- Joined
- Sep 4, 2015
- Messages
- 230
Mike Arnold just started a large thread about exactly that. You may want to look into that?
CG
Ya I did this is why I'm asking for members experiences with log or humalin r. Thx man
Mike Arnold just started a large thread about exactly that. You may want to look into that?
CG
The way I read this it would be a negative. It interferes with androgen upregulation which is good if we are taking about cancer cells bad if we are talking about muscle cells. One has to believe that if it cause down regulation in cancer cells it would do the same in muscle cells.The study I referred to didn't say it 'benefitted' them, I didn't mean to imply it benefitted them, however, it did 'benefit' them from a health standpoint in interfering with androgen influenced up regulation in prostate cancer.
Metformin Inhibits Androgen-Induced IGF-IR Up-Regulation in Prostate Cancer Cells by Disrupting Membrane-Initiated Androgen Signaling
The way I read this it would be a negative. It interferes with androgen upregulation which is good if we are taking about cancer cells bad if we are talking about muscle cells. One has to believe that if it cause down regulation in cancer cells it would do the same in muscle cells.
I believe there is better options than met. Out there but people will have their own opinions. Personally I think the majority of the ways in which it works are simply not conducive to bodybuilding.
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Not going to argue the berberine fact but its a safe assumption to make that if it has an effect on them in one tissue chances are it has it on other tissues. Would you not agree?At this point there's no literature stating metformin acts on nontumorigenesis AR. Obviously it does on PC oncogenesis. Tissue specific doesn't necessarily mean systematic.
Incidentally, berberine acts very similarly. Although that fell on deaf ears.
Not going to argue the berberine fact but its a safe assumption to make that if it has an effect on them in one tissue chances are it has it on other tissues. Would you not agree?
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I agree with you on just about everything in this post. Except for emailing the researchers. He can you do a human study on ar in muscles on people on steroids and really excessive amounts of them at that. Oh throw GH and peptides in there if you don't mind. Come on bro let's be real. People don't mind their cancer cells being biopsied but not many are lining up to have hunk of their muscle cut out in the name of research especially bodybuilders. In cases like they we have to use rational logic. If you don't want to agree that's fine but you cannot disagree either which is what you have done until this point.That's my point, we don't know for sure.
The best bet we as a community could do to end this debate and put it to rest, is to email the researchers involved. Believe it or not, some researchers enjoy this. My genetics professor was a researcher at Loyola University. He's mentioned durning a few of his lectures on individuals that have emailed questions regarding previous research that's been published, that's highlighted the portion of his lectures.
So to answer your question, no I can't agree with you or anyone else at this time, until the proper authority states otherwise.
I agree with you on just about everything in this post. Except for emailing the researchers. He can you do a human study on ar in muscles on people on steroids and really excessive amounts of them at that. Oh throw GH and peptides in there if you don't mind. Come on bro let's be real. People don't mind their cancer cells being biopsied but not many are lining up to have hunk of their muscle cut out in the name of research especially bodybuilders. In cases like they we have to use rational logic. If you don't want to agree that's fine but you cannot disagree either which is what you have done until this point.
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If one is using novolin r preworkout would it be pointless to do cardio right after weights ? Let's say u take 10 iu r 30 min before weights and have 50 g carbs.. Then another 25-50 intra workout and then do cardio after weights... Then post workout meal..would the cardio be pointless as the insulin and carbs are still in system ????