I'm slowly adjusting.. Was on 600 mgs test.. Was using .5 a day after using 1 mgs a day for 4 days my joints took a beating so,went to .5 ., I'm very estro sensitive.. But even that brief journey to 1 mg took a week or more to get my joints right.. Then I noticed very dark urine.. A side effect of arimidex.. I then dropped to .5 eod.. I am staying there until I get blood work at end of month., but I can tell Ya from just my personal experience this shit is powerful.. I'm taking pharm grade and it's much more effective than any liquid research I've taken .. So if your arimidex is dosed right it doesn't take much at all to get e2 in line.. I notice at .5 Eod i have good sex drive.. I get erections just fine.. At .5 Ed I notice all is fine for a bit then dark urine and erections get weak.. Again without blood work it's just a guessing game..m