The very nature of what DNP does, once in your body, would make it obvious to someone educated on the matter that DNP certainly can cause longterm damage
This statement evinces a great deal of ignorance about the research on DNP and its mechanism of action. As 2BIGSTILL said, "Dr.S isnt an expert on DNP and he proved that himself." You proved it earlier with the invented risks (that I called you out on) and you just proved it again asserting "obvious longterm damage." There are dozens of papers on DNP's beneficial effects, including decreasing the mitochondrial membrane potential, attenuating free radical production, reducing oxidative stress, limiting damage in models of injury, increasing lifespan, mimicking exercise and calorie restriction, etc.
Here are a few examples:
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus.
http://www.ncbi.nlm.nih.gov/pubmed/16754295
This landmark paper obviously made an effort to change the widespread misperception that DNP is only dangerous and toxic. It points to protective effects in the brain, possible treatments for neurodegenerative diseases like Parkinson's, and extension of lifespan.
Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity
http://www.ncbi.nlm.nih.gov/pubmed/18505478
In this study from last year they administered a low dose of DNP over the lifespan of mice. They found that treatment with DNP "enhanced tissue respiratory rates, improved serological glucose, triglyceride and insulin levels, decrease of reactive oxygen species levels and tissue DNA and protein oxidation, as well as reduced body weight. Importantly, 2,4-dinitrophenol-treated animals also presented enhanced longevity. Our results demonstrate that mild mitochondrial uncoupling is a highly effective in vivo antioxidant strategy." This study was the third time DNP has been shown to increase in lifespan, following
this study and
this study.
The mitochondrial uncoupler 2,4-dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia.
http://www.ncbi.nlm.nih.gov/pubmed/16045446
This is one of many studies showing that DNP is protective in models where blood flow is interrupted (stroke, heart attack) and then restored. Usually there is a significant oxidative stress upon reperfusion, which DNP attenuates.
Regulation of human male germ cell death by modulators of ATP production.
http://www.ncbi.nlm.nih.gov/pubmed/16403780
This study shows that DNP prevents germ cell apoptosis (death). This is the same thing testosterone does. When apoptosis is accelerated, you can get fertility problems.
Energy requirement for degradation of tumor-associated protein p53.
http://www.ncbi.nlm.nih.gov/pubmed/6325878
p53 is a transcription factor recognized as having anti-cancer effects in cells. DNP has been shown to increase p53 expression. This has been shown both directly in this study and also via AMPK, which DNP is known to activate.
The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord.
http://www.ncbi.nlm.nih.gov/pubmed/15672630
This paper showed that pretreatment with DNP significantly reduced the damage from a bruising injury to the spinal cord. Again, this probably has to do with a reduction in oxidative stress.
Uncouple my heart: the benefits of inefficiency.
http://www.ncbi.nlm.nih.gov/pubmed/19365715
Mild uncoupling of oxidative phosphorylation is one of the mechanisms suggested to be cardioprotective as chemical uncoupling mimics ischemic preconditioning. Uncoupling protein 2 is proposed to be the physiological counterpart of chemical uncouplers and is thought to be a part of the protective machinery of cardiomyocytes... We propose that low concentrations of dietary polyphenols may elicit the same cardioprotective effect as dinitrophenol...
Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction.
http://www.ncbi.nlm.nih.gov/pubmed/19076449
"Our findings suggest that mild mitochondrial uncoupling and caloric restriction exert hormetic effects by stimulating bioenergetics in neurons thereby increasing tolerance of neurons to metabolic stress [e.g. excitotoxicity]."
This are literally dozens of papers like this. Educate yourself. Don't make baseless and foolish statements that "it's obvious to someone educated on the matter that DNP certainly can cause longterm damage." No, it's only obvious to an intellectual coward such as yourself, who invents dangers like "brain, heart, and lung damage" without a modicum of evidence. That's truly pathetic.