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Deca Prolactin Science?

bomb401

New member
Registered
Joined
Jul 15, 2010
Messages
125
Can anyone show me one scientific study showing a 19-Nor like Deca or Tren actually raises Prolactin?

Just curious if this is science or not. lol
 
go watch a vid of a bber shootin milk out of his nips from tren or deca. is that not proof enough lol
 
Many steroids have an affinity for other receptors other than the AR, some actually activate the Estrogen Receptor, some activate the Progesterone Receptor, and some can activate the Prolactin Receptor. Note that these AAS do not activate these receptors as well as the actual correct hormone itself, however they do to a degree. This is known as the hormones "affinity" for said receptor. For example, DHT has 2x the affinity for the AR than testosterone. So while many steroids may not actually raise prolactin in a measurable way, they may activate the receptor to a degree.

While this is a little studied effect, the results (as posted above) speak for themselves. One way to combat this is to lower natural prolactin levels so the overall activation of the PRLR is reduced.

There is also the fact that overly high E2 levels can raise prolactin, AND the fact that the PRLR needs not only prolactin to activate, but also has a co-binding factor which is E2 itself, another words, BOTH E2 and Prolactin are required to activate the PRLR (prolactin receptor).
 
No study exists.

This is one of the biggest myths in our community. That Deca and Tren always increase PRL, they dont. But they can.

Anything that interacts with the estrogen receptor or aromatases, can raise PRL.

Using an AI will help control PRL levels.
 
No study exists.

This is one of the biggest myths in our community. That Deca and Tren always increase PRL, they dont. But they can.

Anything that interacts with the estrogen receptor or aromatases, can raise PRL.

Using an AI will help control PRL levels.

While I agree with you, and there are no studies, I have to admit- without a doubt- that prami helps my nipple soreness while on tren. Bloodwork shows normal prolactin though, I have to assume the affinity theory...
 
I've never had an issue other than gyno, no leaking, but i agree e2 has to be present. But caber after tren/deca does show a difference in labs.
 

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