to find the "best" approach is a zero sum game. It is a moving target. We do know that you have to show up, train hard but not over-train, eat right, and take the right stuff.