Lab results, I'm worried

[AllLoadedUp]

So my doc did a complete metabolic today.

BUN-42 HIGH
Creatinine-1.66 HIGH
eGFR2021-49 LOW

The eGFR2021 is what has me worried. That seems way low from the readings. The way I read that is "mild to moderate kidney disease" based what I've read online. This worries me a lot.

He also did a Microalbumin Panel results are

MA/CR -16.4 which is in range
UMA -2.93 range is 0.00-1.90 so this one is pretty high
UCR- 178 I guess that's normal as it doesn't give a range.

So what do you guys think? I've not heard back from the doc yet. But I'm guessing I will based on the kidney reading. I fasted over 10 hrs before the test. My eGFR a year ago was 67. So within range based on the test.

 

[Fleezy]

Were you properly hydrated?

How long before the test was your last training session?

Typical blood pressure readings?

 

[AllLoadedUp]

I should add I've been on Ammoxicilin and Prednisone for the last 10 days. Have some Bronchitis. Not sure if those would be putting a lot of added stress on my kidneys or not.

 

[AllLoadedUp]

Were you properly hydrated?

How long before the test was your last training session?

Typical blood pressure readings?

I woke up and went to the doc. Didn't have any water this morning before the test. I worked out yesterday. My blood pressure today was 114/58. That's a typical reading for me. I take meds for blood pressure. I should have had some water this morning but I got up and went for the bloodwork.

 

[aHarness]

I woke up and went to the doc. Didn't have any water this morning before the test. I worked out yesterday. My blood pressure today was 114/58. That's a typical reading for me. I take meds for blood pressure. I should have had some water this morning but I got up and went for the bloodwork.

You were dehydrated. Retest with proper hydration before, and grab a cystatin c too.

 

[AllLoadedUp]

You were dehydrated. Retest with proper hydration before, and grab a cystatin c too.

You are probably right. It just worries me to see my reading drop that much in a year. I've never seen that before.

 

[specter]

You are probably right. It just worries me to see my reading drop that much in a year. I've never seen that before.

The meds arent helping either, hydrate and retest.

 

[Fleezy]

take 5 days off training, hydrate, and retest*

 

[GetYucked]

Amazes me that doctors don't tell you to hydrate before these tests; you weren't hydrated, you can't rely on the numbers for a few of these readings.

But I guess, it doesn't amaze me when I have a female client who uses PED's, and her doctor thinks there is no need to pull any of those hormones lol.

Lack of hydration will show elevated BUN, creatinine and a lower eGFR.

Pull your Cystatin C and measure eGFR on that. https://www.kidney.org/professionals/gfr_calculator

 

[Stewie]

Prednisolone can muck with your osmolality, ultimately affecting your electrolyte balance. In which could acutely increase your BUN and creatinine (catabolic effects). Amoxicillin can also acutely increase BUN/Cr.

I'm sure your treating clinician is aware of this.

 

[cage99]

If you’re not already taking astragulus I would add it into your daily supplement regime.

Cage

 

[Mufasa123]

Cystatin-c test is better esp for athletes and people holding a lot of muscle. My egfr on creatinine is always high 50s...its 90s on cystatin-c. Just started astralugus 8g per day as well based on forum recs.

Definitely hydrate. Fucks with my bloods hugely to the point I'm going to start doing afternoon bloods as even waking up hours early and drinking a ton doesn't help as much (better results in early AM staying up all night...stupid but my hydration swings are big I guess).

 

[AllLoadedUp]

I went back and looked as far back as 2016 and my BUN has always been High. The reference range is like 6-26 (ng/dl). Mine has always been higher than the reference range. Its never been 42 though. My creatinine and eGFR has always been within the reference range. I never really worried about just the BUN being elevated and my doctor never said anything before. I have a new doctor now. He hasn't written anything in his notes yet about the lab results. So I'm gonna wait till he does and then go from there. I'm dropping all the antibiotics today and the prednisone I didn't take any of that yesterday either. Just go from there.

 

[AllLoadedUp]

One thing that is confusing to me is that my MA/CR ratio is normal. Which from what I read means normal kidney function. But according to the Creatinine and eGFR as well as my BUN are all high which indicates a problem. Maybe someone on here can interpret that all better than I can. I'll wait to see what the doc says.

 

[GetYucked]

One thing that is confusing to me is that my MA/CR ratio is normal. Which from what I read means normal kidney function. But according to the Creatinine and eGFR as well as my BUN are all high which indicates a problem. Maybe someone on here can interpret that all better than I can. I'll wait to see what the doc says.

I can't speak on the impact of your medications, but the hydration aspect can swing things from ugly to good, and good to ugly.

I see in another post you say you weren't hydrated, and you're worried about the drop so quick. I wouldn't be, these values are a moment in time "look inside", and if you were dehydrated at that time, the bloods are going to show that.

The creatinine, BUN, and eGFR are 100% impacted by lack of fluids. Quick search leads me to believe the MA/CR ratio will also be influenced by this, as the numerator and denominator are albumin and creatinine, respectively.

I had a client with this exact issue. Lack of fluids before testing. Tested again shortly after with the proper protocol; BUN and creatinine back down, eGFR back up. We pulled cystatin-C and a couple other values as well to ensure we weren't missing anything. What I got back looked like bloodwork of someone natural outside of test, free test, estrogen; and everything that was out of range, was now in range.

I have all my clients take three days off all training, and 1.5-2 liters water before testing.

 

[AllLoadedUp]

I can't speak on the impact of your medications, but the hydration aspect can swing things from ugly to good, and good to ugly.

I see in another post you say you weren't hydrated, and you're worried about the drop so quick. I wouldn't be, these values are a moment in time "look inside", and if you were dehydrated at that time, the bloods are going to show that.

The creatinine, BUN, and eGFR are 100% impacted by lack of fluids. Quick search leads me to believe the MA/CR ratio will also be influenced by this, as the numerator and denominator are albumin and creatinine, respectively.

I had a client with this exact issue. Lack of fluids before testing. Tested again shortly after with the proper protocol; BUN and creatinine back down, eGFR back up. We pulled cystatin-C and a couple other values as well to ensure we weren't missing anything. What I got back looked like bloodwork of someone natural outside of test, free test, estrogen; and everything that was out of range, was now in range.

I have all my clients take three days off all training, and 1.5-2 liters water before testing.

Yeh I stopped eating around 2:30am in the morning. The blood and urine sample were taken about 1pm. So it was like a 10.5-11 hr window. When I woke that morning I didn't have any water either. Straight to the doc and had my appt. I've never stopped training even a day before bloods in the past. I will do that when I retest. Plus I'm gonna get a cystatin-c test from the doc. He also did a Complete Blood Count with Differential. Everything was normal but my MPV. Which has to do with your blood platelet size. Mine was slightly low. Nothing to really worry about I don't think.

Like I said the MA/CR was normal range. But the others elevated. Seems like both would be out of whack. Just see what the doc says.

 

[aHarness]

Yeh I stopped eating around 2:30am in the morning. The blood and urine sample were taken about 1pm. So it was like a 10.5-11 hr window. When I woke that morning I didn't have any water either. Straight to the doc and had my appt. I've never stopped training even a day before bloods in the past. I will do that when I retest. Plus I'm gonna get a cystatin-c test from the doc. He also did a Complete Blood Count with Differential. Everything was normal but my MPV. Which has to do with your blood platelet size. Mine was slightly low. Nothing to really worry about I don't think.

Like I said the MA/CR was normal range. But the others elevated. Seems like both would be out of whack. Just see what the doc says.

Yeah man try and relax. If your readings haven’t been trending down odds are you didn’t randomly have kidney failure or anything. Just wait and see what the cystatin c says, I’m sure you’re okay

 

[Golden]

Hydration level and distance from last training session makes a massive difference to blood results. You'll never get a proper picture if you don't drink enough or take enough time off after training.

 

[GetYucked]

Yeh I stopped eating around 2:30am in the morning. The blood and urine sample were taken about 1pm. So it was like a 10.5-11 hr window. When I woke that morning I didn't have any water either. Straight to the doc and had my appt. I've never stopped training even a day before bloods in the past. I will do that when I retest. Plus I'm gonna get a cystatin-c test from the doc. He also did a Complete Blood Count with Differential. Everything was normal but my MPV. Which has to do with your blood platelet size. Mine was slightly low. Nothing to really worry about I don't think.

Like I said the MA/CR was normal range. But the others elevated. Seems like both would be out of whack. Just see what the doc says.

The MA/CR could be in a normal range because it's a ratio, which can be misleading. I've not looked at what direction dehydration drives MA or CR, but it could be the case where the ratio is unchanged, but the underlying values are way off.

Ignoring what the variables are, look at it this incredibly made up scenario:

Compound A and Compound B are a perfect mix at a ratio of 2:1 - A to B.
Acceptable ranges for A are 30-40
Acceptable ranges for B are 15-20

Results for those come back in a test and the values are Compound A at 40 and B at 20. Ratio of 2:1 - Perfect, right?

What if A came back at 80, and B at 40. The ratio is still 2:1, which is what we want, but now we have values that are double what the acceptable ranges are and should investigate.

 

[Hatchet]

Stop all drugs, clean out for a month, get re-tested...