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Hey bro's, I thought I would share this info.
My wife has kidney issues. When I met her they only function at around 50%. There are those who say you can repair kidneys but I think that’s BS. I made her this list a few years ago and she bought her most of these supplements. Her Kidneys are now at 75%. So I’m sure they will help you boost your kidneys.
(CoQ10) can improve kidney function and reduce the need for dialysis.
Coenzyme Q10 Beneficial for People with Kidney Failure By Alan R. Gaby, MD Healthnotes Newswire (July 17, 2003)Supplementing with coenzyme Q10 (CoQ10) can improve kidney function and reduce the need for dialysis in people with severe, chronic kidney (renal) failure, according to a study in the Journal of Nutritional and Environmental Medicine (2003;13:13–22). If this study is confirmed, CoQ10 therapy will represent a major breakthrough in the treatment of a disorder that is both debilitating and a significant drain on our healthcare resources.
In severe, chronic renal failure, the kidneys lose their capacity to excrete waste products of metabolism and other toxins. Consequently, these substances accumulate in the body, leading to various problems such as fatigue, loss of appetite, anemia, disorders of the nervous system, heart disease, and ultimately death. Common causes of chronic renal failure include diabetes, hardening of the arteries (atherosclerosis), and high blood pressure.
People with advanced renal failure are usually treated three or more times per week by a procedure called dialysis, in which a machine is used to filter the toxins from the blood. While dialysis can prolong life in people with advanced renal failure, it is associated with a number of adverse effects, including low blood pressure, infection, and worsening heart disease. In addition, dialysis is expensive, costing more than $50,000 per year at some centers. Any treatment that has the potential to improve kidney function and reduce the need for dialysis would be a significant advance.
In the new study, 97 people (average age, 48 years) with chronic renal failure were randomly assigned to receive a placebo or 60 mg of CoQ10 by mouth three times per day for 12 weeks. Among the 45 participants who were already receiving dialysis, supplementation with CoQ10 resulted in an improvement in various measures of kidney function, including serum creatinine (29% improvement) and blood urea nitrogen (9% improvement). In contrast, kidney function tended to worsen in the placebo group, and the differences between CoQ10 and placebo were statistically significant. CoQ10 also produced significant improvements relative to placebo among the participants who were not receiving dialysis. By the end of the study, the number of people requiring dialysis had decreased from 21 to 12 in the CoQ10 group, but remained unchanged at 24 in the placebo group.
These results suggest that treatment with CoQ10 improves kidney function and reduces the need for dialysis in people with chronic renal failure. Because CoQ10 has the potential to revolutionize the treatment of chronic renal failure, a large-scale, long-term study should be initiated as soon as possible.
Alan R. Gaby, MD, an expert in nutritional therapies, testified to the White House Commission on CAM upon request in December 2001. Dr. Gaby served as a member of the Ad-Hoc Advisory Panel of the National Institutes of Health Office of Alternative Medicine. He is the author of Preventing and Reversing Osteoporosis (Prima, 1994), and co-author of The Natural Pharmacy, 2nd Edition (Healthnotes, Prima, 1999),
CoQ10 (Coenzyme Q10) and Renal Failure Chronic renal failure (CRF) is the progressive loss of kidney function.
Chronic Renal Insufficiency (CRI) is the early stage, when the kidneys no longer function properly but do not yet require dialysis.
CoQ10 was studied in a small pilot study involving 21 patients with chronic renal failure. Researchers administered CoQ10 to 11 of the subjects while 10 received a placebo capsule. To be included in the study patients had to have a creatinine level of 5 mg/dl or above. After 4 weeks, the subjects receiving CoQ10 had significant decreases in serum creatinine and urea while creatinine clearance significantly increased. At the end of the 4 week study the number of patients on dialysis was significantly less in the CoQ10 group. 36.2% of the patients in the CoQ10 group were on dialysis at the end of the study while 90.0% of the placebo group were on dialysis at the end of the study.
An increase in blood antioxidant levels and a significant decrease in indicators of oxidative stress were noted by the study group. (J Nutr Environ Med, 2000; 10: 281-288)
"Randomized, Double-Blind Placebo-Controlled Trial of Coenzyme Q10 in Chronic Renal Failure: Discovery of a New Role," Singh RB, Khanna HK, Niaz MA, J Nutr Environ Med, 2000;10:281-288.36843
Yes, baking soda really did help some patients with chronic kidney disease and metabolic acidosis. In the Royal London Hospital study, reported in the Journal of the American Society of Nephrology, participants took a small daily dose of sodium bicarbonate (baking soda) in tablet form. sodium bicarb tablets 1300mg twice a day
Herbs
Ganoderma Lucidum and Cordyceps Sinensis
Coq10 for reversing kidney disease - The Studies
One study looked at 15 patients who were "uremic' - meaning they at the end stage of renal failure where at least two thirds of the kidney cells (nephrons) have been destroyed. And compared their coq10 levels with the control group of 10, as well as the coq10 levels of 48 patients on chronic hempdialysis, and found the coq10 levels were significantly lower in the group on hemodialysis and the uremic patients compared to the control group. This study did not involve any supplementation, merely looked at the body's coq10 levels.
One study which did measure the effect of supplementation with coq10 in patients with chronic renal failure found that those in this study who were receiving the coq10 and were on dialysis, had improved kidney function. At the end of the study, the number of people needing dialysis that had been using coq10 was reduced - from 21 to 12, which is a huge improvement. Especially considering there was no reduction in the number needing dialysis in the group who received the placebo. So with regards coq10 for reversing kidney disease, the question is still out, after all we don't know from this one study what mechanisms of action the coq10 helped. Kidney disease is a result of the death of kidney cells, and there was no mention of coq10 regenerating those cells. But it is certainly very promising in managing and improving the health of those with kidney disease.
References: C Porth, Pathophysiology: Concepts of Altered Health States 4th Ed. (J.BLippincott Company, 1994)
Renal Shield
Investigations have shown that cordyceps sinensis could enhance kidney functions, shielding it from impairment caused by nephrotoxic chemicals. Research conveyed that the condition of patients with chronic renal failure enhanced in as little as 30 days. In fact, a distinguished regeneration of renal tubular cells was obtained in subjects provided with cordyceps sinensis. A scientific analysis published in Nephrology Dialysis Transplantation reports that three grams of cordyceps sinensis per day is adequate to shield the kidney against cyclosporine-instigated nephrotoxicity. The research, implemented on 69 kidney transplant patients, proffered cordyceps sinensis as a catalyst in the diminution of cyclosporine instigated renal toxicity, thus shielding the kidney to nephritis.
Cordyceps (Cordyceps sinensis), a fungus found growing in caterpillar larvae of certain moths, has long been valued as a kidney tonic in China (Zhu, Halpern, & Jones, 1998). One study in 61 patients with lupus nephritis showed that a combination of 2 g to 4 g of cordyceps powder together with 0.6 grams of artemisinin from the plant Artemisia annua for 3 years improved kidney function as measured by creatinine clearance (Lu, 2002). Another study found that cordyceps lessened the nephrotoxicity of cyclosporine in kidney transplant patients (Xu, Huang, Jiang, Xu, & Mi, 1995). An anti-oxidant protective mechanism was postulated for this protective effect. The Japanese traditional remedy Sairei-to, a 12 herb mixture, has shown in human and animal studies to protect the kidney in gentamicin renal toxicity, IgA nephropathy, and lupus nephritis (Ohno et al., 1993). Another study in rats showed that extracts from the root of the plant Salvia miltiorriza (Danshen) along with fructose 1-6 diphosphate prevented the decline of renal cortical Na-K-ATPase activity induced by ischemia and gentamicin (Lu & Li, 1989). Further, extracts of the plant Herniaria hirsute inhibit calcium oxalate crystal aggregation and thus could be useful in preventing kidney stone formation (Atmani & Khan, 2000). In summary, there seems to be many potentially protective medicinal plants and supplements that may protect the kidney perhaps via acting primarily as anti-oxidants (see Table 2 ).
In terms of creatinine levels: yes, there is an easy way to get your creatinine levels down, don't work out and lie in bed for as long as you can. Once your muscle mass is lost, your creatinine will also go down. The point I'm trying to make is that creatinine levels themselves are only indirectly assoiated with kidney function. Depending on how much muscle you have, you are constantly producing creatinine and spilling it in to your blood and then your urine
Improving Creatinine Levels
Creatinine - Serum AdsLowering Creatinine LevelsDiabetic Blood Sugar LevelTriglycerides LevelsDiabetes Glucose LevelsHigh Creatinine
Creatinine is a waste product that forms when creatine is broken down. The kidneys are responsible for eliminating this waste product from the body, so blood creatinine levels are an important indicator of kidney function. If blood creatinine levels are too high, it can indicate a decline in kidney function. There are some steps that can improve creatinine levels and reduce the workload on the kidneys.
Reduce Protein Intake
Creatine is a substance that is found in high-protein animal products such as red meat and poultry. When creatine is broken down for energy, creatinine is produced. One way to improve blood creatinine levels is to reduce the amount of protein that is eaten in the diet. When consumption of these high-protein foods declines, there is less creatine available to break down into creatinine. Eating less protein can also reduce the amount of work the kidneys have to do to filter the blood and remove waste products from the body.
Increase Fluid Intake
While high creatinine levels can indicate a serious medical condition, dehydration can also cause an increase in serum creatinine. Increasing fluid intake can help avoid dehydration and eliminate the possibility of elevating creatinine levels. The Institute of Medicine recommends that women consume 2.2 liters of fluid and men consume 3 liters of fluid per day. While any fluid counts toward total fluid intake, water is the best choice. Drinks with caffeine and carbonation should be avoided.
Improve Urinary Tract Health
Some urinary tract conditions can cause elevations of creatinine in the blood. Examples include kidney infections and urinary obstructions. Getting the proper treatment for these conditions can help to restore creatinine levels to a normal range. Kidney infections may be treated with oral or intravenous antibiotics. Urinary tract obstructions may require surgical intervention. Follow all instructions on how to take prescribed medications or when to report for surgical treatment.
Reduce Blood Pressure
Hypertension, or high blood pressure, is a condition that can contribute to the development of kidney disease and eventual end stage renal disease (ESRD). High blood pressure leads to kidney damage by damaging the blood vessels that supply the kidneys with fresh blood. This can trigger high creatinine levels in the blood. Eat a diet that is low in sodium and get plenty of exercise. If high blood pressure medications are prescribed, carefully follow all dosage instructions.
Manage Diabetes
Diabetes is another medical condition that can lead to kidney damage or kidney failure. Diabetes also damages the blood vessels in the kidneys, making it difficult for the organs to work properly. Diabetics should carefully manage their diabetes to improve high creatinine levels. This means following a diabetic diet and taking insulin and other medications as prescribed. This can help to reduce creatinine levels and also reduces the risk for kidney disease, stroke and other serious medical conditions.
Use of a type of prescription medication for hypertension that's in either of two classes; one class is called an "ACE-inhibitor" and the other “ARB”. Probably all the drugs in these two classes work about the same to protect the kidneys.
Stinging Nettle Seed
1. A study published in the Journal of The American Herbalist Guild, noted that patients who were given stinging nettle seed extract showed a significant decrease in their serum creatinine levels while they were taking the extract and that the effect lasted well after they stopped taking the extract. Stinging nettle seed is possibly the most effective herb available that has been shown to lower these levels.
Cinnamon is a common household spice that helps regulate blood sugar. It has also been used to treat kidney problems especially in diabetics with kidney disorders. Cinnamon helps to enhance the filtration process and to strengthen weak kidneys and thus increases the evacuation rate of creatinine
Dandelion root is known as an herbal diuretic. Diuretics can help inactive kidneys by increasing urination. This increases the output of the kidneys and will dilute the amount of creatinine in the body by increasing the output of the urinary waste at a faster rate.
1. Salvia
2. Researchers have used salvia on patients who were on dialysis for kidney failure and found that it increased the rate of which creatinine was filtered and evacuated from the body. They also noticed that it enhanced the circulation to the kidneys as well.
3. Siberian Ginseng is often used with cinnamon to revitalize the kidneys and to lower creatinine levels. It is known to be very helpful in treating kidney disorders by stimulating the circulation to the kidneys.
Conclusion
4. A high creatinine level is not a problem itself but may be a symptom of an underlying medical problem. It is important that you consult a doctor for proper treatment of the condition. If a high protein diet is the problem then the diet should be modified. It is important that you drink lots of water to help evacuate your system.These herbal treatments are suggested to help lower the creatinine levels in the body and are not a cure to reverse kidney failure.
New study demonstrates bone protein can reverse kidney failure
This new study looked at the role of a molecule called bone morphogenic protein (BMP)- 7 which, in its recombinant form, has been approved by the U.S. Food and Drug Administration for the treatment of bone fractures. I found these web links- BMP7 Human | ProSpec, whichs sells it, www.avivasysbio.com/cc..._t100.htm, www.genwaybio.com/prod...s_id=45166
Earlier studies had revealed that BMP-7 is highly expressed in the kidneys of healthy individuals. 'We wanted to learn if this protein was somehow offering protection against kidney injury,' explains Kalluri.
The investigators used mouse models of chronic renal injury, characterized by the presence of scar tissue known as renal fibrosis; once kidney disease was well-established in the animals, they administered human recombinant BMP-7.
'We found that in the kidneys, BMP-7 reverses a process known as epithelial-to-mesenchymal transition, which generates scar-causing cells known as fibroblasts,' says Kalluri, explaining that BMP-7 first reduces the number of the fibroblast cells, and then replaces the damaged areas of the kidney tubules with healthy epithelial cells.
'In effect,' he adds, 'BMP-7 is decreasing the bad cells [in this context, fibroblasts] and converting them into good cells [in this context, epithelial cells].'
Although therapies exist to slow progression of kidney disease, once it has developed it becomes intractable, eventually leaving patients no alternative but to undergo dialysis.
'The possibility of creating a cost-effective drug that would actually reverse renal injury could significantly reduce the need for dialysis and significantly improve the quality of life for these patients,' says Kalluri.
Study co-authors include BIDMC investigators Michael Zeisberg, M.D., Jun-ichi Hanai, M.D., Hikaru Sugimoto, M.D., Ph.D., Tadanori Mammoto, Ph.D., David Charytan, M.D., and Frank Strutz, M.D.
This study was funded by grants from the National Institutes of Health, Deutsche Forschungsgemeinschaft, and support from the Center for Matrix Biology, BIDMC. Ortho Biotech Products, L.P., is the exclusive licensee of BMP-7.
Beth Israel Deaconess Medical Center is a major patient care, teaching and research affiliate of Harvard Medical School, and ranks third in National Institutes of Health funding among independent hospitals nationwide. BIDMC is clinically affiliated with the Joslin Diabetes Center and is a founding member of the Dana-Farber/Harvard Cancer Center. BIDMC is the official hospital of the Boston Red Sox.
LOW-PROTEIN DIET MAY REVERSE KIDNEY DISEASE
August 30, 1996
NOTE: There is no standard printed diet that can be mailed to you. Dr. Mackenzie Walser, the study's lead author, recommends working with your physician to tailor a diet specific to your needs. Your physician can reach Dr. Walser with any questions at 410-955-3832.
A very low protein diet with amino acid supplements may cure a severe kidney disease in some people, a Johns Hopkins study shows. The results suggest the dietary therapy should be tried before drug treatment for nephrotic syndrome, a chronic kidney disorder that often leads to kidney failure.
Scientists have not solved the paradox of why eating less protein benefits some patients -- sufferers already lose too much protein in their urine, yet restricting dietary protein may help many sufferers, says Mackenzie Walser, M.D., the study's lead author and a professor of pharmacology, molecular sciences and medicine. The study, which was supported in part by the National Institutes of Health, is published in the September issue of the American Journal of Kidney Diseases.
"Five patients remain virtually cured, while only one patient's blood-protein level worsened, " says Walser.
Hopkins researchers put 16 adults on a very low protein diet with essential amino acid or ketoacid supplements for 10 months. Essential amino acids are those amino acids -- building blocks of protein -- that the body can not make. Ketoacids are slightly modified forms of amino acids.
The disorder gradually disappeared during the next three to 15 months in five participants, who started the study before kidney failure became severe, the results show. Four of the five people have resumed normal or nearly normal diets and have remained in remission or near remission for six months to two years. The other 11 participants, who had more advanced kidney failure before starting the study, showed temporary improvement, but all eventually went on dialysis.
Nephrotic syndrome usually is treated with drugs and only modest reduction of dietary protein to reduce the loss of protein in the urine. Severe protein restriction has been avoided for fear of aggravating the low levels of protein in the blood.
In contrast with other treatments, such as steroids or immunosuppressive drugs, the dietary treatment, though often difficult for patients to follow, has no side effects, says Walser. The diet excluded such high-protein foods as meat, fish, poultry, cheese and milk and included supplemental tablets of amino acids, the building blocks of protein.
"We still don't know the mechanism for this surprising result," says Walser. "Evidently, some unidentified component of a regular diet was perpetuating the loss of urinary protein. What's clear from our findings is that the common opinion that kidney disease patients shouldn't be given severely protein-restricted diets needs to be reconsidered."
Hopkins researchers plan to repeat the study with a larger number of patients.
Nephrotic syndrome is marked by damage to the glomeruli, the kidney's filtering units. This causes severe loss of protein from the blood into the urine, severe fluid retention and extremely high blood cholesterol. The syndrome may result from diabetes mellitus, severe high blood pressure or other causes and often leads to the need for dialysis or transplantation.
Previous Hopkins studies have shown that a very low protein diet before dialysis may prolong the lives of some kidney failure patients after they start dialysis and may postpone the start of dialysis for others.
THE BENEFITS OF A BALANCED pH
To restore healthy kidney functioning, you need to reduce dramatically the level of acid waste in your body. A proper alkalinizing diet can help balance your body's pH level. The right combination of vegetable juices can neutralize your body's acids and can dissolve clumps that have started to form kidney stones.
After you body becomes less acidic, you'll need to focus on reducing or eliminating consumption of acid-causing foods and substances. The less acid waste your body produces, the easier time your kidneys will have. Your kidney cells are irreplaceable without drastic intervention, so it's important to start immediately trying to control your body's pH level. Not only will you save your kidneys, you'll experience an overall improvement in your health and reduce your vulnerability to kidney diseases.
.
People with IgA nephropathy may develop high cholesterol. By watching their diet and taking medicine, they can help lower their cholesterol level. Lowering cholesterol may help slow kidney damage.
Medicines such as prednisone may help treat IgA nephropathy. Prednisone belongs to a class of medicines called corticosteroids, which can have harmful side effects. In research studies, fish oil supplements containing omega 3 fatty acids also slowed kidney damage in some patients. Vitamin E may help lower protein in the urine but not blood. One of the newer immunosuppressive agents called mycophenolate mofetil (MMF) is also being tested in treating IgA nephropathy.
My wife has kidney issues. When I met her they only function at around 50%. There are those who say you can repair kidneys but I think that’s BS. I made her this list a few years ago and she bought her most of these supplements. Her Kidneys are now at 75%. So I’m sure they will help you boost your kidneys.
(CoQ10) can improve kidney function and reduce the need for dialysis.
Coenzyme Q10 Beneficial for People with Kidney Failure By Alan R. Gaby, MD Healthnotes Newswire (July 17, 2003)Supplementing with coenzyme Q10 (CoQ10) can improve kidney function and reduce the need for dialysis in people with severe, chronic kidney (renal) failure, according to a study in the Journal of Nutritional and Environmental Medicine (2003;13:13–22). If this study is confirmed, CoQ10 therapy will represent a major breakthrough in the treatment of a disorder that is both debilitating and a significant drain on our healthcare resources.
In severe, chronic renal failure, the kidneys lose their capacity to excrete waste products of metabolism and other toxins. Consequently, these substances accumulate in the body, leading to various problems such as fatigue, loss of appetite, anemia, disorders of the nervous system, heart disease, and ultimately death. Common causes of chronic renal failure include diabetes, hardening of the arteries (atherosclerosis), and high blood pressure.
People with advanced renal failure are usually treated three or more times per week by a procedure called dialysis, in which a machine is used to filter the toxins from the blood. While dialysis can prolong life in people with advanced renal failure, it is associated with a number of adverse effects, including low blood pressure, infection, and worsening heart disease. In addition, dialysis is expensive, costing more than $50,000 per year at some centers. Any treatment that has the potential to improve kidney function and reduce the need for dialysis would be a significant advance.
In the new study, 97 people (average age, 48 years) with chronic renal failure were randomly assigned to receive a placebo or 60 mg of CoQ10 by mouth three times per day for 12 weeks. Among the 45 participants who were already receiving dialysis, supplementation with CoQ10 resulted in an improvement in various measures of kidney function, including serum creatinine (29% improvement) and blood urea nitrogen (9% improvement). In contrast, kidney function tended to worsen in the placebo group, and the differences between CoQ10 and placebo were statistically significant. CoQ10 also produced significant improvements relative to placebo among the participants who were not receiving dialysis. By the end of the study, the number of people requiring dialysis had decreased from 21 to 12 in the CoQ10 group, but remained unchanged at 24 in the placebo group.
These results suggest that treatment with CoQ10 improves kidney function and reduces the need for dialysis in people with chronic renal failure. Because CoQ10 has the potential to revolutionize the treatment of chronic renal failure, a large-scale, long-term study should be initiated as soon as possible.
Alan R. Gaby, MD, an expert in nutritional therapies, testified to the White House Commission on CAM upon request in December 2001. Dr. Gaby served as a member of the Ad-Hoc Advisory Panel of the National Institutes of Health Office of Alternative Medicine. He is the author of Preventing and Reversing Osteoporosis (Prima, 1994), and co-author of The Natural Pharmacy, 2nd Edition (Healthnotes, Prima, 1999),
CoQ10 (Coenzyme Q10) and Renal Failure Chronic renal failure (CRF) is the progressive loss of kidney function.
Chronic Renal Insufficiency (CRI) is the early stage, when the kidneys no longer function properly but do not yet require dialysis.
CoQ10 was studied in a small pilot study involving 21 patients with chronic renal failure. Researchers administered CoQ10 to 11 of the subjects while 10 received a placebo capsule. To be included in the study patients had to have a creatinine level of 5 mg/dl or above. After 4 weeks, the subjects receiving CoQ10 had significant decreases in serum creatinine and urea while creatinine clearance significantly increased. At the end of the 4 week study the number of patients on dialysis was significantly less in the CoQ10 group. 36.2% of the patients in the CoQ10 group were on dialysis at the end of the study while 90.0% of the placebo group were on dialysis at the end of the study.
An increase in blood antioxidant levels and a significant decrease in indicators of oxidative stress were noted by the study group. (J Nutr Environ Med, 2000; 10: 281-288)
"Randomized, Double-Blind Placebo-Controlled Trial of Coenzyme Q10 in Chronic Renal Failure: Discovery of a New Role," Singh RB, Khanna HK, Niaz MA, J Nutr Environ Med, 2000;10:281-288.36843
Yes, baking soda really did help some patients with chronic kidney disease and metabolic acidosis. In the Royal London Hospital study, reported in the Journal of the American Society of Nephrology, participants took a small daily dose of sodium bicarbonate (baking soda) in tablet form. sodium bicarb tablets 1300mg twice a day
Herbs
Ganoderma Lucidum and Cordyceps Sinensis
Coq10 for reversing kidney disease - The Studies
One study looked at 15 patients who were "uremic' - meaning they at the end stage of renal failure where at least two thirds of the kidney cells (nephrons) have been destroyed. And compared their coq10 levels with the control group of 10, as well as the coq10 levels of 48 patients on chronic hempdialysis, and found the coq10 levels were significantly lower in the group on hemodialysis and the uremic patients compared to the control group. This study did not involve any supplementation, merely looked at the body's coq10 levels.
One study which did measure the effect of supplementation with coq10 in patients with chronic renal failure found that those in this study who were receiving the coq10 and were on dialysis, had improved kidney function. At the end of the study, the number of people needing dialysis that had been using coq10 was reduced - from 21 to 12, which is a huge improvement. Especially considering there was no reduction in the number needing dialysis in the group who received the placebo. So with regards coq10 for reversing kidney disease, the question is still out, after all we don't know from this one study what mechanisms of action the coq10 helped. Kidney disease is a result of the death of kidney cells, and there was no mention of coq10 regenerating those cells. But it is certainly very promising in managing and improving the health of those with kidney disease.
References: C Porth, Pathophysiology: Concepts of Altered Health States 4th Ed. (J.BLippincott Company, 1994)
Renal Shield
Investigations have shown that cordyceps sinensis could enhance kidney functions, shielding it from impairment caused by nephrotoxic chemicals. Research conveyed that the condition of patients with chronic renal failure enhanced in as little as 30 days. In fact, a distinguished regeneration of renal tubular cells was obtained in subjects provided with cordyceps sinensis. A scientific analysis published in Nephrology Dialysis Transplantation reports that three grams of cordyceps sinensis per day is adequate to shield the kidney against cyclosporine-instigated nephrotoxicity. The research, implemented on 69 kidney transplant patients, proffered cordyceps sinensis as a catalyst in the diminution of cyclosporine instigated renal toxicity, thus shielding the kidney to nephritis.
Cordyceps (Cordyceps sinensis), a fungus found growing in caterpillar larvae of certain moths, has long been valued as a kidney tonic in China (Zhu, Halpern, & Jones, 1998). One study in 61 patients with lupus nephritis showed that a combination of 2 g to 4 g of cordyceps powder together with 0.6 grams of artemisinin from the plant Artemisia annua for 3 years improved kidney function as measured by creatinine clearance (Lu, 2002). Another study found that cordyceps lessened the nephrotoxicity of cyclosporine in kidney transplant patients (Xu, Huang, Jiang, Xu, & Mi, 1995). An anti-oxidant protective mechanism was postulated for this protective effect. The Japanese traditional remedy Sairei-to, a 12 herb mixture, has shown in human and animal studies to protect the kidney in gentamicin renal toxicity, IgA nephropathy, and lupus nephritis (Ohno et al., 1993). Another study in rats showed that extracts from the root of the plant Salvia miltiorriza (Danshen) along with fructose 1-6 diphosphate prevented the decline of renal cortical Na-K-ATPase activity induced by ischemia and gentamicin (Lu & Li, 1989). Further, extracts of the plant Herniaria hirsute inhibit calcium oxalate crystal aggregation and thus could be useful in preventing kidney stone formation (Atmani & Khan, 2000). In summary, there seems to be many potentially protective medicinal plants and supplements that may protect the kidney perhaps via acting primarily as anti-oxidants (see Table 2 ).
In terms of creatinine levels: yes, there is an easy way to get your creatinine levels down, don't work out and lie in bed for as long as you can. Once your muscle mass is lost, your creatinine will also go down. The point I'm trying to make is that creatinine levels themselves are only indirectly assoiated with kidney function. Depending on how much muscle you have, you are constantly producing creatinine and spilling it in to your blood and then your urine
Improving Creatinine Levels
Creatinine - Serum AdsLowering Creatinine LevelsDiabetic Blood Sugar LevelTriglycerides LevelsDiabetes Glucose LevelsHigh Creatinine
Creatinine is a waste product that forms when creatine is broken down. The kidneys are responsible for eliminating this waste product from the body, so blood creatinine levels are an important indicator of kidney function. If blood creatinine levels are too high, it can indicate a decline in kidney function. There are some steps that can improve creatinine levels and reduce the workload on the kidneys.
Reduce Protein Intake
Creatine is a substance that is found in high-protein animal products such as red meat and poultry. When creatine is broken down for energy, creatinine is produced. One way to improve blood creatinine levels is to reduce the amount of protein that is eaten in the diet. When consumption of these high-protein foods declines, there is less creatine available to break down into creatinine. Eating less protein can also reduce the amount of work the kidneys have to do to filter the blood and remove waste products from the body.
Increase Fluid Intake
While high creatinine levels can indicate a serious medical condition, dehydration can also cause an increase in serum creatinine. Increasing fluid intake can help avoid dehydration and eliminate the possibility of elevating creatinine levels. The Institute of Medicine recommends that women consume 2.2 liters of fluid and men consume 3 liters of fluid per day. While any fluid counts toward total fluid intake, water is the best choice. Drinks with caffeine and carbonation should be avoided.
Improve Urinary Tract Health
Some urinary tract conditions can cause elevations of creatinine in the blood. Examples include kidney infections and urinary obstructions. Getting the proper treatment for these conditions can help to restore creatinine levels to a normal range. Kidney infections may be treated with oral or intravenous antibiotics. Urinary tract obstructions may require surgical intervention. Follow all instructions on how to take prescribed medications or when to report for surgical treatment.
Reduce Blood Pressure
Hypertension, or high blood pressure, is a condition that can contribute to the development of kidney disease and eventual end stage renal disease (ESRD). High blood pressure leads to kidney damage by damaging the blood vessels that supply the kidneys with fresh blood. This can trigger high creatinine levels in the blood. Eat a diet that is low in sodium and get plenty of exercise. If high blood pressure medications are prescribed, carefully follow all dosage instructions.
Manage Diabetes
Diabetes is another medical condition that can lead to kidney damage or kidney failure. Diabetes also damages the blood vessels in the kidneys, making it difficult for the organs to work properly. Diabetics should carefully manage their diabetes to improve high creatinine levels. This means following a diabetic diet and taking insulin and other medications as prescribed. This can help to reduce creatinine levels and also reduces the risk for kidney disease, stroke and other serious medical conditions.
Use of a type of prescription medication for hypertension that's in either of two classes; one class is called an "ACE-inhibitor" and the other “ARB”. Probably all the drugs in these two classes work about the same to protect the kidneys.
Stinging Nettle Seed
1. A study published in the Journal of The American Herbalist Guild, noted that patients who were given stinging nettle seed extract showed a significant decrease in their serum creatinine levels while they were taking the extract and that the effect lasted well after they stopped taking the extract. Stinging nettle seed is possibly the most effective herb available that has been shown to lower these levels.
Cinnamon is a common household spice that helps regulate blood sugar. It has also been used to treat kidney problems especially in diabetics with kidney disorders. Cinnamon helps to enhance the filtration process and to strengthen weak kidneys and thus increases the evacuation rate of creatinine
Dandelion root is known as an herbal diuretic. Diuretics can help inactive kidneys by increasing urination. This increases the output of the kidneys and will dilute the amount of creatinine in the body by increasing the output of the urinary waste at a faster rate.
1. Salvia
2. Researchers have used salvia on patients who were on dialysis for kidney failure and found that it increased the rate of which creatinine was filtered and evacuated from the body. They also noticed that it enhanced the circulation to the kidneys as well.
3. Siberian Ginseng is often used with cinnamon to revitalize the kidneys and to lower creatinine levels. It is known to be very helpful in treating kidney disorders by stimulating the circulation to the kidneys.
Conclusion
4. A high creatinine level is not a problem itself but may be a symptom of an underlying medical problem. It is important that you consult a doctor for proper treatment of the condition. If a high protein diet is the problem then the diet should be modified. It is important that you drink lots of water to help evacuate your system.These herbal treatments are suggested to help lower the creatinine levels in the body and are not a cure to reverse kidney failure.
New study demonstrates bone protein can reverse kidney failure
This new study looked at the role of a molecule called bone morphogenic protein (BMP)- 7 which, in its recombinant form, has been approved by the U.S. Food and Drug Administration for the treatment of bone fractures. I found these web links- BMP7 Human | ProSpec, whichs sells it, www.avivasysbio.com/cc..._t100.htm, www.genwaybio.com/prod...s_id=45166
Earlier studies had revealed that BMP-7 is highly expressed in the kidneys of healthy individuals. 'We wanted to learn if this protein was somehow offering protection against kidney injury,' explains Kalluri.
The investigators used mouse models of chronic renal injury, characterized by the presence of scar tissue known as renal fibrosis; once kidney disease was well-established in the animals, they administered human recombinant BMP-7.
'We found that in the kidneys, BMP-7 reverses a process known as epithelial-to-mesenchymal transition, which generates scar-causing cells known as fibroblasts,' says Kalluri, explaining that BMP-7 first reduces the number of the fibroblast cells, and then replaces the damaged areas of the kidney tubules with healthy epithelial cells.
'In effect,' he adds, 'BMP-7 is decreasing the bad cells [in this context, fibroblasts] and converting them into good cells [in this context, epithelial cells].'
Although therapies exist to slow progression of kidney disease, once it has developed it becomes intractable, eventually leaving patients no alternative but to undergo dialysis.
'The possibility of creating a cost-effective drug that would actually reverse renal injury could significantly reduce the need for dialysis and significantly improve the quality of life for these patients,' says Kalluri.
Study co-authors include BIDMC investigators Michael Zeisberg, M.D., Jun-ichi Hanai, M.D., Hikaru Sugimoto, M.D., Ph.D., Tadanori Mammoto, Ph.D., David Charytan, M.D., and Frank Strutz, M.D.
This study was funded by grants from the National Institutes of Health, Deutsche Forschungsgemeinschaft, and support from the Center for Matrix Biology, BIDMC. Ortho Biotech Products, L.P., is the exclusive licensee of BMP-7.
Beth Israel Deaconess Medical Center is a major patient care, teaching and research affiliate of Harvard Medical School, and ranks third in National Institutes of Health funding among independent hospitals nationwide. BIDMC is clinically affiliated with the Joslin Diabetes Center and is a founding member of the Dana-Farber/Harvard Cancer Center. BIDMC is the official hospital of the Boston Red Sox.
LOW-PROTEIN DIET MAY REVERSE KIDNEY DISEASE
August 30, 1996
NOTE: There is no standard printed diet that can be mailed to you. Dr. Mackenzie Walser, the study's lead author, recommends working with your physician to tailor a diet specific to your needs. Your physician can reach Dr. Walser with any questions at 410-955-3832.
A very low protein diet with amino acid supplements may cure a severe kidney disease in some people, a Johns Hopkins study shows. The results suggest the dietary therapy should be tried before drug treatment for nephrotic syndrome, a chronic kidney disorder that often leads to kidney failure.
Scientists have not solved the paradox of why eating less protein benefits some patients -- sufferers already lose too much protein in their urine, yet restricting dietary protein may help many sufferers, says Mackenzie Walser, M.D., the study's lead author and a professor of pharmacology, molecular sciences and medicine. The study, which was supported in part by the National Institutes of Health, is published in the September issue of the American Journal of Kidney Diseases.
"Five patients remain virtually cured, while only one patient's blood-protein level worsened, " says Walser.
Hopkins researchers put 16 adults on a very low protein diet with essential amino acid or ketoacid supplements for 10 months. Essential amino acids are those amino acids -- building blocks of protein -- that the body can not make. Ketoacids are slightly modified forms of amino acids.
The disorder gradually disappeared during the next three to 15 months in five participants, who started the study before kidney failure became severe, the results show. Four of the five people have resumed normal or nearly normal diets and have remained in remission or near remission for six months to two years. The other 11 participants, who had more advanced kidney failure before starting the study, showed temporary improvement, but all eventually went on dialysis.
Nephrotic syndrome usually is treated with drugs and only modest reduction of dietary protein to reduce the loss of protein in the urine. Severe protein restriction has been avoided for fear of aggravating the low levels of protein in the blood.
In contrast with other treatments, such as steroids or immunosuppressive drugs, the dietary treatment, though often difficult for patients to follow, has no side effects, says Walser. The diet excluded such high-protein foods as meat, fish, poultry, cheese and milk and included supplemental tablets of amino acids, the building blocks of protein.
"We still don't know the mechanism for this surprising result," says Walser. "Evidently, some unidentified component of a regular diet was perpetuating the loss of urinary protein. What's clear from our findings is that the common opinion that kidney disease patients shouldn't be given severely protein-restricted diets needs to be reconsidered."
Hopkins researchers plan to repeat the study with a larger number of patients.
Nephrotic syndrome is marked by damage to the glomeruli, the kidney's filtering units. This causes severe loss of protein from the blood into the urine, severe fluid retention and extremely high blood cholesterol. The syndrome may result from diabetes mellitus, severe high blood pressure or other causes and often leads to the need for dialysis or transplantation.
Previous Hopkins studies have shown that a very low protein diet before dialysis may prolong the lives of some kidney failure patients after they start dialysis and may postpone the start of dialysis for others.
THE BENEFITS OF A BALANCED pH
To restore healthy kidney functioning, you need to reduce dramatically the level of acid waste in your body. A proper alkalinizing diet can help balance your body's pH level. The right combination of vegetable juices can neutralize your body's acids and can dissolve clumps that have started to form kidney stones.
After you body becomes less acidic, you'll need to focus on reducing or eliminating consumption of acid-causing foods and substances. The less acid waste your body produces, the easier time your kidneys will have. Your kidney cells are irreplaceable without drastic intervention, so it's important to start immediately trying to control your body's pH level. Not only will you save your kidneys, you'll experience an overall improvement in your health and reduce your vulnerability to kidney diseases.
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People with IgA nephropathy may develop high cholesterol. By watching their diet and taking medicine, they can help lower their cholesterol level. Lowering cholesterol may help slow kidney damage.
Medicines such as prednisone may help treat IgA nephropathy. Prednisone belongs to a class of medicines called corticosteroids, which can have harmful side effects. In research studies, fish oil supplements containing omega 3 fatty acids also slowed kidney damage in some patients. Vitamin E may help lower protein in the urine but not blood. One of the newer immunosuppressive agents called mycophenolate mofetil (MMF) is also being tested in treating IgA nephropathy.
