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Dhea really cause a lot of Estrodiol conversion?

npcout

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Been balanced on doc TRT for 9ish months now. Planning to add my own extras in a bit.

100mg test cyp
1mg adex

Total test: averages 1400
Estrodiol: averages 20

Started 5mg dhea which has worked great for overall sense of well being. Been using 5mg pregnenolone for a few months.

Once I added 5mg of dhea, my nips became swollen and painful. Wasn’t expecting that at all. Nothing else has changed. Is that common?

Adding dhea and pregnenolone has been such a game changer to trt from a non physique side of things.
 
After crashing my E2 with Primo I added 50mg DHEA and 50mg Pregnenolone daily. I got labs in 90 days and it didn’t increase E2 or prolactin at all. No nip sensitivity, no nothing. I dropped it and started taking HCG. But progesterone did increase from .1 to .5 which might have been from taking both? Who knows.
 
Been using DHEA for over 20 years. 50mg/day these days and it does not raise my E2 levels. I have tried Pregnenolone a few times over the years with no noticeable results good or bad.
 
DHEA does increase serum prolactin. But 5mg is such a low dosage. I personally don’t use DHEA unless it’s low on bloodwork. Sticking to HCG and pregnenalone is far more consistent in my experience. You could drop the DHEA and bump the pregnenalone up to 10mg twice daily.
 
DHEA does increase serum prolactin. But 5mg is such a low dosage. I personally don’t use DHEA unless it’s low on bloodwork. Sticking to HCG and pregnenalone is far more consistent in my experience. You could drop the DHEA and bump the pregnenalone up to 10mg twice daily.
Interesting. Maybe it’s a prolactin issue. I bumped my adex dose today, I’ll see if it responds which would be a clue as to e2 vs prolactin. No caber or prami on hand, never crossed my mind for low dose dhea.

I’ve read alot you only need a very low dose of pregnenolone and dhea, and that 5mg is sufficient? Overall, I def respond to them, I’ve noticed quite the difference in overall and mental well being.

I no the legitimate use case for hcg, but how does it effect dhea levels, or act as a suitable replacement. Very curious. Dhea levels were low prior to trt and now bottomed out.

Trying to perfect my trt plan before adding extra goodies.
 
Interesting. Maybe it’s a prolactin issue. I bumped my adex dose today, I’ll see if it responds which would be a clue as to e2 vs prolactin. No caber or prami on hand, never crossed my mind for low dose dhea.

I’ve read alot you only need a very low dose of pregnenolone and dhea, and that 5mg is sufficient? Overall, I def respond to them, I’ve noticed quite the difference in overall and mental well being.

I no the legitimate use case for hcg, but how does it effect dhea levels, or act as a suitable replacement. Very curious. Dhea levels were low prior to trt and now bottomed out.

Trying to perfect my trt plan before adding extra goodies.
In some small capacity HCG can influence DHEA, but it primarily stimulates progesterone and estrogen.

I personally just like sticking to foundational things like TRT and HCG with people unless bloodwork indicates otherwise. Once you start throwing in precursors like DHEA etc things can get thrown off their natural balance.

I’d pull the DHEA and just use pregnenolone for a bit on TRT and give it 6 weeks, then run labs. If you feel it’s a prolactin issue you can check sooner or throw in some P5P. I wouldn’t rush to caber on TRT.
 
In some small capacity HCG can influence DHEA, but it primarily stimulates progesterone and estrogen.

I personally just like sticking to foundational things like TRT and HCG with people unless bloodwork indicates otherwise. Once you start throwing in precursors like DHEA etc things can get thrown off their natural balance.

I’d pull the DHEA and just use pregnenolone for a bit on TRT and give it 6 weeks, then run labs. If you feel it’s a prolactin issue you can check sooner or throw in some P5P. I wouldn’t rush to caber on TRT.
Do you consider HCG essential?
 
Do you consider HCG essential?
Without it you don’t produce LH or sperm for starters. Sure you can live without it by supplementing other things, but why fight natural biology…
 
Raloxifene will reduce some of the prolactin rise from dhea.
 
Raloxifene will reduce some of the prolactin rise from dhea.
Cabergoline is better suited for lowering prolactin. It’s a prolactin inhibitor. Raloxifene excels in blocking estrogen from attaching to receptors in breast tissue to prevent or reverse gyno. Some studies indicate it doesn’t lower prolactin at all.
 
In some small capacity HCG can influence DHEA, but it primarily stimulates progesterone and estrogen.

I personally just like sticking to foundational things like TRT and HCG with people unless bloodwork indicates otherwise. Once you start throwing in precursors like DHEA etc things can get thrown off their natural balance.

I’d pull the DHEA and just use pregnenolone for a bit on TRT and give it 6 weeks, then run labs. If you feel it’s a prolactin issue you can check sooner or throw in some P5P. I wouldn’t rush to caber on TRT.
Good info.

Personally, it wouldn’t even be a consideration to run caber or prami, and prami makes me feel like shit in trt. I don’t want to play polypharmacy with trt, this isn’t a contest prep.

I have used pregnenolone for months, no issues. The side effects started with dhea, and dhea has had noticeable positive effects so I’m hesitant to remove it.

My body type and I am fairly lean, visible 6 pack, has always been sensitive to estrogen. 100mg of cyp without adex flared me up significantly.
 
Cabergoline is better suited for lowering prolactin. It’s a prolactin inhibitor. Raloxifene excels in blocking estrogen from attaching to receptors in breast tissue to prevent or reverse gyno. Some studies indicate it doesn’t lower prolactin at all.

Caber is definitely better. I use that with MENT. no need to go overboard with dhea though. I get nip issues easy and ralox is enough for that on dhea.
 
I’ve read alot you only need a very low dose of pregnenolone and dhea, and that 5mg is sufficient? Overall, I def respond to them, I’ve noticed quite the difference in overall and mental well being.

This is irrelevant to us but I read one manufacturer say androgen free folks could use 5mg of preg and/or dhea to advantage when trying to raise natural test production, whether via "natural" supps or for example enclomiphene. The dosage is too low to cause any potential suppression but could provide "needed" substrate for testosterone production.
 
DHEA does increase serum prolactin. But 5mg is such a low dosage. I personally don’t use DHEA unless it’s low on bloodwork. Sticking to HCG and pregnenalone is far more consistent in my experience. You could drop the DHEA and bump the pregnenalone up to 10mg twice daily.
Would the puffy nipples be a general sign of high e2 if he were just using test only?
 
Would the puffy nipples be a general sign of high e2 if he were just using test only?
I really can’t tell if you’re serious or a troll here with your post, pic and username. But anyone who uses the term “puffy nipples” is usually trolling.

I’m not answering your question. Not because I’m unsure if you’re trolling, but to make this a learning moment- use the search function. I’d bet you could even go on Google and search “puffy nipples professional muscle” and get multiple threads. 😂
 

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