For those with Asthma - GHK-cu benefits

[hawkmoon]

I've had asthma for nearly 50 years. While I’m not prone to frequent attacks (I manage allergens and exercise-induced triggers), my lung capacity has been reduced to about 50% due to decades of progressive lung remodeling. Simple tasks, like walking uphill and speaking at the same time, can be difficult. Cardio is challenging, and some nights, I struggle to sleep lying down without significant elevation. Respiratory infections, like Covid or the flu, are particularly risky for me.

I use an inhaled corticosteroid (ICS) and bronchodilator daily, and I keep Ventolin on hand for emergencies, though I rarely need it. I don’t face regular exacerbations because I avoid triggers.

Over the years, I’ve dealt with pain and breathlessness, and while Clenbuterol has helped during tough times, I can’t rely on it long-term. I’ve also used the PowerBreathe device, which I believe has been beneficial.

Recently, I started experimenting with peptides to see if I could find further improvement. While BPC-157 didn’t help—likely because my condition is more about lung remodeling than tissue repair—GHK-Cu has shown significant improvement. Research indicates that GHK-Cu may be beneficial for COPD, helping mitigate lung remodeling and possibly reversing issues like smooth muscle hypertrophy, subepithelial fibrosis, mucus metaplasia, and angiogenesis—all of which contribute to reduced lung capacity.

I introduced Methylene Blue a month after GHK-Cu, and it seems to have provided additional benefits, particularly through its anti-inflammatory effects.

If you're someone with chronic asthma and lung remodeling, I highly recommend giving GHK-Cu a try.

 

[Fleezy]

Isn’t the shot super painful?

 

[Stewie]

It's good that you're getting symptom relief with MB and GHK-Cu.

Although. Have you ever been tested for Alpha-1 antitrypsin deficiency? Generally, symptoms appear early midlife, and later in the age you're at. Unfortunately, AATD can be misdiagnosed as presentations of asthma. A savy clinican, preferably a pulmonologist can dx this with a simple blood test.

 

[Stewie]

Late emend... Savvy.

 

[hawkmoon]

It's good that you're getting symptom relief with MB and GHK-Cu.

Although. Have you ever been tested for Alpha-1 antitrypsin deficiency? Generally, symptoms appear early midlife, and later in the age you're at. Unfortunately, AATD can be misdiagnosed as presentations of asthma. A savy clinican, preferably a pulmonologist can dx this with a simple blood test.

Thank you. I have had bad asthma since I was 8 and been on ICS for 20+ years.
I'll see if I can get it done at my next check-up / blood work appointment. The physicians usually let me browse and select tests in their catalog.

 

[hawkmoon]

Isn’t the shot super painful?

It burns quite a bit. People not prepared will be surprised.
I dilute the 50mg vial of GHK-cu in a 10ml bottle of water. 0.5ml per day, or 2.5mg.

 

[Stewie]

Thank you. I have had bad asthma since I was 8 and been on ICS for 20+ years.
I'll see if I can get it done at my next check-up / blood work appointment. The physicians usually let me browse and select tests in their catalog.

Any first or second degree relatives with COPD- emphysema?

https://www.annallergy.org/article/S1081-1206(13)00719-9/fulltext

Asthma and AATD are 2 distinct conditions yet they can coexist. Although AATD has a variable symptomatology and some patients may be asymptomatic, many can present with symptoms that are similar to those of asthma, such as dyspnea, wheezing, cough, and mucus production, which can cause confusion at diagnosis. A simple genetic test exists for AATD, which is a single-gene disorder, and the American Thoracic Society and European Respiratory Society guidelines recommend the screening of patients with asthma who exhibit chronic airflow obstruction. Patients with AATD are seen by internal medicine, family medicine, allergy, and pulmonary clinicians, yet there is a generalized lack of awareness of testing among all specialties. This leads to a delayed diagnosis for patients with AATD, typically by 8.3 years.

 

[danieltx]

It's great to hear you've found a viable solution. I too had exercise-induced asthma as a child and used a Ventolin inhaler but grew out of it as I hit my teens.

For years everyone's debated what the next big revolution in PEDs would be and I think we're there right now with all the peptides coming out. Most aren't directly performance enhancing but the amount of different peptides discovered to help different things in the body is pretty amazing.

 

[hawkmoon]

Any first or second degree relatives with COPD- emphysema?

https://www.annallergy.org/article/S1081-1206(13)00719-9/fulltext

I'm the only one with respiratory issues.