dosage spread out ? t3

[Jaylee]

Okay Guys, I think I've screwed up. I began taking cytomel 2 weeks ago, I with 25mg and then went up to 50mg and now 75mg but I was only taking once per day - it struck me that I was only feeling the effects for a few hours after I took it. Am I supposed to be spreading out throught the day? This is my first time using it and although I see the recommended dosages and cycles, it doesnt tell you anywhere whether to take it once per day or throughout.

Thanks for your help!
Dixie

 

[jawbreakerkid]

based on your name I'm going to go out on a limb here and guess that you're a woman...so based on that assumption I'm going to say 75mcgs of T3 is a very high dose, in my opinion, you shouldn't need more than 25mcgs. Also, I believe the half life of T3 is 24 hours, so once a day doses should be fine.

 

[gooey]

info

The mechanisms by which thyroid hormones exert their physiologic action are not well understood. These hormones enhance oxygen consumption by most tissues of the body and increase the basal metabolic rate and the metabolism of carbohydrates, lipids and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system.

Pharmacokinetics

Since liothyronine sodium (T3) is not firmly bound to serum protein, it is readily available to body tissues. The onset of activity of liothyronine sodium is rapid occurring within a few hours. Maximum pharmacologic response occurs within 2 or 3 days, providing early clinical response. The biological half-life is about 2-½ days.

T3 is almost totally absorbed, 95 percent in 4 hours. The hormones contained in the natural preparations are absorbed in a manner similar to the synthetic hormones.

Liothyronine sodium has a rapid cutoff of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage, should they occur.

The higher affinity of levothyroxine (T4) for both thyroid-binding globulin and thyroid-binding prealbumin as compared to triiodothyronine (T3) partially explains the higher serum levels and longer half-life of the former hormone. Both protein-bound hormones exist in reverse equilibrium with minute amounts of free hormone, the latter accounting for the metabolic activity.

gooey