D-aspartic acid

[buck1973]

Going to take d-aspartic acid as part of my pct along with my tore and clomid.
the best info I can find is 3 grams p/d for 2 weeks than a week off?
anyone with some 1st hand?

 

[Massive G]

I do 2 grams twice a day and have stayed on for many weeks - not sure where the 2 weeks came from..

 

[raw33man]

thoughts on this ?

"The distribution of D-Aspartate in the mammalian brain is, for humans, around 20-40nmol/g wet tissue[3] with a higher content of around 320-380nmol/g in the brain of an embryo.[8] One study comparing normal brains against persons with Alzheimer's and found no differences in grey matter, with twice the accumulation in white matter.[9] Interestingly, concentrations of D-Asparate in the hippocampus (dentate gyrus and CA1) are lower in older humans than they are in younger humans which may have roles in memory formation.[10]

In rats, overall concentrations are fairly similar (15-30nmol/g wet tissue) with higher concentrations in the pituitary (120–140nmol/g) in pituicytes,[11][12] pineal gland (650–3000nmol/g) in pinealocytes of the posterior pituitary,[13][14] and to a lesser extent the retina (30-60nmol/g)[15] and in the supraoptic and paraventricular nuclei of the hypothalamus, where the axons of these neuronal clusters end up in the pituitary.[16] Outside of the brain, D-Aspartic Acid builds up in the elongate spermatids of the testicles,[17][18] where the concentrations of D-Aspartate can form up to 60% of all Aspartate and is second only to the pineal gland for highest concentration.[19]

D-Aspartic Acid can be produced endogenously from the amino acid L-Aspartic Acid, via the enzyme Asparate Racemase.[20]

D-Aspartic Acid can get methylated via the enzyme D-Aspartic acid methyl-transferase to become the neurotransmitter NMDA (N-methyl-D-Aspartate), and uses S-Adenosyl Methionine (SAMe) as the primary source of the methyl group.[21] NMDA is an agonist for a subset of glutamate (excitatory) receptors in the brain with a wide range of effects as neuromodulators.[3]

NMDA and D-Aspartate are both metabolized by the enzyme D-amino acid oxidase.[22]"

D-Aspartic Acid - In-Depth Scientific Supplement Information | Examine.com

 

[buck1973]

the last few blood tests I have had
My rdw has been high 16.3 or higher
its always high but never out of range until I started the d aspartic acid
any 1 see I rise in rdw after taken d aspartic acid

 

[soloartist56]

What brands do you guys use ?