Buy Needles And Syringes With No Prescription
M4B Store Banner
intex
Riptropin Store banner
Generation X Bodybuilding Forum
Buy Needles And Syringes With No Prescription
Buy Needles And Syringes With No Prescription
Mysupps Store Banner
IP Gear Store Banner
PM-Ace-Labs
Ganabol Store Banner
Spend $100 and get bonus needles free at sterile syringes
Professional Muscle Store open now
sunrise2
PHARMAHGH1
kinglab
ganabol2
Professional Muscle Store open now
over 5000 supplements on sale at professional muscle store
azteca
granabolic1
napsgear-210x65
advertise1
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
ashp210
UGFREAK-banner-PM
esquel
YMSGIF210x65-Banner
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store

Interesting article on TB-500 and cartilage

CYCLEON

New member
Newbies
Joined
Sep 21, 2010
Messages
24
Thought I would look into TB-500 a little as I have a partial ACL tear and have considered prolotherapy and other possibilities to strengthen it back to where I can feel confident in my heavy lifts again. This is from 2002 but gives me hope that thymosin could be indeed helpful in repairing soft cartilage and strengthening what I have.


Biochem Soc Trans. 2002 Nov;30(Pt 6):879-82. Related Articles, Links

The effect of thymosin beta4 on articular cartilage chondrocyte matrix
metalloproteinase expression.


Blain EJ, Mason DJ, Duance VC.

Connective Tissue Biology Laboratories, School of Biosciences, Cardiff
University, Museum Avenue, Wales, UK. [email protected]

Mechanical loading is paramount in regulating both the anabolic and
catabolic activities of articular cartilage chondrocytes, essential for the
matrix to retain its functional integrity. We have identified thymosin
beta(4) as a putative mechanically regulated gene that may mediate
load-enhanced synthesis and activation of matrix metalloproteinases (MMPs) 2
and 9 in articular cartilage. The objective of this study was to confirm the
mechanical regulation of thymosin beta(4) and determine its effect on
cartilage chondrocyte MMP production. Thymosin beta(4) mRNA expression,
analysed by quantitative PCR, revealed a significant 20-fold increase in
cartilage loaded for 10 min which was still evident after 30 min of loading.
Treatment of primary chondrocytes with 2 and 4 micro x ml(-1) thymosin
beta(4) peptide for 4 h significantly increased pro-MMP 9 expression and
activation. We postulate a functional role for load-induced thymosin beta(4)
in modulating the cytoskeletal organization of articular cartilage
chondrocytes to affect MMP expression.

PMID: 12440937 [PubMed - indexed for MEDLINE]
 

Staff online

  • K1
    Blue-Eyed Devil

Forum statistics

Total page views
558,058,924
Threads
135,758
Messages
2,768,695
Members
160,343
Latest member
12cc
NapsGear
HGH Power Store email banner
your-raws
Prowrist straps store banner
infinity
FLASHING-BOTTOM-BANNER-210x131
raws
Savage Labs Store email
Syntherol Site Enhancing Oil Synthol
aqpharma
yourmuscleshop210x131
hulabs
ezgif-com-resize-2-1
MA Research Chem store banner
MA Supps Store Banner
volartek
Keytech banner
musclechem
Godbullraw-bottom-banner
Injection Instructions for beginners
Knight Labs store email banner
3
ashp131
YMS-210x131-V02
Back
Top