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Hi Guys,
Learnt about GW1516 by reading a patent document published online - Unsure if anyone else has read it but below is a paste from the document.
I have put some of the relevant claims in bold - but from what i have read people are using 5mg a day.
1. A method for improving or maintaining muscle tone or mass in a subject having a muscle wasting disease or disorder by administering to the subject an effective amount of a compound comprising an AMP kinase ("AMPK") agonist.
2. The method of claim 1, wherein the AMPK agonist is AICAR.
3. The method of claim 1, further comprising administering an effective amount of a PPARδ agonist, thereby enhancing an exercise effect in the subject.
4. The use method of claim 1, wherein the subject is a mammal.
5. The method of claim 4, wherein the subject is a racing mammal.
6. The method of claim 5, wherein the racing mammal is a horse, a dog, or a human.
7. The method of claim 4, wherein the subject is an adult.
8. The method of claim 1, wherein the subject is an exercise-trained subject.
9. The method of claim 3, wherein the PPARδ agonist is GW1516.
10. The method of claim 3, wherein the PPARδ agonist is administered on the same day(s) on which the AMPK agonist is administered.
11. The method of claim 8, wherein the AMPK agonist is AICAR and the PPARδ agonist is GW1516.
12. The method of claim 3, further comprising having the subject perform aerobic exercise.
13. The method of claim 3, wherein the exercise effect is improved endurance.
14. The method of claim 13, wherein improved endurance comprises improved running distance or improved running time or a combination thereof.
15. The method of claim 1, wherein an effective amount is from about 0.5 mg/kg per day to about 100 mg/kg per day in a single dose or in divided doses.
16. The method of claim 1, wherein the compound is formulated for oral administration, intravenous injection, intramuscular injection, or subcutaneous injection.
Read more: METHODS FOR ENHANCING MUSCLE PERFORMANCE AND TONE - Patent application
Learnt about GW1516 by reading a patent document published online - Unsure if anyone else has read it but below is a paste from the document.
I have put some of the relevant claims in bold - but from what i have read people are using 5mg a day.
1. A method for improving or maintaining muscle tone or mass in a subject having a muscle wasting disease or disorder by administering to the subject an effective amount of a compound comprising an AMP kinase ("AMPK") agonist.
2. The method of claim 1, wherein the AMPK agonist is AICAR.
3. The method of claim 1, further comprising administering an effective amount of a PPARδ agonist, thereby enhancing an exercise effect in the subject.
4. The use method of claim 1, wherein the subject is a mammal.
5. The method of claim 4, wherein the subject is a racing mammal.
6. The method of claim 5, wherein the racing mammal is a horse, a dog, or a human.
7. The method of claim 4, wherein the subject is an adult.
8. The method of claim 1, wherein the subject is an exercise-trained subject.
9. The method of claim 3, wherein the PPARδ agonist is GW1516.
10. The method of claim 3, wherein the PPARδ agonist is administered on the same day(s) on which the AMPK agonist is administered.
11. The method of claim 8, wherein the AMPK agonist is AICAR and the PPARδ agonist is GW1516.
12. The method of claim 3, further comprising having the subject perform aerobic exercise.
13. The method of claim 3, wherein the exercise effect is improved endurance.
14. The method of claim 13, wherein improved endurance comprises improved running distance or improved running time or a combination thereof.
15. The method of claim 1, wherein an effective amount is from about 0.5 mg/kg per day to about 100 mg/kg per day in a single dose or in divided doses.
16. The method of claim 1, wherein the compound is formulated for oral administration, intravenous injection, intramuscular injection, or subcutaneous injection.
Read more: METHODS FOR ENHANCING MUSCLE PERFORMANCE AND TONE - Patent application
