Stewie
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I have a question for you as well. Sorry dude...you are just well versed with this stuff so you get the questions and honestly a lot of kidney docs don't seem to understand cystatin c that well from what I've noticed.
I saw my GP and Nephrologist today and they are both thrown by cystatin c numbers. They are always in the reference range but here is a summary after reviewing all tests over 5ish years...
19 Total tests completed
11 of them between .79-.85 (reference range .63-1.16)
8 of the tests were .31-.55
the 8 tests were dispersed evenly. Meaning, I may have 3 tests in the .81 range and then boom I get a 0.41.
I can't find any study of any even single person with cystatin c that low so my nephrologist is thinking it has to do with my thyroid and we throw those outliers away. I take 100mcg of synthroid and have been on that many years. So, it is controlled but my TSH does fluctuate.
any general thoughts? I can't find a single example of cystatin c that low or a reason it would drop like that other than thyroid. I do not take hgh.
It 'may' be that you have a high clearance rate of urinary Cystatin C. Out of curiosity you could ask your neph to pull a urinary Cystatin C along with serum to access the ratio. I don't know what a normal ratio would be, although I would like to believe your neph can readily determine this information.
Otherwise, I dunno.