Custatin C and Hgh

[deathfromabove]

Hello everyone. I just did my 3 month blood test and i have upped my hgh dose to 5iu/day. My current cycle is 500 test 250 EQ 5iu gh 1,5mg reta. All my markers were perfect hct,creatinine,urea,ggt,psa etc. The only marker that was in the top of the high range was Cystatin C which hitted 0.99. I got panicked in the begining thinking EQ may have some effects on my kidneys but my creatine/urea/ACR ratio was perfectly fine. Also my BP is excellent,my fasting insulin is 3.2 and HBa1c is 4.2. In my research i saw that in cases of high igf numbers(mine was 400) Cystatin C can be elevated without indicating renal issues. Considering my other kindey markers are perfect,should i worry? I already changed the EQ with primo because i don't want to take any extra risk. What's your ideas?

 

[nothuman]

Hello everyone. I just did my 3 month blood test and i have upped my hgh dose to 5iu/day. My current cycle is 500 test 250 EQ 5iu gh 1,5mg reta. All my markers were perfect hct,creatinine,urea,ggt,psa etc. The only marker that was in the top of the high range was Cystatin C which hitted 0.99. I got panicked in the begining thinking EQ may have some effects on my kidneys but my creatine/urea/ACR ratio was perfectly fine. Also my BP is excellent,my fasting insulin is 3.2 and HBa1c is 4.2. In my research i saw that in cases of high igf numbers(mine was 400) Cystatin C can be elevated without indicating renal issues. Considering my other kindey markers are perfect,should i worry? I already changed the EQ with primo because i don't want to take any extra risk. What's your ideas?

I was listening to Paul Barnett say a lot of his clients have elevated Cystatin C from EQ. It could be that.

Side note, an A1C of 4.2 is really low. I would explore that a little more if I were you.

 

[deathfromabove]

I was listening to Paul Barnett say a lot of his clients have elevated Cystatin C from EQ. It could be that.

Yeah i know it has some logic but i was running it @ 250mg just for 1 month. Creatinine,urea,electrolytes, and uranalysis all were great thats why I was thinking high igf could be the reason. Thanks for the answer.

 

[deathfromabove]

I was listening to Paul Barnett say a lot of his clients have elevated Cystatin C from EQ. It could be that.

Side note, an A1C of 4.2 is really low. I would explore that a little more if I were you.

As far as a1c I have this since young age. My blood has a super fast reproduction cycle and my insulin sensitivity is nuts. I hit 5iu gh pre bed on a caloric surplus with 600g of carbs and I wake up with 90 BG with just 1,5mg of reta per week.

 

[Stewie]

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[the_unit]

Thyroid function definitely impacts cystatin-c levels, hyperthyroid resulting in higher levels and hypothyroid resulting in lower levels.

 

[deathfromabove]

Thyroid function definitely impacts cystatin-c levels, hyperthyroid resulting in higher levels and hypothyroid resulting in lower levels.

My thyroid function is normal

 

[Shogun]

Get labs done again in 4 weeks now that you removed EQ with primo, it could be the EQ, for some guys EQ does that and other dont get any sides... its person depended same with eq lovering e2 for some and other dont get that affect

 

[deathfromabove]

Get labs done again in 4 weeks now that you removed EQ with primo, it could be the EQ, for some guys EQ does that and other dont get any sides... its person depended same with eq lovering e2 for some and other dont get that affect

Yeah that's the plan mate. Also i did an non sensitive e2 test (immunoassay) and my e2 was 40. I am thinking that the non sensitive test could be fairly wrong but in my location I don't have access to an hplc test.

 

[deathfromabove]

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I read your comment through my email but i dont know why its not showing what you said here. So yes i guess my igf is the contributing factor because all my other kidney markers are perfect. I use Vital Support from TBJP also which has 4g of astragalus plus taurine 3g per day + 4-5 litres of water. I am not heavy just 90 kg. As far as dropping the GH,sorry mate not gonna happen now i am bulking . I dropped EQ,ill wait 5-6 weeks then retest everything and ill report my findings. I'll keep my gh at 5-6 ius per day to see if Cystatin stays high or gets down so i change just 1 thing at a time.

 

[Jose1990]

HGH can elevate Cystatin C and in parallel lower creatinine at the same time in the short term. Like your research suggests. I've seen it.

A lot of training volume and intensity can also raise it.

In your case scenario. I would retest periodically. And then move for an elimination route, eliminating potential compounds.

I'm going to say something controversial. Chinese GH due to fillers in the long term can elevate Cystatin C, while Pharma will lower (as its used in chronic kidney disease).

In any case you can begin thinking about using SGLT2 and possibly finerenone for kidney protection.

 

[deathfromabove]

HGH can elevate Cystatin C and in parallel lower creatinine at the same time in the short term. Like your research suggests. I've seen it.

A lot of training volume and intensity can also raise it.

In your case scenario. I would retest periodically. And then move for an elimination route, eliminating potential compounds.

I'm going to say something controversial. Chinese GH due to fillers in the long term can elevate Cystatin C, while Pharma will lower (as its used in chronic kidney disease).

In any case you can begin thinking about using SGLT2 and possibly finerenone for kidney protection.

I already removed EQ from the equation so the retest in 6 weeks will give me an idea what's happening. As far as intensity i am currently on a HIT Protocol with moderate to low volume and each set is to absolute failure,so that could be a small contributor too. My levels were at the top range not outside of it so i am not thinking to add any medications just for now. As i said BP,FBG,HOMA-IR,Electrolytes, Creatine, Urea,ACR and uranalysis are in a perfect range. I'll update in a month when i retest everything and possible leave 72 hours rest before the blood tests because this time i was only like 36 hours post HIT leg workout