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High ammonia levels

NH, I can’t believe you’re still going through this. I truly feel for ya. Out of curiosity, why the l-glutamine?
 
Well I have been using 10g glutamine for the last two months ever since I got the high ammonia level so now I will have to do more research on it to see if I should continue. Every other link I read says to take it. It's a shame the study you sent if so difficult to understand. I hate when the people who write these papers use such big words and don't convey the message properly.

I started Lysine two days ago so I will have to look into that too.

My blood pressure is very low so I have to be careful as well when it comes to citrulline and arginine. 105/57 is how low it's been lately. Thyroid and cortisol problems are also destroying my quality of life in addition to the ammonia.

What supps are you taking that lower blood pressure? Any medications? Are you still using frequent tadalafil? So many of the main supps many use can lower bp so I assume you are on quite a few. Perhaps drop a few of them and add the citrulline in.
 
NH, I can’t believe you’re still going through this. I truly feel for ya. Out of curiosity, why the l-glutamine?

Thanks man. It's been a brutal 2 1/2 years. It got to the point last winter that I finally gave up on trying to live on despite this so I've been in full on hibernation mode until I can live a normal life again.
 
What supps are you taking that lower blood pressure? Any medications? Are you still using frequent tadalafil? So many of the main supps many use can lower bp so I assume you are on quite a few. Perhaps drop a few of them and add the citrulline in.

I don't usually take cialis anymore. No headaches. No BP meds. I just eat such a nutritious diet and do take supps that could be lowering it. The garlic cloves I eat too. I do not believe any symptoms are related to my BP, because I feel exactly the same even when it's 125/70
 
I don't usually take cialis anymore. No headaches. No BP meds. I just eat such a nutritious diet and do take supps that could be lowering it. The garlic cloves I eat too. I do not believe any symptoms are related to my BP, because I feel exactly the same even when it's 125/70

I didn't think that either. I just meant if you are taking anything that can lower blood pressure and it's at that level if you throw in a high dose of l-citrulline it could lower it too much and you have some issues (dizziness etc). Basically just the same thing you stated and you have to be careful adding in nitric oxide expanders because your bp is already on the low side. As you know l-citrulline is very effective at lowering ammonia so I would recommend it so you will have to drop something. I thought you still took cialis which could have been a easy option.

It's up to you and I don't know what you take now but so many things can lower bp. I know you use high dosed fish oil so that is one, garlic (gloves) is 2. I assume you use magnesium so that is 3. I think you use ubiquinol so that is 4. You definitely use curcumin so that is 5. You definitely use vitamin d so that is 6. I am not stating they are all lowering your bp (far from it) but the potential is there as they are all known for it. So the combination of everything may have your numbers a bit lower than they would be without using them. So I guess you have to decide which ones are most important to you right now and maybe drop a few and add in citrulline as ammonia is your main concern right now. It's just a shame some of the best overall supplements for general heart health do also have the potential to lower blood pressure.

It's up to you and you may be fine just adding citrulline in and not dropping anything but that's exactly why I suggested starting with a lower daily dose and see how you are then possibly move up in dose if you are fine and obviously get your ammonia retested to see if there is a difference. What did you lower your protein to?
 
Serum ammonia levels fluctuate during the day .
I think that can be your secondary concern.
My suggestion is that you look at your Thyroid first.
A disruption in your calcium pathways will wreck havoc both mental and nenuber mauromuscularly.
Many times it will be ever so slight, whether hypo/hyper i your numbers will fall in range.
We have been fed the thought we ALL have a slowing metabolism....
The reality is that our lifestyles, diet,and supplementation is all geared to "REV our metabolism".
A small shift in that axis can throw you off.
I would suspect slight hyperactivity of the thyroid.
The cause is the "hidden IODINE".
They are just IMO.
 
Serum ammonia levels fluctuate during the day .
I think that can be your secondary concern.
My suggestion is that you look at your Thyroid first.
A disruption in your calcium pathways will wreck havoc both mental and nenuber mauromuscularly.
Many times it will be ever so slight, whether hypo/hyper i your numbers will fall in range.
We have been fed the thought we ALL have a slowing metabolism....
The reality is that our lifestyles, diet,and supplementation is all geared to "REV our metabolism".
A small shift in that axis can throw you off.
I would suspect slight hyperactivity of the thyroid.
The cause is the "hidden IODINE".
They are just IMO.

I have had confirmed lower Free T3 for quite a long time now (with normal TSH and no antibodies). I believe the thyroid medication had failed me because I’ve used too high of a dose too quickly and it completely suppressed my TSH, making myself completely dependent on medication when I needed to work my way into it. I will be starting 30mg Armour before bed again tonight now that I have my blood drawn and simply stay at that dose.
 
Obviously it's all guess work but hopefully optimizing your thyroid will make a big difference. Sometimes it only takes something fairly small to knock something off but the side effects can be significant.

Have you ever thought about just have a massive clear out? Meaning drop all (or most) supplements and just see how you are in a few months. It's a lot for the body to process throughout the day. I know for me personally it makes a big difference as do AAS. I know you have only used small doses for a long time but it can all be a factor. Many things increase my fatigue. 10mg MK-677 or 2iu HGH and I can barely function. I am not for 1 second stating that is what is causing your issues as I doubt you even use any of them but just highlighting even 1 drug or 1 supp could be throwing you off. Worst case scenario you stop them for 2 months it makes no difference so you just go back on them. I doubt your health blood markers will change by dropping everything (most things) especially if you just stay on a low dose of trt the entire time.
 
Holy false alarm. My ammonia was tested yesterday and it was only 21! Looks like my symptoms have nothing to do with this

^^^VERY GLAD to read this brother

BUT F*CK lol ..i was just finishing a 3 mile long PM to you regarding "urea cycle dysfunction & ammonia overload"

ya ..1 thing about ammonia over load is you will stink ..your pee, your sweat will stink etc
(..which, just as stated in the study BIO posted #15, can happen with normal liver labs


..happy that at least the list shortens for you


.
 
^^^VERY GLAD to read this brother

BUT F*CK lol ..i was just finishing a 3 mile long PM to you regarding "urea cycle dysfunction & ammonia overload"

ya ..1 thing about ammonia over load is you will stink ..your pee, your sweat will stink etc
(..which, just as stated in the study BIO posted #15, can happen with normal liver labs


..happy that at least the list shortens for you


.

Ah man, well I appreciate the effort of typing it up! you still could have hit send anyway lol
 
NH, I can't remember the exact terminology, but IIRC, you had problems with your aortic valve basically splitting open (ugh...correct and update that for me...)? Is there anyway you could still be undergoing any kind of stenosis of that valve, or something similar?

If so, i'm sure that could be a factor (not saying that's what's going on), as it will be similar to what a lot of people feel who need a TAVR or similar surgery from stenosis.

Just throwing that out to get your thoughts?
 
Obviously it's all guess work but hopefully optimizing your thyroid will make a big difference. Sometimes it only takes something fairly small to knock something off but the side effects can be significant.

Have you ever thought about just have a massive clear out? Meaning drop all (or most) supplements and just see how you are in a few months. It's a lot for the body to process throughout the day. I know for me personally it makes a big difference as do AAS. I know you have only used small doses for a long time but it can all be a factor. Many things increase my fatigue. 10mg MK-677 or 2iu HGH and I can barely function. I am not for 1 second stating that is what is causing your issues as I doubt you even use any of them but just highlighting even 1 drug or 1 supp could be throwing you off. Worst case scenario you stop them for 2 months it makes no difference so you just go back on them. I doubt your health blood markers will change by dropping everything (most things) especially if you just stay on a low dose of trt the entire time.

I stopped all supplements for two weeks once roughly a year ago and definitely felt worse. I couldn’t wait to start back up.

My thyroid is a huge problem. I felt horrific this morning and took my temp and it was 95.7F (35.4C). I’ll have fresh results to confirm that next week. I believe it’s as simple as this but we will see how I feel once I finally resolve this thyroid problem that has plagued me so long
 
NH, I can't remember the exact terminology, but IIRC, you had problems with your aortic valve basically splitting open (ugh...correct and update that for me...)? Is there anyway you could still be undergoing any kind of stenosis of that valve, or something similar?

If so, i'm sure that could be a factor (not saying that's what's going on), as it will be similar to what a lot of people feel who need a TAVR or similar surgery from stenosis.

Just throwing that out to get your thoughts?

I have a leaky aortic valve (regurgitation) that is classified as moderate but every cardiologist I’ve seen says it’s not nearly bad enough to cause symptoms like this. I’m not at the point where TAVR is an option yet, but I wouldn’t hesitate to get it if got to that point.
 
Whats your blood pressure over a period?
 
Whats your blood pressure over a period?

With my two home BP monitors, it's average 106/60. At any doctor's office, it's like 140/80. Go figure.
 
Do you drink a lot of alcohol ? or at least alcohol daily ?

Have not had one drop since new years eve while I've tried to heal myself. I can't wait to have a glass of wine or a beer again when I'm healthy.
 

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