It's absolutely possible that generic GH is being diverted from a sophisticated pharm company from overseas that provides real 22 kDa rhGH. It's also possible, and I believe more probable, that the predominant generic market are peptides similar to the 3D structure of 22 kDa rhGH but slightly off. Plenty, plenty of peptide structures could activate the hGH receptor without having the torsional force at the GHR that 22 kDa does. For example, some of our endogenous hGH is the 20 kDa isoform, and it does not phosphorylate the downstream targets as potently as 22 kDa. Given the lack of regulation in the black market, it's extremely probable that we're dealing with GH analogues. Which still work to a greater or lesser extent dependent on the structure.
When it comes down to practical effects particularly the activation of liver-released IGF-I, there are myriad molecules aside from "the one true molecule" that for our purposes work just as well. They just won't work as well as 22 kDa for GH-specific effects.
I get what you’re saying, but again, you’re using fancy words instead of addressing how you have evidence to think it’s a GH analogue instead of true HGH?? Besides that it’s cheaper so it has to be some kind of GH mimic...
All the tests and comparisons come back the same...
Members on here with decades of experience report the exact same effects from Pharma and some well known, reputable and tested generics...
Guys like Alex Kikel as I said above, talk about generics and GH in general and the cascades and effects etc..
You’re saying it’s probably some type of mimic drug close to GH..... Yet it gives all the same effects and cascades as real GH?
Well if it quacks like a duck Bro, then it probably is a duck and you’re just trying to nit pick and find a reason (for whatever reason) to go against generics...
As I said in my post; there are countries you can get Nordis, Humatrope, Geno’s etc for literally the price of TP’s Grey Tops... Are those analogues too?? No...
The US is the only place where 100iu of Pharma GH costs $1,000... (give or take, but just for conversation sake)..
Also, that I’m aware of, there is no patent on HGH (something which I believe controls the high prices of certain medications), so other companies are allowed to make it legally without issue in generic form.. There are countries that use generic GH in their pharmacies as I said before... So I think it’s more than likely that good generic GH is being produced in real facilities and just being back doored like everything in China is...
If you don’t like them or can’t find one you trust, then cool bro. If you make a great living and would rather spend 10x on Pharma because you feel like it, then more power to you bro....
But that’s like saying my Sun Pharma generic Test Cyp that I’m prescribed is a mimic because it’s cheap (I get it for free from insurance) or my Generic Cialis made in India (which I’m also prescribed here in the US) has to be a mimic because the Eli Lilly Cialis costs $300+ for 30 pills and mine costs $14 for 30 so how is that possible?! It must be fake. No bro. Making these drugs, GH included isn’t as complicated as they made it seem 20 years ago when 100iu of generics used to cost $500 and I remember people used to say you can’t even squirt the Bac water on it because you’d ruin the whole thing and that it can only be in the fridge reconstituted for a couple days MAX... Lmao... We know now that is not the case..
I think you’re still living in 1994 with some of these things man lol...
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