It improved mine at 200mg cyp a week. I am on Dr prescribed Trt and my total cholesterol dropped from 220 to 183, lowered my triglycerides into the normal range, raised my HDl 8 points, and lowered my LDL.
I also read that some people have High cholesterol because they are not converting Cholesterol to pregnenolone so supplementing with pregnenolone in theory lowers cholesterol in those with that problem.