Coagulation and thrombosis — High doses of fish oil (3 to 15 g/d) increase bleeding time, but this has not been associated with higher rates of clinical bleeding. In a review of 9 randomized trials (n = 2,612), including people taking aspirin or warfarin, no consistent associations were seen between fish oil use or fish oil dose and bleeding risk [21].
In human trials significant effects of fish oil consumption on platelet aggregation are not reliably seen. Consistent changes in fibrinogen, factor VII, or factor VIII are also not identified in controlled trials.
Thus, at least at doses up to 4 g/d (and likely higher), clinically apparent effects of fish oil on bleeding risk are not evident
The above is from our hospital clinial reference MD consults.
In human trials significant effects of fish oil consumption on platelet aggregation are not reliably seen. Consistent changes in fibrinogen, factor VII, or factor VIII are also not identified in controlled trials.
Thus, at least at doses up to 4 g/d (and likely higher), clinically apparent effects of fish oil on bleeding risk are not evident
The above is from our hospital clinial reference MD consults.