- Joined
- Apr 9, 2021
- Messages
- 1,701
Sure if your blood pressure is high, telmisartan makes sense. It has some ancillary benefits. Just know that It also may cause:I follow Victor Black on Instagram (John J as well) and the amount of usable, free content Victor puts out is insane! ALL (100%) of it backed up by published clinical studies/evidence. You're absolutely allowed...and even encouraged...to refute anything he says. His only rule is you need to produce clinical evidence to back up your statement or claims...no bro science! He preaches from a podium of "safer use models" and "let's plan out the next 20 years...not just the next 20 weeks." He totally gets that guys will use a gram of AAS, add in insulin, and throw in 4-6iu of gh. He doesn't crucify you for that....just understand that there's consequences for that over the long term. He's trying to get guys to understand that if you live this lifestyle there's a safer, longer-term way to do it and still reach your goals while being healthier. He also believes everyone is a genetically-unique individual and responds differently to the introduction of various compounds and dosages. By the way, here are the benefits of telmisartan as reported in clinical studies at dosages as low as 20mg/day:
It doesn't take much over TRT-level doses and adding in a secondary compound to start negatively affecting our health markers. Again, keeping in mind that we're all genetically unique individuals.
- Modulates BP
- Lowers hematocrit
- Modulates water retention
- Mitigates cardiac remodeling/LVH
- Mitigates kidney stress
- Improves insulin resistance
- Improves lipid profile - increases HDL
- Possible myostatin inhibitor
As a 52-year old guy who's been doing this a long time...and who still wants to be doing it in 20 years because I enjoy it...I'm all about safer-use models and adding in stuff like telmisartan if it can make a positive difference. Stay safe out there guys!!
1a. potassium dysregulation, e.g. hyperkalemia (increased potassium retention despite its direct action), and 1b. electrolyte imbalance
2. ALT/AST elevation that can complicate oral androgen use
3. severe hypotension for those with salt/electrolyte depletion or prolonged diuretic use
4a. kidney/renal (GFR, eGFR) dysfunction (yes, even though it's used as a therapeutic for diabetic nephropathy - kidney function should be monitored with use of this drug), and with those that have decreased cardiac function (e.g., heart failure) can cause 4b. acute kidney failure
Some drug-drug interactions:
Unfavorable: decreased tamoxifen metabolism; diuretics (this should be obvious)
Unclear: decreased raloxifene excretion resulting in a higher serum level
Favorable (I'd add to the list of benefits): decreased excretion rate of testosterone resulting in a higher serum level