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HGH and joint pain

Billy98

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Sep 2, 2025
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I’ve been running HGH for about 4 months now and my joints are killing me particularly my elbows and wrists.. I started on 4ius 2 morning and 2 at night then went to 3 at night now down to 2 at night.. Still having pain.. Is there anything I can do to stop the pain or should I continue to lower my dose..
 
Unfortunately, have experienced this side effect on numerous runs with HGH. Some things that have helped me include: increasing overall hydration/electrolytes (huge factor for me while training in Yucatan), increasing fish oil significantly (3-6g), adding something like bone broth/collagen/cissus quadrangularis, adding diuretics such as dandelion root or HCTZ, using sauna, and trying to back down off or further split up your dosage.

Another area to consider is your training intensity, frequency as a whole. When I run cycles like that my endurance goes absolutely threw the roof and I basically want to train non-stop. Lifting, cardio, swimming, hiking etc My energy and recovery levels can be deceptive and without intentionally pumping the brakes, I feel its easy to over train. One of the first clues would be wear and tear, feeling worn down, or maybe extra pressure on joints.
 
You can drop it till the sides go away and reintroduce it at a lower dose and work your way up. Start at 2iu and work up 1/2 an iu at a time after a couple weeks until satisfied with the dose or sides start then back it down.
 
I’ve been running HGH for about 4 months now and my joints are killing me particularly my elbows and wrists.. I started on 4ius 2 morning and 2 at night then went to 3 at night now down to 2 at night.. Still having pain.. Is there anything I can do to stop the pain or should I continue to lower my dose..
I would start by stoping electrolytes and up your water intake to 1.5 gal to 2 gal a day. most electrolytes will actually pull water and cause more pain, if that doesn't work I would lower the dose and then slowly up it over a couple of weeks at a time.
 
I've had some modest improvement in HGH-related CTS symptoms by supplementing with taurine. It theoretically can help with osmoregulation. I've tried dandelion leaf also, which is supposed to have a diuretic effect, but it didn't help me.
 
plus non-drug or supplement related interventions like maintaining good hydration, focusing on sleep quality, increasing cardio, watching out for diet triggers like [for me] high carb & salt-rich meals
 
I could never get pass the hgh stiffness, I ran it for a year and half and never got over it. Part of me wants to try again as the I was so lean during that time.
 
I’ve been running HGH for about 4 months now and my joints are killing me particularly my elbows and wrists.. I started on 4ius 2 morning and 2 at night then went to 3 at night now down to 2 at night.. Still having pain.. Is there anything I can do to stop the pain or should I continue to lower my dose..
15mg daily of meloxican, I dropped hgh can't say I do t regret it, don't need it.
 
Joint pain on HGH is often misunderstood. Most beginners think it’s 'dryness,' but it’s usually the opposite: intra-articular water retention and the rapid growth of connective tissue. HGH causes your body to hold sodium and water inside the joints, which increases pressure on the nerves.

Also, if your dose is high (4iu+), your tendons might be thickening faster than your nerves can adapt, causing that 'tight' feeling. My advice: Drop the dose to 1.5-2iu for a couple of weeks to let your body desensitize, and make sure your potassium/sodium balance is dialed in. Pushing through carpal tunnel or joint edema on GH isn't a badge of honor; it's a sign your titration was too aggressive.
 

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