Yes...although peg mgf and igf-1 lr3 MAY be counterproductive (depends on wether u beleive peg mgf actually works somehow for proliferation or if it is a poor mans igf-1....and attaches to igf receptors)
See thats the thing according to DAT, it can only attach to IGF-1 receptors.
He also goes into great depth of how intracellular produced IGF-1 (and their spice variants: incl MGF) act greatly differently inside the cell than they do out. If this theory was correct then injecting both IGF-1 and MGF is almost useless,, i know i know many reading this are thinking thats incorrect, many people grow or "get a pump" from it.
But then again "the pump" experienced can be explained by IGF-1 and MGF alike binding to insulin receptors and of course the IGF-1 receptors which have insulin like effects.
I'm taking IGF-1 right now, 40mcg/day, lowered dose, according to saturation. 20mcg bilateral. But really im not even sure if it's working, according to DAT's theory, and a couple of studies I have read.
Plang whats your opinion?
I mean do you really think MGF causes cell proliferation like intracellular produced MGF (splice variant IGF-1Ec) does?
Do you really think IGF-1 even has growth promoting effects like intracellular produced IGF-1 in the muscle cells does?
They generally say that systemic IGF-1 doesn't have much to do with muscle growth at all.. but then one asks themselves so why are there IGF-1 receptors there then, clearly it's not only intracellular IGF-1 produced, there is systemic IGF-1 produced naturally in the body too, from the liver.
Research is scarce I know.. and thats the main problem. Some have suggested MGF works through a different pathway, and doesn't therefore need the MGF receptor (which are said not to exist).
Others have said MGF is not even extracellularly produced and therefore has no use outside the muscle cell, and will bind to IGF-1 receptors purely because of it's structural similarity to IGF-1 itself, acting only like IGF-1.
Only way one could really argue that IGF-1 or MGF injections are useful, is by experiences of gains and results, in the absence of steroid hormones and other peptides hormones.
Any opinions would be great