High quality Var, you really only need 30mgs a day. I used to administer it in the hospital setting, it was rarely used but when I did see patients on it, they did get very lean and muscular after a year on even doses as low as 10mgs.
The UGL stuff, yeah you probably need 30-60mgs to get the same effect as many watered down versions. Var can be pretty pricy.
Like anything you get immune to dosages and like someone mentioned, metabolism which is dependent on organ health.
Another thing you can try is to take your orals with Grapefruit Juice. Recall it , in lamens terms can strengthen oral steroids, or medications. Just be careful doing that if you are on any anti psych drugs or strong pain meds bc It can make them so strong, it can be dangerous.
Our results suggest that grapefruit juice may increase bioavailability of orally administered estradiol and progesterone. The response varies markedly between individuals. This observation may be of some importance also for users of OC and HRT.
pubmed.ncbi.nlm.nih.gov