Kidney Supps

[whacked]

This is not directed at anyone …

There are plenty of people (regular folks, MD’s, DC’s, PhD’s, Natruopaths, Fitness Guru’s, Herbalists, etc) hyping up their products and ripping people off by overcharging.

That doesn’t mean the actual product or the ingredients in the product will not or do not work.

Let’s not be myopic with our assessment of a product’s efficacy; while reviewing things that may confer a benefit / help us.

We don’t have to buy anything from anyone in particular and we SHOULD look for the best price for a comparable product as well; but to throw the baby out with the bathwater, is just not prudent practice here.

Know who did this for decades? MD’s. Laughed at every supplement out there said it was all snake oil as they force fed us toxic pharmaceutical alternatives.

Can you imagine convincing a highly specialized Nephrologist (MD) 10 years ago that some poorly researched ambiguous herb named astragulus would improve kidney function?

In my opinion, there’s goods and bads in almost every discipline of medicine.

We just have to be discerning (and unfortunately take some chances); and be prepared to lose some loot along the way as well due to the lack of regs, as we play guinea pig.

 

[whacked]

Side note. I’m also doing research on Dan Shen and Thunder God Vine (great name for an herb lol) for Kidney health.

Looks interesting but who the heck knows.

Simply sharing what I’m finding that’s all.

Salvia miltiorrhiza, also known as danshen in Chinese, may help improve kidney function and slow the progression of chronic kidney disease (CKD). Here are some ways it may help:

• Reduces kidney index
  In animal studies, S. miltiorrhiza reduced the kidney index, which is the ratio of kidney weight to body weight.
• Reduces serum creatinine and blood urea nitrogen
  In animal studies, S. miltiorrhiza reduced serum creatinine and blood urea nitrogen.
• Reduces 24-hour urine protein and albumin
  In animal studies, S. miltiorrhiza reduced 24-hour urine protein and albumin.
• Alleviates renal pathological damage
  In animal studies, S. miltiorrhiza alleviated renal pathological damage.

S. miltiorrhiza may also have other health benefits, including:

• Protecting the heart: S. miltiorrhiza may protect the heart during pathological processes like myocardial ischemia and infarction.
  
  
• Treating cardiovascular and cerebrovascular diseases: S. miltiorrhiza is used to treat cardiovascular and cerebrovascular diseases, especially in Asia.
  
  
• Treating diabetes: S. miltiorrhiza may have anti-diabetic activities.
  
  
• Treating hypertension: S. miltiorrhiza may have anti-hypertensive effects.

Conclusions​

Salvia miltiorrhiza or its extracts Salvianolate and Tanshinone, as a complementary therapy to conventional medicine, presents potential impacts to improve kidney functions and delay the progression of CKD without obvious adverse effects. However, the certainty of the evidence and the risk of bias are suboptimal and further clinical studies are still required to determine the underlying effects.

Efficacy and Safety of Salvia miltiorrhiza for Treating Chronic Kidney Diseases: A Systematic Review and Meta-Analysis - PMC

This meta-analysis evaluated the effects and potential harms of Salvia miltiorrhiza or its extracts Salvianolate and Tanshinone for the treatment of population with a chronic kidney disease (CKD). We searched for the randomized clinical trials ...

pmc.ncbi.nlm.nih.gov

 

[whacked]

More ideas for Marssel and others w suboptimal kidney function …

Kidney Function

My eGFR isn’t great and my Cystatin is “ok” (could be better) so I’m always looking for support. 1. We already have Vitamin Shoppe Astragalus thanks to DC. 2. I recently read some articles on BCP-157 and TB-500 that may confer benefits. 3. Also just stumbled across PHGPE (Protein...

www.professionalmuscle.com

 

[aHarness]

@bbxtreme do you potentially have insight on SS-31 for kidneys?

 

[bbxtreme]

@bbxtreme do you potentially have insight on SS-31 for kidneys?

In theory it “should” given it increases mitochondrial function. I know thus far it’s being used for heart failure.

If one were to use it they would want to ensure it’s paired with other things to support mitochondrial energy like coq10 and NAD+.

I think people would be surprised though if they did simple things like short runs or methylene blue, 800mg coq10 daily and NAD+ just how well the body would heal without having to explore peptides.

Add that on top of 4-6g of astragalus daily with a good lifestyle and the body will usually begin to heal again.

 

[aHarness]

In theory it “should” given it increases mitochondrial function. I know thus far it’s being used for heart failure.

If one were to use it they would want to ensure it’s paired with other things to support mitochondrial energy like coq10 and NAD+.

I think people would be surprised though if they did simple things like short runs or methylene blue, 800mg coq10 daily and NAD+ just how well the body would heal without having to explore peptides.

Add that on top of 4-6g of astragalus daily with a good lifestyle and the body will usually begin to heal again.

Interesting, I didn’t know MB had health benefits. I honestly thought it was just for energy in a stim pathway.

As for SS31, I just specifically brought that up as I did see this

SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease - PMC

Mitochondria are essential for eukaryotic cell activity and function, and their dysfunction is associated with the development and progression of renal diseases. In recent years, there has been a rapid development in mitochondria-targeting ...

pmc.ncbi.nlm.nih.gov

Among some other studies regarding it and kidney health.

 

[whacked]

Interesting, I didn’t know MB had health benefits. I honestly thought it was just for energy in a stim pathway.

As for SS31, I just specifically brought that up as I did see this

SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease - PMC

Mitochondria are essential for eukaryotic cell activity and function, and their dysfunction is associated with the development and progression of renal diseases. In recent years, there has been a rapid development in mitochondria-targeting ...

pmc.ncbi.nlm.nih.gov

Among some other studies regarding it and kidney health.

Cool addition to this thread!

If anything, SS-31 seems to impart a benefit in a different / unique way via mitochondrial biogenesis and restoration; compared to everything else mentioned thus far - other than MB. It also has a host of other very cool benefits.

Side note. I looked into MB a year ago and while it has some fascinating properties, it has some “potential” concerns; albeit when dosing is higher (MOAI related). It’s a “weird” cult like status type substance that some swear by (almost in panacea mode) while a small minority ring the alarm bells for concerns. In some way, it reminds me of DNP where the dose is the poison, and most praise it when taken responsibly, but there a certain fear surrounds its use.

 

[whacked]

@ Marssel

Fascinating (intelligent) Lipidologist explains a novel approach to improving eGFR significantly. Gives into the value of Cystatin > eGFR.

Cliff notes: 80 year old patient went from 19 (only 4 points to mandatory dialysis) to 46 … same year … then eventually 61. Crazy. Patient lived to 94.

He is big on these “unsexy” supps:

-Niacin (high dose)
-Fish Oil
-Sodium Bicarbonate

II. In the 2nd video, he discuss Niacin at length.

III. In the 3rd video, he also praises Thunder God Vine Root (Tripterygium Wilfordii) for improving kidney function and calcium in the arteries so a welcomed side benefit to reduce CVD risk.

 

[bbxtreme]

Cool addition to this thread!

If anything, SS-31 seems to impart a benefit in a different / unique way via mitochondrial biogenesis and restoration; compared to everything else mentioned thus far - other than MB. It also has a host of other very cool benefits.

Side note. I looked into MB a year ago and while it has some fascinating properties, it has some “potential” concerns; albeit when dosing is higher (MOAI related). It’s a “weird” cult like status type substance that some swear by (almost in panacea mode) while a small minority ring the alarm bells for concerns. In some way, it reminds me of DNP where the dose is the poison, and most praise it when taken responsibly, but there a certain fear surrounds its use.

Spot on with MB. You don’t run it very long or very high. It’s very beneficial when used “right.”

 

[whacked]

Niacin ~ although not overly “sexy” is pretty dang impressive.

I.

https://journals.physiology.org/doi/full/10.1152/ajprenal.00126.2009

II.

Frontiers | U-shaped association between dietary niacin intake and chronic kidney disease among US elderly: a nationwide cross-sectional study

Background: In addition to hypertension or diabetes, elderly people are also considered one of the high-risk groups for chronic kidney disease (CKD). Althoug...

www.frontiersin.org

III.

https://www.sciencedirect.com/science/article/abs/pii/S0272638615000207

IV.

https://www.ajkd.org/article/S0272-6386(10)00834-6/fulltext

 

[whacked]

Update (in no particular order) as of 12/14/24:

These produced impressive results via Google research.

I’m only contributing notes on items I researched and read worthwhile data on.

I am on #1 … and plan to add #5 as soon as my order arrives and maybe #2 and/or #6 “soon” as well.

1. Astragalus (Vitamin Shoppe)

2. TUDCA

3. Vitamin B-3 (Niacin)

4. SS-31

5. Rehmannia (Rehmannia Glutinosa)
TCM/Traditional Chinese Medicine

6. Thunder god vine
TCM/Traditional Chinese Medicine

7. DanShen (Salvia Miltiorrhiza) aka Chinese Red Sage
TCM/Traditional Chinese Medicine

8. Poria Cocos
TCM/Traditional Chinese Medicine

When Diagnosed with CKD:
Sodium BiCarbonate

Support:
Grapeseed Extract
Bromelain
Pycnogenol (Pine Bark)

 

[youngtuck713]

i think NAC is supposed to help with kidneys and liver, but I may be wrong

 

[youngtuck713]

TUDCA as well, which is what I use daily

 

[thehogsters]

Now Kidney cleanse. 2 every morning. Makes me pee like a race horse till after lunch.