IM or SQ. I personally don't get any problems with injecting it SQ, so that's the way I do it.
Most people use the dosage on the bottle. I say that you can get away with that EOD. But it's a natural product, so you can take more with no sides.
When I'm a fat bastard in the winter, I can do sub Q no problem. But I find that as I lean out, I get problems with the inject site swelling a bit and getting a bit soar. Probably because the liquid has less room to move. So if you are like me and put on that winter coat, sub Q will probably be ok. Otherwise go IM.
Well, it doesn't. That's why I say that doing it every day is best, but you can get away with EOD. Basically the reason why I do EOD is because I am sick of so many shots that I have to do, so I try to minimise them. EOD with Syntheselen is enough to get by on.