estrogen suppression alone may not be sufficient.
though some important factors that may slow or even abrogate the impacts of estrogen suppression include but not limited to: high body fat, low shbg, high insulin levels (from steroids, exogenous insulin, diet, calorie excess, gh-use), product quality (ie. not 2.5mg/unit or low percentage active- poor synthesis.. or fake), exogenous xenoestrogens, etc...
if you have solely central gland development estrogen is usually the primary factor, when there is puffyness and ductal spread (usually evident from disproportionate lower and outer pec fat- ducts usually spread down and out toward armpit) then prolactin is quite often a signficant factor. in which case pramipexole
at 2.5mg/day most people without high bodyfat, liver issues or aromatase polymorphism will start to see significant joint dryness at 3-4 week range (some will see within days-- )-- the more significant these issues the longer it can take to reach such suppression.