DAT says stick to 100mcg of each and dose them more frequently to get the best results. I have my dose down to 200mcg on ghrp-2 and it hits pretty good, nothing like 1,000mcg, but DAT says that head rush isn't an indication of how much hgh is being released. He is the expert. He says go by how well you sleep at night. I sleep very well after taking 200mcg ghrp--2, 150mcg mod grf, 1iu hgh, 50mcg des, and 50mcg Lr3...yes, I take all these.